201 research outputs found

    Data_Sheet_1_Differences in the Effects of Reading and Aerobic Exercise Interventions on Inhibitory Control of College Students With Mobile Phone Addiction.CSV

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    Although many previous studies have shown that short-time moderate-intensity aerobic exercise can improve one's inhibitory control, some researchers suggested that its effect on inhibitory control is small. Meanwhile, some studies have shown that reading has a positive effect on inhibitory control. Since many studies examining the effect of exercise on inhibitory control used reading as a filler task, it is important to compare their effects. The present study used the antisaccade task as a tool to examine the differences in the effects of aerobic exercise and reading on inhibitory control of college students with mobile phone addiction. Thirty healthy college students with mobile phone addiction (range: 17–20 years, mean: 19.2 years) took part in the experiment. Participants were randomly assigned to an aerobic exercise group and a reading group. For the aerobic exercise group, participants were asked to perform moderate-intensity aerobic exercise for 15 min. For the reading group, participants were asked to sit quietly and read articles from newspapers for 15 min. Each participant's inhibitory control was examined pre- and post-intervention using the antisaccade task. In the antisaccade task, they have to direct their gaze toward the mirror image location of the target appearing parafoveally as quickly and as accurately as possible. The results showed significant main effects of Time (pre-test vs. post-test) on antisaccade latency and error rate. More importantly, a significant interaction of Time (pre-test vs. post-test) and Group (aerobic exercise vs. reading) was found on antisaccade latency. Specifically, the antisaccade latencies in the post-test were significantly shorter than those in the pre-test for the reading group, but the antisaccade latencies in the post-test and pre-test were comparable for the aerobic exercise group. The results of the present study imply that although both exercise and reading have effects on inhibitory control of college students with mobile phone addiction, the effect of reading may be somehow superior to exercise. Moreover, the current results also imply that researchers should be cautious when using reading as a filler task in future studies regarding the effect of aerobic exercise. The limitations of the present study were discussed.</p

    Data_Sheet_2_Differences in the Effects of Reading and Aerobic Exercise Interventions on Inhibitory Control of College Students With Mobile Phone Addiction.CSV

    No full text
    Although many previous studies have shown that short-time moderate-intensity aerobic exercise can improve one's inhibitory control, some researchers suggested that its effect on inhibitory control is small. Meanwhile, some studies have shown that reading has a positive effect on inhibitory control. Since many studies examining the effect of exercise on inhibitory control used reading as a filler task, it is important to compare their effects. The present study used the antisaccade task as a tool to examine the differences in the effects of aerobic exercise and reading on inhibitory control of college students with mobile phone addiction. Thirty healthy college students with mobile phone addiction (range: 17–20 years, mean: 19.2 years) took part in the experiment. Participants were randomly assigned to an aerobic exercise group and a reading group. For the aerobic exercise group, participants were asked to perform moderate-intensity aerobic exercise for 15 min. For the reading group, participants were asked to sit quietly and read articles from newspapers for 15 min. Each participant's inhibitory control was examined pre- and post-intervention using the antisaccade task. In the antisaccade task, they have to direct their gaze toward the mirror image location of the target appearing parafoveally as quickly and as accurately as possible. The results showed significant main effects of Time (pre-test vs. post-test) on antisaccade latency and error rate. More importantly, a significant interaction of Time (pre-test vs. post-test) and Group (aerobic exercise vs. reading) was found on antisaccade latency. Specifically, the antisaccade latencies in the post-test were significantly shorter than those in the pre-test for the reading group, but the antisaccade latencies in the post-test and pre-test were comparable for the aerobic exercise group. The results of the present study imply that although both exercise and reading have effects on inhibitory control of college students with mobile phone addiction, the effect of reading may be somehow superior to exercise. Moreover, the current results also imply that researchers should be cautious when using reading as a filler task in future studies regarding the effect of aerobic exercise. The limitations of the present study were discussed.</p

    Image1_Comprehensive Analysis of the Expression and Prognosis for the DREAM Complex in Human Cancers.jpg

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    The DREAM complex is an evolutionarily conserved cell cycle regulating multi-protein complex. In addition to playing an essential function in the cell cycle, it also plays a vital role in various survival activities. Accumulating evidence suggests that the DREAM complex plays a crucial role in oncogenesis. However, the regulatory mechanism of the DREAM complex in cancer remains unclear. This study used multi-omics data from Cancer Genome Atlas and Cancer Cell Line Encyclopedia to comprehensively identify the DREAM complex in tumor samples from 33 cancer types. In the genomic landscape, we identified the missense mutation as the dominant alteration events. Expression analysis showed that the expression of methylation-mediated the DREAM complex was downregulated. In addition, we found that the expression of the DREAM complex can be performed to predict the survival of various cancer patients. Pathway activation analysis showed that the DREAM complex is related to apoptosis inhibition, cell cycle, DNA damage response, RAS/MAPK, and RTK signaling pathway activation. Importantly, through a comprehensive analysis of drug sensitivity genomics in cancer databases, we identified a number of potential drugs that may target the DREAM complex. In summary, this study revealed the genomic changes and clinical features of the DREAM complex in 33 cancers, which may also provide new insights for cancer treatment and may offer alternative options for the treatment of clinically refractory cancers.</p

    MYOARTICULAR RECOVERY AFTER KUNG FU TRAINING

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    ABSTRACT Introduction Kung fu is a Chinese martial art with continuous movements based on step movement and embodied by the transformation of body shapes, requiring the athletes to strengthen the lower limbs. Joint and muscle analysis are critical to verify the strength of athletes’ lower limbs and play a guiding role in evaluating the level of recovery for injured athletes. Objective Explore the myoarticular recovery effect after kung fu training. Methods 24 kung fu athletes were randomly divided into experimental and control groups, with 6 males and 6 females in each group. The athletes in the experimental group received traditional martial training for 60 minutes, while the control group received relaxation training simultaneously. The experiment lasted for 6 months and was performed 6 times a month. Results After kung fu training, the rates of the experimental group were higher than those of the control group. Conclusion Kung fu training positively impacts the athletes’ muscle strength and joint strength. Kung fu training can also improve the level of myoarticular recovery and improve the flexibility of its practitioners. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.</div

    Image2_Comprehensive Analysis of the Expression and Prognosis for the DREAM Complex in Human Cancers.jpg

    No full text
    The DREAM complex is an evolutionarily conserved cell cycle regulating multi-protein complex. In addition to playing an essential function in the cell cycle, it also plays a vital role in various survival activities. Accumulating evidence suggests that the DREAM complex plays a crucial role in oncogenesis. However, the regulatory mechanism of the DREAM complex in cancer remains unclear. This study used multi-omics data from Cancer Genome Atlas and Cancer Cell Line Encyclopedia to comprehensively identify the DREAM complex in tumor samples from 33 cancer types. In the genomic landscape, we identified the missense mutation as the dominant alteration events. Expression analysis showed that the expression of methylation-mediated the DREAM complex was downregulated. In addition, we found that the expression of the DREAM complex can be performed to predict the survival of various cancer patients. Pathway activation analysis showed that the DREAM complex is related to apoptosis inhibition, cell cycle, DNA damage response, RAS/MAPK, and RTK signaling pathway activation. Importantly, through a comprehensive analysis of drug sensitivity genomics in cancer databases, we identified a number of potential drugs that may target the DREAM complex. In summary, this study revealed the genomic changes and clinical features of the DREAM complex in 33 cancers, which may also provide new insights for cancer treatment and may offer alternative options for the treatment of clinically refractory cancers.</p

    Extended Mo<sub>3</sub><sup>IV</sup>-Polyoxometalates: 1D-[Mo<sub>6</sub><sup>IV</sup>Mo<sub>4</sub><sup>VI</sup>Ge<sub>2</sub>ZnO<sub>31</sub>py<sub>9</sub> (H<sub>2</sub>O)]<sup>4–</sup> and 2D-[Mo<sub>3</sub><sup>IV</sup>Mo<sub>9</sub><sup>VI</sup>Zn<sub>6</sub>P<sub>7</sub>O<sub>56</sub>py<sub>8</sub>]<sup>+</sup> (py = Pyridine)

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    The first examples of extended Mo3IV-polyoxometalates (Mo3IV-POMs), 1D-H2 [Ge2Mo6IVMo4VIO31Zn­(H2O)­py9]·2Hpy·HOCH2CH2 OH•4H2O­(H2[1]·2Hpy•glycol·H2O) and 2D-[P@Mo3IVMo9VIZn6(PO4)6O32py8]­Cl·2py·7H2O ([2]·Cl•2py·7H2O), were prepared through the solvothermal partial oxidation of [Mo3IVO2(O2CCH3)6(H2O)3]­ZnCl4 in py/H2O containing glycol (for 1) or H3PO4 (for 2). They were characterized by X-ray crystallography and elemental analyses. Their electronic structure and bonding were discussed on the basis of density functional theory (DFT) theoretical calculations. X-ray photoelectron spectroscopy, IR/UV–vis spectra, powder X-ray diffraction, thermal gravimetric analysis, and mass spectrometry were also performed and discussed for 2D-2

    Iron-Catalyzed C(sp<sup>3</sup>)–H Acyloxylation of Aryl‑2<i>H</i> Azirines with Hypervalent Iodine(III) Reagents

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    This letter describes an iron-catalyzed C­(sp<sup>3</sup>)–H acyloxylation of aryl-2<i>H</i> azirines with hypervalent iodine­(III) reagents (HIRs) serving as both an oxidant and a reagent. This methodology provides a rapid access to a wide range of monoacyloxylated 3-aryl-2<i>H</i>-azirines in moderate to good yields

    Rayleigh Instability Induced Cylinder-to-Sphere Transition in Block Copolymer Micelles: Direct Visualization of the Kinetic Pathway

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    Direct visualization of morphological evolution remains extremely challenging despite its critical importance to understand the basic fundamentals behind the transition. Here we report on the detailed observation of a spontaneous cylinder-to-sphere morphological transformation of amphiphilic poly­(2-vinylpyridine)-<i>b</i>-poly­(ethylene oxide) (P2VP-<i>b</i>-PEO) diblock copolymer micelles in aqueous solution, which first provides experimental evidence that the fragmentation pathway is driven by Rayleigh instability showing the distinctive signatures during the transition. Owing to the instability of cylindrical micelles and the fluidity of micellar cores, our results show that the cylindrical micelles spontaneously undulate and transform into spherical micelles through distinct intermediate states, including undulated cylinders and pearl-necklace-like micelles with a perfect sinusoidal wave throughout the length. Moreover, the present system with transitional morphology is proved to be able to act as a model to encapsulate hydrophobic guests in the micellar cores, which displays a relatively sustained release behavior. The specific kinetic pathway provides new insight into the mechanism of block copolymer micellar morphological transition; meanwhile, the dynamic system might serve as a promising candidate for unique nanostructure design as well as contribute to the transition-coupled guest delivery and controlled release

    Visible-Light Photoredox-Catalyzed Regioselective Sulfonylation of Alkenes Assisted by Oximes via [1,5]‑H Migration

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    We herein report a visible-light photoredox-catalyzed regioselective sulfonylation of alkenes with sulfonyl hydrazides assisted by oximes at room temperature, which affords a variety of sulfones in good yields. The initial mechanistic experiments demonstrate that the hydroxyl group within oximes plays a crucial role in this sulfonylation
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