dataset_Wagner_Hepcidin-25_in_diabetic_CKD

dataset_Wagner_Hepcidin-25_in_diabetic_CK

Panel cointegrating polynomial regressions: group-mean fully modified OLS estimation and inference

We develop group-mean fully modified OLS (FM-OLS) estimation and inference for panels of cointegrating polynomial regressions, i.e., regressions that include an integrated process and its powers as explanatory variables. The stationary errors are allowed to be serially correlated, the integrated regressors – allowed to contain drifts – to be endogenous and, as usual in the panel literature, we include individual-specific fixed effects and also allow for individual-specific time trends. We consider a fixed cross-section dimension and asymptotics in the time dimension only. Within this setting, we develop cross-section dependence robust inference for the group-mean estimator. In both the simulations and an illustrative application estimating environmental Kuznets curves (EKCs) for carbon dioxide emissions we compare our group-mean FM-OLS approach with a recently proposed pooled FM-OLS approach of de Jong and Wagner.</p

Spectroscopic and Computational Studies of the Intramolecular Hydrogen Bonding of 2-Indanol

2-Indanol in its most stable form is stabilized by internal hydrogen bonding, which exists between the hydroxyl hydrogen atom and the π-cloud of the benzene ring. A comprehensive ab initio calculation using the MP2/cc-pVTZ level of theory showed that 2-indanol can exist in four possible conformations, which can interchange through the ring-puckering vibration and the internal rotation of the OH group on the five-membered ring. A potential energy surface in terms of these two vibrational coordinates was calculated. Density functional theory calculations were used to predict the vibrational frequencies and to help in normal mode assignments. Fluorescence excitation spectra of 2-indanol confirm the presence of the four conformers in the electronic ground and excited states. The spectral intensities indicate that, at 90 °C, 82% of the molecules exist in its most stable form with the intramolecular hydrogen bonding. The other isomers are present at approximately 11, 5, and 3%. The MP2/6-311++G(d,p) calculation predicts a distribution of 70, 13, 9, and 8% at 90°C, the experimental sample temperature

Table_1_The Saprophytic Lifestyle of Listeria monocytogenes and Entry Into the Food-Processing Environment.xlsx

Listeria monocytogenes is an environmentally adapted saprophyte that can change into a human and animal bacterial pathogen with zoonotic potential through several regulatory systems. In this review, the focus is on the occurrence of Listeria sensu stricto and sensu lato in different ecological niches, the detection methods, and their analytical limitations. It also highlights the occurrence of L. monocytogenes genotypes in the environment (soil, water, and wildlife), reflects on the molecular determinants of L. monocytogenes for the saprophytic lifestyle and the potential for antibiotic resistance. In particular, the strain-specific properties with which some genotypes circulate in wastewater, surface water, soil, wildlife, and agricultural environments are of particular interest for the continuously updating risk analysis.</p

The EU and protracted displacement: providing solutions or creating obstacles?

In this paper, we explore how the European Union (EU) legal and policy framework relates to protracted displacement. To this end, we examine the existing legal, policy and institutional framework both in the EU and globally, including the Common European Asylum System (CEAS), the 2015 ‘European Agenda on Migration’, and the New Pact on Migration and Asylum. Analytically, we employ Norbert Elias’ concept of ‘figurations’ as a conceptual lens to describe and identify distinct constellations of relationships, norms and social interactions between different actors shaping approaches towards protracted displacement. We argue that policies on protracted displacement are shaped by a triangle of three figurations – the migration security figuration, the humanitarian refugee relief figuration, and the protection-rights figuration. We trace how the migration-security figuration has gained the upper hand in recent years and what this means for EU policies addressing protracted displacement. We conclude that the EU is an actor that facilitates, rather than addresses, protracted displacement, and the Pact on Migration and Asylum further cements that role

Systematic Review of Toxicity Removal by Advanced Wastewater Treatment Technologies via Ozonation and Activated Carbon

Upgrading wastewater treatment plants (WWTPs) with advanced technologies is one key strategy to reduce micropollutant emissions. Given the complex chemical composition of wastewater, toxicity removal is an integral parameter to assess the performance of WWTPs. Thus, the goal of this systematic review is to evaluate how effectively ozonation and activated carbon remove in vitro and in vivo toxicity. Out of 2464 publications, we extracted 46 relevant studies conducted at 22 pilot or full-scale WWTPs. We performed a quantitative and qualitative evaluation of in vitro (100 assays) and in vivo data (20 species), respectively. Data is more abundant on ozonation (573 data points) than on an activated carbon treatment (162 data points), and certain in vitro end points (especially estrogenicity) and in vivo models (e.g., daphnids) dominate. The literature shows that while a conventional treatment effectively reduces toxicity, residual effects in the effluents may represent a risk to the receiving ecosystem on the basis of effect-based trigger values. In general, an upgrade to ozonation or activated carbon treatment will significantly increase toxicity removal with similar performance. Nevertheless, ozonation generates toxic transformation products that can be removed by a post-treatment. By assessing the growing body of effect-based studies, we identify sensitive and underrepresented end points and species and provide guidance for future research

Laboratory Findings.

<p>Laboratory Findings, MELD- /Child Pugh-Score/ demand for blood tranfusion of study patients with SEMS (Self Expandible Metal Stent) treatment. D0 = Day of hospital admission. D3 = Day 3 after hospital admission. Chemical units in brackets.</p><p>Laboratory Findings.</p

Enrollment and outcomes of study patients.

<p>Enrollment and outcomes of study patients.</p

Patients with conventional treatment for variceal bleeding (n = 71).

<p>Description of patients with variceal bleeding and conventional treatment: tabular description of patients average age, sex, prevalence of cirrhosis, etiology of cirrhosis, prevalence of previous bleeding episodes, distribution of varices, Paquet Grade and Child-Pugh Score Classes.</p><p>Patients with conventional treatment for variceal bleeding (n = 71).</p