ProtoDUNEs

These proceedings review the two DUNE prototype detectors, namely Single- and Dual-Phase ProtoDUNEs. The detectors, both employing liquid argon Time Projection Chambers (LAr TPCs), are currently being built at CERN as part of the ProtoDUNE experimental programme. Such R&D programme aims at validating the prototypes design and technology, which will eventually be applied to the DUNE Far Detector at the Sanford Underground Research Facility (SURF).Comment: Talk presented at NuPhys2016 (London, 12-14 December 2016). 8 pages, LaTeX, 3 figure

Safety Evaluation of New Polymer Materials Proposed for Relining Drinking Water Pipes in the City of Milano

Relining is a trenchless technology of recoating the inside walls of damaged water pipes using composite materials. In the Safe Pipe project, co-financed by Regione Lombardia, alternative polymeric materials for relining the drinking water distribution system of the city of Milan have been developed. Relining polymers have been evaluated for their toxicity. The identification of product impurities was performed by HPLC/HRMS and GC/MS analysis and safety evaluation was conducted applying toxicity data, when available, or applying QSAR models. Results showed low level of toxic substances in polymerized resins and in water samples in a migration/leaching test performed in a field experiment

ChatGPT, be my teaching assistant! Automatic correction of SQL exercises

The use of Large Language Models (LLMs) such as OpenAI ChatGPT to enhance teachers’ and learners’ experience has become established. The impressive capabilities of ChatGPT in solving Text2SQL problems prompts their use in database courses to solve SQL exercises. In this paper, we dig deep into ChatGPT abilities applied to SQL exercises. We quantitatively and qualitatively evaluate the performance of a ChatGPT-as-a- SQL-assistant on benchmark data, with particular attention paid to its ability to correctly detect syntactic and semantic errors, provide insightful judgment explanations, and assign grades comparable to those of human teachers. Furthermore, we also analyze the benefits of leveraging few-shot learning to adapt LLM responses to the expectation

Perfusion-CT monitoring of cryo-ablated renal cells tumors

<p>Abstract</p> <p>Background</p> <p>No single and thoroughly validated imaging method in monitoring of cryoablated renal cell carcinoma (RCC) is available. The purpose of our study was to determine the feasibility of dynamic contrast-enhanced perfusion CT (pCT) in evaluating the hemodynamic response of RCC.</p> <p>Methods</p> <p>15 patients (14 male, 1 female; age range, 43-81 years; mean age, 62 years) with cryoablated RCC via a transperitoneal approach, underwent to pCT 6-8 months after cryo-therapy. pCT was performed for 65 seconds after intravenous injection of contrast medium (80 mL, 370 mg iodine per millilitre, 4 mL/sec). Perfusion parameters (Time/Density curve; Blood flow, BF; Blood Volume, BV; Mean Transit Time, MTT; Permeability-Surface Area Product, PS) were sampled in the cryoablated tumor area and in ipsilateral renal cortex using deconvolution-based method. A tumor was considered to be not responsive to treatment by CT evidence of pathological contrast enhancement in the cryoablated area or renal mass persistence compared with the preoperative CT control. Written informed consent was obtained from all participants before the study.</p> <p>Results</p> <p>After cryotherapy, successfully ablated tumor (n = 13) showed decrease in BV (5,39 +/- 1,28 mL/100 g), BF (69,92 +/- 20,12 mL/100 g/min) and PS (16,66 +/- 5,67 mL/100 g/min) value and increased value of MTT (25,35 +/- 4,3 sec) compared with those of normal renal cortex (BV: 117,86 +/- 31,87 mL/100 g/min; BF: 392,39 +/- 117,32 mL/100 g/min; MTT: 18,02 +/- 3,6 sec; PS: 81,68 +/- 22,75 mL/100 g/min). In one patient, assessment of perfusion parameters was not feasible for breathing artifacts. One tumor showed poor response to treatment by the evidence of nodular contrast enhancement in the region encompassing the original lesion. Two typical enhancement patterns were obtained comparing the Time-Density curves of responsive and not responsive ablated tumors.</p> <p>Conclusion</p> <p>Perfusion CT seems to be a feasible and promising technique in monitoring the effects of cryoablation therapy.</p

Effects of whey protein supplement in the elderly submitted to resistance training:systematic review and meta-analysis

Aim: We performed a systematic review to map the evidence and analyze the effect of whey protein supplementation in the elderly submitted to resistance training.  Methods: A comprehensive search on Medline, LILACS, EMBASE, and the Cochrane Library for relevant publications was conducted until August 2015. The terms used in the search were: “Resistance training”; “Whey protein”; “Elderly”.  Results: A total of 632 studies were screened. Five studies were included composing a sample of 391 patients. The supplement whey protein was associated with higher total protein ingestion 9.40 (95% CI: 4.03–14.78), and with an average change in plasma leucine concentration. The supplementation was also associated with increased mixed muscle protein synthesis 1.26 (95% CI: 0.46–2.07) compared to the control group.  Conclusion: We observed an increase in total protein intake, resulting in increased concentration of leucine and mixed muscle protein fractional synthesis rate

Search for dark photons using a multilayer dielectric haloscope equipped with a single-photon avalanche diode

We report on the results of the search for dark photons with mass around 1.5$\,\rm eV/c^2$ using a multilayer dielectric haloscope equipped with an affordable and commercially available photosensor. The multilayer stack, which enables the conversion of dark photons (DP) to Standard Model photons, is made of 23 bilayers of alternating SiO$_2$ and Si$_3$N$_4$ thin films with linearly increasing thicknesses through the stack (a configuration known as a "chirped stack"). The thicknesses have been chosen according to an optimisation algorithm in order to maximise the DP-photon conversion in the energy region where the photosensor sensitivity peaks. This prototype experiment, baptised MuDHI (Multilayer Dielectric Haloscope Investigation) by the authors of this paper, has been designed, developed and run at the Astroparticle Laboratory of New York University Abu Dhabi, which marks the first time a dark matter experiment has been operated in the Middle East. No significant signal excess is observed, and the method of maximum log-likelihood is used to set exclusion limits at $90\%$ confidence level on the kinetic mixing coupling constant between dark photons and ordinary photons

Effects of Energy Drink Acute Assumption in Gastrointestinal Tract of Rats

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Study of dark counts in optical superconducting transition-edge sensors

Superconducting transition-edge sensors (TESs), known for their high single-photon detection efficiency and low background, are increasingly being used in rare event searches. We present the first comprehensive characterization of optical TES backgrounds, identifying three event types: high-energy, electrical noise, and photon-like events. We experimentally verify and simulate the source of the high-energy events. We develop an algorithm to isolate photon-like events, the expected signal in dark matter searches, achieving record-low photon-like dark count rates in the 0.8-3.2 eV energy range