40 research outputs found
Tap 'N' Shake: Gesture-based Smartwatch-Smartphone Communications System
Smartwatches have recently seen a surge in popularity, and the new technology presents a number of interesting opportunities and challenges, many of which have not been adequately dealt with by existing applications. Current smartwatch messaging systems fail to adequately address the problem of smartwatches requiring two-handed interactions. This paper presents Tap 'n' Shake, a novel gesture-based messaging system for Android smartwatches and smartphones addressing the problem of two-handed interactions by utilising various motion-gestures within the applications. The results of a user evaluation carried out with sixteen subjects demonstrated the usefulness and usability of using gestures over two-handed interactions for smartwatches. Additionally, the study provides insight into the types of gestures that subjects preferred to use for various actions in a smartwatch-smartphone messaging system
Tap'n'shake:gesture-based smartwatch-smartphone communications system
Smartwatches have recently seen a surge in popularity, and the new technology presents a number of interesting opportunities and challenges, many of which have not been adequately dealt with by existing applications. Current smartwatch messaging systems fail to adequately address the problem of smartwatches requiring two-handed interactions. This paper presents Tap 'n' Shake, a novel gesture-based messaging system for Android smartwatches and smartphones addressing the problem of two-handed interactions by utilising various motion-gestures within the applications. The results of a user evaluation carried out with sixteen subjects demonstrated the usefulness and usability of using gestures over two-handed interactions for smartwatches. Additionally, the study provides insight into the types of gestures that subjects preferred to use for various actions in a smartwatch-smartphone messaging system
Apollo Meets Dionysus: Interdisciplinarity in Long-standing Interdisciplinary Programs
At the invitation of the Association for Integrative Studies (AIS) Board of Directors, representatives of several long- standing interdisciplinary programs gathered on October 9, 2003, to participate in back-to-back panel discussions at the 25th AIS conference. Following months of email exchanges prior to the conference, the panel moved quickly into an exploration of the common issues faced by such programs. Many, the panel discovered, can be examined fruitfully by extending Nietzsche’s distinction between the Apollonian and Dionysian, applied by him to tragedy, to an overview of experimental, interdisciplinary programs. In the panel discussion, it became apparent that this distinction could serve as a useful metaphorical lens through which to view many of the tensions that shaped the structures and practices of the programs represented. Since those structures and practices, in turn, influenced how faculty members and students each came to understand the interdisciplinary approach to education common to these programs, the panelists came to appreciate that the insights gained from viewing interdisciplinary education as an outcome of Apollonian-Dionysian tension are of more than passing or parochial interest
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Infection's Sweet Tooth: How Glycans Mediate Infection and Disease Susceptibility
Glycans form a highly variable constituent of our mucosal surfaces and profoundly affect our susceptibility to infection and disease. The diversity and importance of these surface glycans can be seen in individuals who lack a functional copy of the fucosyltransferase gene, FUT2. Representing around one-fifth of the population, these individuals have an altered susceptibility to many bacterial and viral infections and diseases. The mediation of host-pathogen interactions by mucosal glycans, such as those added by FUT2, is poorly understood. We highlight, with specific examples, important mechanisms by which host glycans influence infection dynamics, including by: acting as pathogen receptors (or receptor-decoys), promoting microbial stability, altering the physical characteristics of mucus, and acting as immunological markers. We argue that the effect glycans have on infection dynamics has profound implications for many aspects of healthcare and policy, including clinical management, outbreak control, and vaccination policy
Impact of Probiotic B. infantis EVC001 Feeding in Premature Infants on the Gut Microbiome, Nosocomially Acquired Antibiotic Resistance, and Enteric Inflammation
Background: Preterm birth is a major determinant of neonatal survival and morbidity, but the gut microbiome and associated enteric inflammation are also key factors in neonatal development and the risk of associated morbidities. We prospectively and longitudinally followed two cohorts of preterm infants, one of which was fed activated Bifidobacterium longum subsp. infantis (B. infantis) EVC001 8 × 109 CFU daily, and the other was not fed a probiotic. Hospital feeding protocol assigned all infants born at \u3c 1500 g and/or \u3c 32 weeks corrected gestational age to the probiotic feeding protocol, whereas infants born at \u3e 1500 g and/or \u3e 32 weeks corrected gestational age were not fed a probiotic. Fecal samples were opportunistically collected from 77 infants throughout the hospital stay, and subjected to shotgun metagenomic sequencing and quantification of enteric inflammation. De-identified metadata was collected from patient medical records.
Results: The gut microbiome of preterm infants was typified by a high abundance of Enterobacteriaceae and/or Staphylococcaceae, and multivariate modeling identified the probiotic intervention, rather than degree of prematurity, day of life, or other clinical interventions, as the primary source of change in the gut microbiome. Among infants fed B. infantis EVC001, a high abundance of total Bifidobacteriaceae developed rapidly, the majority of which was B. infantis confirmed via subspecies-specific qPCR. Associated with this higher abundance of Bifidobacteriaceae, we found increased functional capacity for utilization of human milk oligosaccharides (HMOs), as well as reduced abundance of antibiotic resistance genes (ARGs) and the taxa that harbored them. Importantly, we found that infants fed B. infantis EVC001 exhibited diminished enteric inflammation, even when other clinical variables were accounted for using multivariate modeling.
Conclusion: These results provide an important observational background for probiotic use in a NICU setting, and describe the clinical, physiological, and microbiome- associated improvements in preterm infants associated with B. infantis EVC001 feeding
Estimating the Costs and Benefits of Providing Free Public Transit Passes to Students in Los Angeles County: Lessons Learned in Applying a Health Lens to Decision-Making
In spite of increased focus by public health to engage and work with non-health sector partners to improve the health of the general as well as special populations, only a paucity of studies have described and disseminated emerging lessons and promising practices that can be used to undertake this work. This article describes the process used to conduct a Health Impact Assessment of a proposal to provide free public transportation passes to students in Los Angeles County. This illustrative case example describes opportunities and challenges encountered in working with an array of cross-sector partners and highlights four important lessons learned: (1) the benefits and challenges associated with broad conceptualization of public issues; (2) the need for more comprehensive, longitudinal data systems and dynamic simulation models to inform decision-making; (3) the importance of having a comprehensive policy assessment strategy that considers health impacts as well as costs and feasibility; and (4) the need for additional efforts to delineate the interconnectivity between health and other agency priorities. As public health advances cross-sector work in the community, further development of these priorities will help advance meaningful collaboration among all partners
Survey of Patients' Knowledge and Opinions regarding the Use of Indwelling Urinary Catheters
FUT2 genotype influences lung function, exacerbation frequency and airway microbiota in non-CF bronchiectasis
Objective To assess whether FUT2 (secretor) genotype affects disease severity and airway infection in patients with non-cystic fibrosis bronchiectasis. Participants Induced sputum samples were obtained from 112 adult patients with high-resolution CT scan-proven bronchiectasis and at least two exacerbations in the previous year, as part of an unrelated randomised control trial. Outcome measures Presence of null FUT2 polymorphisms were determined by gene sequencing and verified by endobronchial biopsy histochemical staining. Outcome measures were FEV 1 % predicted, exacerbation frequency, and bacterial, fungal and viral components of the microbiota (measured by culture independent approaches). Results Patients were grouped by FUT2 loss-of-function genotype; categorised as non-secretors (n=27, sese), heterozygous secretors (n=54, Sese) or homozygous secretors (n=31, SeSe). FEV 1 % was significantly lower in SeSe patients compared with sese patients (mean 61.6 (SD 20.0) vs 74.5 (18.0); p=0.023). Exacerbation frequency was significantly higher in SeSe (mean count 5.77) compared with sese (4.07; p=0.004) and Sese (4.63; p=0.026) genotypes. The time until first exacerbation was significantly shorter in SeSe compared with Sese (HR=0.571 (95% CI 0.343 to 0.950); p=0.031), with a similar trend for sese patients (HR=0.577 (0.311 to 1.07); p=0.081). sese had a significantly reduced frequency of Pseudomonas aeruginosa-dominated airway infection (8.7%) compared with Sese (31%; p=0.042) and SeSe (36%; p=0.035). In contrast, fungal, viral and non-dominant bacterial components of the microbiome were not significantly different between FUT2 genotypes. Conclusions FUT2 genotype in patients with non-cystic fibrosis bronchiectasis was significantly associated with disease outcomes, with homozygous secretors exhibiting lower lung function, higher exacerbation number and a higher frequency of P. aeruginosa-dominated infection. Trial registration number ACTRN12609000578202 (anzctr.org.au); Pre-results
The Effect Of Technology Use On Productivity Growth
This paper examines the relationship between the use of advanced technologies and productivity and productivity growth rates. We use data from the 1993 and 1988 Survey of Manufacturing Technology (SMT) to examine the use of advanced (computer based) technologies at two different points in time. We also are able to combine the survey data with the Longitudinal Research Database (LRD) to examine the relationships between plant performance, plant characteristics, and the use of advanced technologies. In addition, a subset of these plants were surveyed in both years, enabling us to directly associate changes in technology use with changes in plant productivity performance. The main findings of the study are as follows. First, diffusion is not the same across the surveyed technologies. Second, the adoption process is not smooth: plants added and dropped technologies over the six-year interval 1988-93. In fact, the average plant showed a gross change of roughly four technologies in achieving an average net increase of less than one new technology. In this regard, technology appears to be an experience good: plants experiment with particular technologies before deciding to add additional units or drop the technology entirely. We find that establishments that use advanced technologies exhibit higher productivity. This relationship is observed in both 1988 and 1993 even after accounting for other important factors associated with productivity: size, age, capital intensity, labor skill mix, and other controls for plant characteristics such as industry and region. In addition, the relationship between productivity and advanced technology use is observed both in the extent of technologies used and the intensity of their use. Finally, while there is some evidence that the use of advanced technologies is positively related to improved productivity performance, the data suggest that the dominant explanation for the observed cross-section relationship is that good performers are more likely to use advanced technologies than poorly performing operations.technology, productivity, JEL Classification: L1, L6, D92,