Table_1_Association between specific social activities and depressive symptoms among older adults: A study of urban-rural differences in China.docx

BackgroundEngaging in social activities can help older persons with their depressed symptoms. Few studies, however, have looked into the connection between social interactions and depressed symptoms in Chinese older persons. The aim of this study was to investigate differences in older Chinese individuals' social activity involvement and depressive symptoms across urban and rural settings.MethodsA cross-sectional investigation using information from the 2018 China Health and Retirement Longitudinal Study (CHARLS), which was limited to older individuals aged 60 and over. Generalized linear models were constructed to assess the effects of participants' characteristics and specific social activities on CES-D scores. The association between specific social activities and depressed symptoms was investigated using multivariate logistic regression analysis.ResultsIn this study, it was discovered that older individuals had a prevalence of depressed symptoms of 36.2%, with rural older adults having a greater prevalence of depressive symptoms (39.7%) than urban older adults (30.9%). Our results showed that for urban respondents, providing help to others (not regularly. OR = 0.753, 95% CI: 0.579–0.980, P = 0.035), going to a sport (not regularly. OR = 0.685, 95% CI: 0.508–0.924, P = 0.013), and using the Internet (not regular. OR = 0.613, 95% CI: 0.477–0.789, P ConclusionsAccording to our research, there is a cross-sectional relationship between participating in a specific social activity and depressed symptoms in Chinese older adults, and this relationship varies across urban and rural older adults. This suggests that taking part in specific social activities may be crucial for reducing depression symptoms in older persons, developing more focused interventions that might support healthy aging, and offering a guide for policymakers and activists working to improve the mental health of seniors.</p

Table_2_Association between specific social activities and depressive symptoms among older adults: A study of urban-rural differences in China.docx

BackgroundEngaging in social activities can help older persons with their depressed symptoms. Few studies, however, have looked into the connection between social interactions and depressed symptoms in Chinese older persons. The aim of this study was to investigate differences in older Chinese individuals' social activity involvement and depressive symptoms across urban and rural settings.MethodsA cross-sectional investigation using information from the 2018 China Health and Retirement Longitudinal Study (CHARLS), which was limited to older individuals aged 60 and over. Generalized linear models were constructed to assess the effects of participants' characteristics and specific social activities on CES-D scores. The association between specific social activities and depressed symptoms was investigated using multivariate logistic regression analysis.ResultsIn this study, it was discovered that older individuals had a prevalence of depressed symptoms of 36.2%, with rural older adults having a greater prevalence of depressive symptoms (39.7%) than urban older adults (30.9%). Our results showed that for urban respondents, providing help to others (not regularly. OR = 0.753, 95% CI: 0.579–0.980, P = 0.035), going to a sport (not regularly. OR = 0.685, 95% CI: 0.508–0.924, P = 0.013), and using the Internet (not regular. OR = 0.613, 95% CI: 0.477–0.789, P ConclusionsAccording to our research, there is a cross-sectional relationship between participating in a specific social activity and depressed symptoms in Chinese older adults, and this relationship varies across urban and rural older adults. This suggests that taking part in specific social activities may be crucial for reducing depression symptoms in older persons, developing more focused interventions that might support healthy aging, and offering a guide for policymakers and activists working to improve the mental health of seniors.</p

One-Pot Conversion of <i>N</i>‑Allyl-α-cyano Esters to α‑Allyl-α-cyano Lactams through a Hydrolysis/Ketene Formation/Cyclization/Claisen Rearrangement Sequence

An intramolecular ketene aza-Claisen rearrangement is developed for the first time to enable the stereoselective synthesis of α-ally-α-cyano-lactams from <i>N</i>-allyl amino esters. This reaction also exhibits outstanding chemoselectivity when an unsymmetrical bis-<i>N</i>-allyl group is present in the starting molecule. The usefulness of this method is demonstrated by a short synthesis of optically active bicyclolactam from l-proline

Self-construction of Magnetic Hollow La_0.7Sr_0.3MnO₃ Microspheres with Complex Units

Perovskite structure La_0.7Sr_0.3MnO₃ magnetic hollow microspheres with complex units were prepared via the hydrothermal route without hard and soft templates. The formation of hollow microspheres follows the self-construction mechanism involving oriented attachment, dissolution, and recrystallization processes. It exhibits a ferromagnetic behavior at room temperature

Table_1_Lacticaseibacillus rhamnosus Hao9 exerts antidiabetic effects by regulating gut microbiome, glucagon metabolism, and insulin levels in type 2 diabetic mice.XLSX

IntroductionType 2 diabetes mellitus (T2DM) is a metabolic disease that has led to a significant global public health burden.MethodsIn this work, we investigated the effects of Lacticaseibacillus rhamnosus Hao9 on T2DM in mice with high-fat diet- and streptozotocin (STZ)-induced diabetes (diabetic mice) and explored the underlying mechanisms.ResultsWe found that 109 colony forming units (CFUs) of Hao9 per day significantly reduced fasting blood glucose and insulin levels (p DiscussionThe supplementation of Hao9 improved gut microbiota, glucose metabolism, and insulin levels significantly in T2DM mice. That means Hao9 contributes to improving T2DM symptoms with its potential beneficial effects. Therefore, Hao9 is a promising dietary supplement for the treatment of T2DM.</p

Additional file 8: of Isolated C. elegans germ nuclei exhibit distinct genomic profiles of histone modification and gene expression

Figure S8 Heatmap of H3K4me3 levels for genes with tissue-enriched expression. Heatmap displaying the levels of H3K4me3 for genes with SOM-enriched expression or IGN-enriched expression, as assayed by IGN H3K4me3 ChIP-seq and SOM H3K4me3 ChIP-seq. (PDF 3310 kb

Additional file 1 of Analysis of inappropriate prophylactic use of proton pump inhibitors during the perioperative period: an observational study

Additional file 1. The evaluation criterion

Additional file 9: of Isolated C. elegans germ nuclei exhibit distinct genomic profiles of histone modification and gene expression

Table S1 Quantification of fraction of germline nuclei (DOCX 14 kb

Additional file 14: of Isolated C. elegans germ nuclei exhibit distinct genomic profiles of histone modification and gene expression

IGN_H3K4me3_q0.001_peaks_ce10 (XLSX 3928 kb

Additional file 13: of Isolated C. elegans germ nuclei exhibit distinct genomic profiles of histone modification and gene expression

SOM_H3K27ac_q0.001_peaks_ce10 (XLSX 5600 kb