11,054 research outputs found

    Economic Analysis and Recommendation of Mobile Virtual Operation Market in China

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    With the continuous development and iteration of telecommunication technology, the users’ requirements of the quality and service have increased dogmatically. In order to meet the diverse and personalized consumer demands, virtual network operators came into being. In 2013, China officially launched mobile wholesale business pilot which symbolized the arrival of virtual operation in China market. This paper explores the economic effect of China virtual operation from the perspective of consumer surplus and social welfare according to the data of data service from three years after the introduction of virtual operation. The results show that, after introducing virtual operators into China market, consumer surplus and social welfare have both enhanced. Moreover, comparing with the wholesale mode, simple virtual operation mode could provide greater consumer surplus and social welfare. At the same time, MVNO will get more profits. In the early stage, MVNO is in a weak position, but the policy of simple virtual operation mode reflects strong government support. Finally, this paper puts forward some recommendations based on the result of the mathematical model and China’s national conditions

    Polydopamine-Coated Manganese Carbonate Nanoparticles for Amplified Magnetic Resonance Imaging-Guided Photothermal Therapy

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    【Abstract】This study reports a multifunctional nanoparticle (NP) with function of amplified magnetic resonance image (MRI)-guided photothermal therapy (PTT) by the surface coating of polydopamine (PDA) shell. Importantly, by means of introducing the surface coating of PDA,it helps entrap large quantities of water around NPs and allow more efficient water exchange, leading to greatly improved MR contrast signals compared with the one without PDA coating. Besides,the distinct photothermal effect can be obtained arising from the strong absorption of PDA in the near-infrared (NIR) region. By synthesizing the multifunctional MnCOs@PDA NPs as example,we found that the longitudinal relaxivity (ri) of MnCOs NPs might improve from 5.7 to 8.3 mM-is-i. Subsequently,In vitro MRI and PTT results verified that MnCOs@PDA could serve well as an excellent MRI/PTT theranostic agent. Furthermore, the MnCO3@PDA nanoparticles were applied as MRI/PTT theranostic agent for in vivo MRI-guided photothermal ablation of tumors by intratumorally injection in 4T1 tumor bearing-mice. The MR imaging result shows a significantly bright MR image in the tumor site. The MnCO3@PDA-mediated PTT result shows high therapy efficiency as a result of their high photothermal conversion efficiency. The present strategy of amplified MRI-guided PTT based on PDA coating on NPs will be widely applicable to other multifunctional nanoparticles.This study was financially supported by the National Natural Science Foundation of China (31271071,31371012,andU1505228)
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