Relationship between El Nino and summer monsoon rainfall over Pakistan

The present paper deals with the influence of El Nino event on the summer monsoon rainfall over Pakistan. The correlation between monthly rainfall of summer monsoon season and bi-Monthly Multivariate ENSO Index (MEI) has been calculated to see the influence of El Nino on the summer monsoon rainfall. MEI is bimonthly ENSO Index pertaining to the period from first week of previous month to first week of the month under consideration. While study the correlation's with the ENSO events out side the Pacific Ocean MEI is more appropriate than other indices like Southern Oscillation Index (SOI) as MEI integrates complete information on ENSO viz. six oceanic and meteorological variables over the tropical Pacific. The results of the study show that there is a tendency of reduction in summer monsoon rainfall over Pakistan during El Nino years. The deficiency in % rainfall is statistically significant up to 90% level during July and September months. It is interesting to note that Pakistan receives more than normal rainfall during summer monsoon season in the immediate following year after the El Nino event. The correlation analysis is also performed on the summer monsoon months for individual provinces of Pakistan. All provinces receive deficient rainfall during monsoon months. The deficiency in rainfall over Punjab during all monsoon months is significant, whereas the deficiency in rainfall is significant during July and August over NWFP and Sindh respectively. No significant impact of El Nino on the summer monsoon rainfall over Baluchistan is observed

Fulminant invasive aspergillosis of the mediastinum in an immunocompetent host: a case report

Introduction: Invasive aspergillosis is a serious complication in immunocompromised patients. It is an opportunistic disease, which predominantly occurs in the lungs, although dissemination to virtually any organ is possible. Invasive aspergillosis in an immunocompetent patient with extension to the mediastinum has rarely been reported. Here, we present the case of a patient with no apparent immunodeficiency state, who presented with Aspergillus endocarditis and fulminant invasive aspergillosis with extensive involvement of the mediastinal structures, which ultimately was responsible for her death. To the best of our knowledge, this is the first reported case in the literature on fulminant invasive mediastinal aspergillosis with extension to the pulmonary vasculature and concomitant Aspergillus endocarditis in an apparently immunocompetent patient without pre-existing lung disease. Case presentation: Our patient was a previously healthy 47-year-old Asian woman, who presented to our emergency room with severe progressive shortness of breath of one month’s duration, associated with orthopnea and unstable vital signs. Conclusion: Invasive aspergillosis has been described in the presence of pulmonary disease, such as chronic obstructive pulmonary disorder, and one case has been reported in a patient without preexistent disease, but none of these have been fatal. Our case is therefore the first reported case of its kind. Our case shows that fulminant aspergillosis can occur in an immunocompetent host and can be fatal. We conclude that invasive aspergillosis should not be excluded from the differential diagnosis on the basis of immunocompetency