62 research outputs found

    Sod webworm (Lepidoptera: Pyralidae: Crambinae) moths collected in light traps

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    Thirteen species of sod webworm moths were collected during 1968. Distinct differences in fijght dates occurred among the species. Trap data indicated that seven species were univoltine while six were most likely multivoltine. Sod webworm species collected as adults in light traps from May to October: Pediasia trisecta, P mutabilis, Chrysoteuchia topiaria, Agriphila vulgivagella, A. ruricolella, Microcrambus elegans, Argyria nivalis, Crambus alboclavellus, C. praefectellus, C. laquetellus, C. leachellus, C. satrapellu

    Hatching of Sod Webworm Eggs in Relation to Low and High Temperatures

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    Eggs of 12 species of sod webworm were exposed for various periods to temperatures of 0, 10, and 45°C. Hatchability was compared with control eggs kept at 25°C. Short exposures to any temperature did not significantly affect percent hatch. Prolonged exposure resulted in a significant decrease in hatchability for several species at 0° and for all species at 45°C. There was a significant difference in hatchability between the 3 generations of Crambus teterrellus (Zincken) and of Pediasia trisecta (Walker) at extreme temperatures. Populations of Agriphila ruricolella (Zeller), collected at 2 elevations, differed significantly in hatching percentage and developmental rate

    Hatching of Sod Webworm Eggs in Relation to Low Temperatures

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    Eggs of Chrysoteuchia topiaria (Zeller), Crambus pascuellus floridus (Zeller), and Pediasia trisecta (Walker) were exposed to temperatures of 25, 15, 10, 4, and –10°C. Only those of P. trisecta hatched after exposure to 4°C for 30 days, while none hatched after exposure to –10°C. Eggs of none of the species hatched after exposure to 4 and 10°C for 60 days. Pre-exposure and post-exposure conditioning had no significant effect on percent hatch of P. trisecta eggs, while length of exposure period had a significant effect

    Seasonal Abundance and Distribution of Benthic Fauna within a Pond

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    A Tennessee pond was sampled weekly from June 18 to August 20, 1968, to determine quantitative differences among benthic organisms in sampling depths and dates. Annelids (Oligochaeta), Chironomidae larvae, and Chaoboridae larvae were the dominant organisms collected. Preferred depths existed for each group of organisms. Chaoboridae and Chironomidae exhibited distinct seasonal variations in numbers, with the population decreasing throughout the summer. Chaoboridae were the most and Chironomidae the least numerous of the 3 groups

    Chorion Characteristics of Sod Webworm Eggs

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    The egg chorion was investigated for 15 species of sod webworm moths (Lepidoptera: Pyralidae: Crambinae) collected in Tennessee. Liquid plastic was used for surface printing of chorion sculpturing. Scanning electron micrographs were utilized in construction of a taxonomic key to eggs of the Crambinae species studied and the characteristics illustrated

    Control of Leaf-Feeding Insects on Yellow-Poplar

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    Yellow-poplar, Liriodendron tulipifera L., also known as the tulip-poplar, is an important source of pulpwood and saw timber, and it is widely used as a shade tree. Numerous insect species attack the foliage of yellow-poplar. In 1965, Odontopus calceatus (Say) was first observed seriously damaging yellow-poplar in Tennessee (Russell and Stanley 1967). Defoliation was so severe at the University of Tennessee Oak Ridge Forest Experiment Station that growth reduction was attributed to this pest (Buckner 1972). In 1967, observations by one of us (E.A.H.) indicated that several other insects attack yellow-poplar leaves during the spring. Infestations of the aphid Macrosiphum liriodendri (Monell) and gall midges, Cecidomyia sp. and Thecodiplosis liriodendri Osten Sachen, were common. Cecidomyia sp. was called tulip vein gall, and T. liriodendri tulip spot gall, by Felt (1940), who described their damage. Since no measures had been determined for their control, a series of tests was conducted to determine the efficacy of various insecticide treatments

    The response of Kentucky bluegrass turf to insecticidal treatments

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    The most common insect pests of Kentucky bluegrass (Poa pratensis L.) in Tennessee are sod webworms and white grubs. Attempts to control these insects with insecticides has, at times, resulted in the entire destruction of the lawn by sod webworms. Pass (1965) has shown that applications of aldrin, chlordane, and dieldrin increased the webworm population 2-3 fold. Streu and Vasvary (1966) found the same phenomenon in chinch bug control. Both Pass and Streu believed that this population increase of the target pest may have been related to an interference in some population-limiting mechanism, such as the natural enemies, but neither investigator definitely proved this. In view of the problem that home owners have had after applying insecticides for webworm and grub control, it was decided to conduct a study to determine the overall effects of insecticides on bluegrass. The research reported herein covers only a preliminary phase of that study: the effect of insecticides on botanical composition of a bluegrass turf

    Concert recording 2018-03-09a

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    [Track 1]. Sonata in E major, BWV 1035. I. Adagio ma non tanto [Track 2]. II. Allegro [Track 3]. III. Siciliano / J.S. Bach -- [Track 4]. Madrigal / Philippe Gaubert -- [Track 5]. Sonata no. 3 in G major. I. Adagio II. Allegro / G.F. Handel -- [Track 6]. Sonata for flute and piano. I. Allegro scherzando / Otar Taktakishvili -- [Track 7]. Sonata in A minor, WQ 132 for solo flute. I. Poco adagio / C.P.E. Bach -- [Track 8]. Duo no. 1, op. 80. I. Allegro con gusto / Friedrich Kahlau -- [Track 9]. Suite modale. I. Adagio / Ernest Bloch -- [Track 10]. Maya / Ian Clarke -- [Track 11]. Ballade, op. 288 / Carl Reinecke -- [Track 12]. Fantasie, op. 79 / Gabriel Fauré -- [Track 13]. Duettino for two flutes and piano, op. 36 / Francis Doppler

    A Phase I, First-in-Human Study of GSK2849330, an Anti-HER3 Monoclonal Antibody, in HER3-Expressing Solid Tumors

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    Background GSK2849330, an anti-HER3 monoclonal antibody that blocks HER3/Neuregulin 1 (NRG1) signaling in cancer cells, is engineered for enhanced antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. This phase I, first-in-human, open-label study assessed the safety, pharmacokinetics (PK), pharmacodynamics, and preliminary activity of GSK2849330 in patients with HER3-expressing advanced solid tumors. Patients and Methods Patients with various tumor types were prospectively selected for HER3 expression by immunohistochemistry; a subset was also screened for NRG1 mRNA expression. In the dose-escalation phase, patients received GSK2849330 1.4-30 mg/kg every 2 weeks, or 3 mg/kg or 30 mg/kg weekly, intravenously (IV). In the dose-expansion phase, patients received 30 mg/kg GSK2849330 IV weekly. Results Twenty-nine patients with HER3-expressing cancers, of whom two expressed NRG1, received GSK2849330 (dose escalation: n = 18, dose expansion: n = 11). GSK2849330 was well tolerated. No dose-limiting toxicities were observed. The highest dose, of 30 mg/kg weekly, expected to provide full target engagement, was selected for dose expansion. Treatment-emergent adverse events (AEs) were mostly grade 1 or 2. The most common AEs were diarrhea (66%), fatigue (62%), and decreased appetite (31%). Dose-proportional plasma exposures were achieved, with evidence of HER3 inhibition in paired tissue biopsies. Of 29 patients, only 1 confirmed partial response, lasting 19 months, was noted in a patient with CD74-NRG1-rearranged non-small cell lung cancer (NSCLC). Conclusion GSK2849330 demonstrated a favorable safety profile, dose-proportional PK, and evidence of target engagement, but limited antitumor activity in HER3-expressing cancers. The exceptional response seen in a patient with CD74-NRG1-rearranged NSCLC suggests further exploration in NRG1-fusion-positive cancers. Implications for Practice This first-in-human study confirms that GSK2849330 is well tolerated. Importantly, across a variety of HER3-expressing advanced tumors, prospective selection by HER3/NRG1 expression alone was insufficient to identify patients who could benefit from treatment with this antibody-dependent cell-mediated cytotoxicity- and complement-dependent cytotoxicity-enhanced anti-HER3 antibody. The only confirmed durable response achieved was in a patient with CD74-NRG1-rearranged lung cancer. This highlights the potential utility of screening for NRG1 fusions prospectively across tumor types to enrich potential responders to anti-HER3 agents in ongoing trials

    Concert recording 2018-02-09

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    [Track 1]. Marche á huit instrumens á vent / Nannette Streicher -- [Track 2]. Dixtuor pour instruments á vent. I. Allegro moderato II. Moderato [Track 3]. III. Andante - Allegro scherzando [Track 4]. IV. Cantabile [Track 5]. V. Allegro risoluto / Claude Arrieu, née Louise Marie Simon -- [Track 6]. Octet for windinstruments / Tera de Marez Oyens -- [Track 7]. The unfortunate traveller, suite for brass band. I. Introduction II. Scherzo [Track 8]. III. Interlude [Track 9]. IV. March / Imogen Holst
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