The envirome and the connectome: exploring the structural noise in the human brain associated with socioeconomic deprivation

Complex cognitive functions are widely recognized to be the result of a number of brain regions working together as large-scale networks. Recently, complex network analysis has been used to characterize various structural properties of the large scale network organization of the brain. For example, the human brain has been found to have a modular architecture i.e. regions within the network form communities (modules) with more connections between regions within the community compared to regions outside it. The aim of this study was to examine the modular and overlapping modular architecture of the brain networks using complex network analysis. We also examined the association between neighborhood level deprivation and brain network structure – modularity and grey nodes. We compared network structure derived from anatomical MRI scans of 42 middle-aged neurologically healthy men from the least (LD) and the most deprived (MD) neighborhoods of Glasgow with their corresponding random networks. Cortical morphological covariance networks were constructed from the cortical thickness derived from the MRI scans of the brain. For a given modularity threshold, networks derived from the MD group showed similar number of modules compared to their corresponding random networks, while networks derived from the LD group had more modules compared to their corresponding random networks. The MD group also had fewer grey nodes – a measure of overlapping modular structure. These results suggest that apparent structural difference in brain networks may be driven by differences in cortical thicknesses between groups. This demonstrates a structural organization that is consistent with a system that is less robust and less efficient in information processing. These findings provide some evidence of the relationship between socioeconomic deprivation and brain network topology

Fuel conservative guidance concept for shipboard landing of powered-life aircraft

A simulation study was undertaken to investigate the application of energy conservative guidance (ECG) software, developed at NASA Ames Research Center, to improve the time and fuel efficiency of powered lift airplanes operating from aircraft carriers at sea. When a flightpath is indicated by a set of initial conditions for the aircraft and a set of positional waypoints with associated airspeeds, the ECG software synthesizes the necessary guidance commands to optimize fuel and time along the specified path. A major feature of the ECG system is the ability to synthesize a trajectory that will allow the aircraft to capture the specified path at any waypoint with the desired heading and airspeed from an arbitrary set of initial conditions. Five paths were identified and studied. These paths demonstrate the ECG system's ability to save flight time and fuel by more efficiently managing the aircraft's capabilities. Results of this simulation study show that when restrictions on the approach flightpath imposed for manual operation are removed completely, fuel consumption during the approach was reduced by as much as 49% (610 lb fuel) and the time required to fly the flightpath was reduced by as much as 41% (5 min). Savings due to ECG were produced by: (1) shortening the total flight time; (2) keeping the airspeed high as long as possible to minimize time spent flying in a regime in which more engine thrust is required for lift to aid the aerodynamic lift; (3) minimizing time spent flying at constant altitude at slow airspeeds; and (4) synthesizing a path from any location for a direct approach to landing without entering a holding pattern or other fixed approach path

ISTRAŽIVANJE MOGUĆNOSTI RASTA KOMARČI DRŽANIH U KOMERCIJALNOM RECIRKULACIJSKOM SISTEMU I TRETIRANIH NUSPROIZVODOM INDUSTRIJSKE PROIZVODNJE GOVEĐEG HORMONA RASTA

Gilthead sea bream, maintained in a commercial scale recirculation system, were subjected to three injections (0,5 and 10 µg -1 body weight) with a by-product from the industrial production of recombinant bovine growth hormone (rbGH). Injections were provided at experiment start and at 3 and 6 weeks. Growth performance of animals was evaluated over a period of 8 weeks (n = 171 per treatment). At trial end fish were examined for proximate composition, fillet yield and visceral indices. No differences were recorded in individual growth performance between the three treatment groups (P > 0.05). Examination of protein productive value and protein efficiency ratio indicated approximately 20% of dietary protein was incorporated into animals irrespective of treatment. However incorporation of dietary lipid decreased with increasing dose of rbGH. High dose GH decreased liver weight (P 0,05). Istraživanje vrijednosti produktivnog proteina i količine efikasnosti proteina pokazalo je da je približno 20% proteina bilo inkorporirano u životinje neovisno o tretmanu. No inkorporacija lipida bila je smanjena povećanjem doze hormona rasta (rbGH). Visoka doza hormona rasta smanjila je težinu jetre (P < 0,05) u usporedbi s kontrolom s istodobnim smanjenjem hepatosomatskog indeksa (P < 0,05). Težina i postotak fileta bili su viši u životinja tretiranih dozom od 10 µg g -1 tjelesne težine u usporedbi s niskom dozom rbGH tretiranih riba (P < 0,05)

Spectropolarimetry of the H-alpha line in Herbig Ae/Be stars

Using the HiVIS spectropolarimeter built for the Haleakala 3.7m AEOS telescope, we have obtained a large number of high precision spectropolarimetrc observations (284) of Herbig AeBe stars collected over 53 nights totaling more than 300 hours of observing. Our sample of five HAeBe stars: AB Aurigae, MWC480, MWC120, MWC158 and HD58647, all show systematic variations in the linear polarization amplitude and direction as a function of time and wavelength near the H-alpha line. In all our stars, the H-alpha line profiles show evidence of an intervening disk or outflowing wind, evidenced by strong emission with an absorptive component. The linear polarization varies by 0.2% to 1.5% with the change typically centered in the absorptive part of the line profile. These observations are inconsistent with a simple disk-scattering model or a depolarization model which produce polarization changes centered on the emmissive core. We speculate that polarized absorption via optical pumping of the intervening gas may be the cause.Comment: Accepted for publication in ApJ Letter

K-Band Spectroscopy of an Obscured Massive Stellar Cluster in the Antennae Galaxies (NGC 4038/4039) with NIRSPEC

We present infrared spectroscopy of the Antennae Galaxies (NGC 4038/4039) with NIRSPEC at the W. M. Keck Observatory. We imaged the star clusters in the vicinity of the southern nucleus (NGC 4039) in 0.39" seeing in K-band using NIRSPEC's slit-viewing camera. The brightest star cluster revealed in the near-IR (M_K(0) = -17.9) is insignificant optically, but coincident with the highest surface brightness peak in the mid-IR (12-18 um) ISO image presented by Mirabel et al (1998). We obtained high signal-to-noise 2.03-2.45 um spectra of the nucleus and the obscured star cluster at R = 1900. The cluster is very young (age ~ 4 Myr), massive (M ~ 16E6 M_sun), and compact (density ~ 115 M_sun pc^(-3) within a 32 pc half-light radius), assuming a Salpeter IMF (0.1-100 M_sun). Its hot stars have a radiation field characterized by T_eff ~ 39,000 K, and they ionize a compact HII region with n_e ~ 10^4 cm^(-3). The stars are deeply embedded in gas and dust (A_V = 9-10 mag), and their strong FUV field powers a clumpy photodissociation region with densities n_H > 10^5 cm^(-3) on scales of ~ 200 pc, radiating L{H_2 1-0 S(1)}= 9600 L_sun.Comment: 4 pages, 4 embedded figures, uses emulateapj.sty. To appear in ApJL. Also available at http://astro.berkeley.edu/~agilber

Smelly maps: the digital life of urban smellscapes

Smell has a huge influence over how we perceive places. Despite its importance, smell has been crucially overlooked by urban planners and scientists alike, not least because it is difficult to record and analyze at scale. One of the authors of this paper has ventured out in the urban world and conducted ``smellwalks'' in a variety of cities: participants were exposed to a range of different smellscapes and asked to record their experiences. As a result, smell-related words have been collected and classified, creating the first dictionary for urban smell. Here we explore the possibility of using social media data to reliably map the smells of entire cities. To this end, for both Barcelona and London, we collect geo-referenced picture tags from Flickr and Instagram, and geo-referenced tweets from Twitter. We match those tags and tweets with the words in the smell dictionary. We find that smell-related words are best classified in ten categories. We also find that specific categories (e.g., industry, transport, cleaning) correlate with governmental air quality indicators, adding validity to our study

The First Ultra-cool Brown Dwarf Discovered by the Wide-field Infrared Survey Explorer

We report the discovery of the first new ultra-cool brown dwarf (BDs) found with the Wide-field Infrared Survey Explorer (WISE). The object’s preliminary designation is WISEPC J045853.90+643451.9. Follow-up spectroscopy with the LUCIFER instrument on the Large Binocular Telescope indicates that it is a very late-type T dwarf with a spectral type approximately equal to T9. Fits to an IRTF/SpeX 0.8–2.5 μm spectrum to the model atmospheres of Marley and Saumon indicate an effective temperature of approximately 600 K as well as the presence of vertical mixing in its atmosphere. The new BD is easily detected by WISE, with a signal-to-noise ratio of ~36 at 4.6 μm. Current estimates place it at a distance of 6–10 pc. This object represents the first in what will likely be hundreds of nearby BDs found by WISE that will be suitable for follow-up observations, including those with the James Webb Space Telescope. One of the two primary scientific goals of the WISE mission is to find the coolest, closest stars to our Sun; the discovery of this new BD proves that WISE is capable of fulfilling this objective

Strong Nebular Line Ratios in the Spectra of z~2-3 Star-forming Galaxies: First Results from KBSS-MOSFIRE

We present initial results of a deep near-IR spectroscopic survey covering the 15 fields of the Keck Baryonic Structure Survey (KBSS) using MOSFIRE on the Keck 1 telescope, focusing on a sample of 251 galaxies with redshifts 2.0< z < 2.6, star-formation rates 2 < SFR < 200 M_sun/yr, and stellar masses 8.6 < log(M*/M_sun) < 11.4, with high-quality spectra in both H- and K-band atmospheric windows. We show unambiguously that the locus of z~2.3 galaxies in the "BPT" nebular diagnostic diagram exhibits a disjoint, yet similarly tight, relationship between the ratios [NII]6585/Halpha and [OIII]/Hbeta as compared to local galaxies. Using photoionization models, we argue that the offset of the z~2.3 locus relative to z~ 0 is explained by a combination of harder ionizing radiation field, higher ionization parameter, and higher N/O at a given O/H than applies to most local galaxies, and that the position of a galaxy along the z~2.3 star-forming BPT locus is surprisingly insensitive to gas-phase oxygen abundance. The observed nebular emission line ratios are most easily reproduced by models in which the net ionizing radiation field resembles a blackbody with effective temperature T_eff = 50000-60000 K and N/O close to the solar value at all O/H. We critically assess the applicability of commonly-used strong line indices for estimating gas-phase metallicities, and consider the implications of the small intrinsic scatter in the empirical relationship between excitation-sensitive line indices and stellar mass (i.e., the "mass-metallicity" relation), at z~2.3.Comment: 41 pages, 25 figures, accepted for publication in the Astrophysical Journal. Version with full-resolution figures available at http://www.astro.caltech.edu/~ccs/mos_bpt_submit.pd