Modeling of thermally induced skew variations in clock distribution network

Clock distribution network is sensitive to large thermal gradients on the die as the performance of both clock buffers and interconnects are affected by temperature. A robust clock network design relies on the accurate analysis of clock skew subject to temperature variations. In this work, we address the problem of thermally induced clock skew modeling in nanometer CMOS technologies. The complex thermal behavior of both buffers and interconnects are taken into account. In addition, our characterization of the temperature effect on buffers and interconnects provides valuable insight to designers about the potential impact of thermal variations on clock networks. The use of industrial standard data format in the interface allows our tool to be easily integrated into existing design flow

Automated Segmentation of Cells with IHC Membrane Staining

This study presents a fully automated membrane segmentation technique for immunohistochemical tissue images with membrane staining, which is a critical task in computerized immunohistochemistry (IHC). Membrane segmentation is particularly tricky in immunohistochemical tissue images because the cellular membranes are visible only in the stained tracts of the cell, while the unstained tracts are not visible. Our automated method provides accurate segmentation of the cellular membranes in the stained tracts and reconstructs the approximate location of the unstained tracts using nuclear membranes as a spatial reference. Accurate cell-by-cell membrane segmentation allows per cell morphological analysis and quantification of the target membrane proteins that is fundamental in several medical applications such as cancer characterization and classification, personalized therapy design, and for any other applications requiring cell morphology characterization. Experimental results on real datasets from different anatomical locations demonstrate the wide applicability and high accuracy of our approach in the context of IHC analysi

Forecasting the grid power demand of charging stations from EV drivers’ attitude

In recent years there has been a significant increase in the production of electric vehicles (EVs), in the global strive to reduce polluting gases produced by conventional fossil-fuel driven vehicles. Therefore, many optimization algorithms have been proposed for EV mobility and the charging of battery packs in the stations connected to power grids. However, there are situations in which experimental results are not sufficient, and simulations are needed. In this work, we address the effects of the charge demands of an EV fleet on the grid by considering the attitude of EV drivers, and especially their range anxiety. This influences their decision of when to recharge the battery pack. To this end, an agent-based model has been developed for the simulation of a power grid considering different scenarios based mainly on the state of charge (SOC) of battery packs at the time of the charging requests of EVs at service stations. The results indicate that in general a high battery SOC at the beginning of charging increases the probability of reaching higher power peaks on the grid