387 research outputs found

    The Semantic Automated Discovery and Integration (SADI) Web service Design-Pattern, API and Reference Implementation

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    Background. 
The complexity and inter-related nature of biological data poses a difficult challenge for data and tool integration. There has been a proliferation of interoperability standards and projects over the past decade, none of which has been widely adopted by the bioinformatics community. Recent attempts have focused on the use of semantics to assist integration, and Semantic Web technologies are being welcomed by this community.

Description. 
SADI – Semantic Automated Discovery and Integration – is a lightweight set of fully standards-compliant Semantic Web service design patterns that simplify the publication of services of the type commonly found in bioinformatics and other scientific domains. Using Semantic Web technologies at every level of the Web services “stack”, SADI services consume and produce instances of OWL Classes following a small number of very straightforward best-practices. In addition, we provide codebases that support these best-practices, and plug-in tools to popular developer and client software that dramatically simplify deployment of services by providers, and the discovery and utilization of those services by their consumers.

Conclusions.
SADI Services are fully compliant with, and utilize only foundational Web standards; are simple to create and maintain for service providers; and can be discovered and utilized in a very intuitive way by biologist end-users. In addition, the SADI design patterns significantly improve the ability of software to automatically discover appropriate services based on user-needs, and automatically chain these into complex analytical workflows. We show that, when resources are exposed through SADI, data compliant with a given ontological model can be automatically gathered, or generated, from these distributed, non-coordinating resources - a behavior we have not observed in any other Semantic system. Finally, we show that, using SADI, data dynamically generated from Web services can be explored in a manner very similar to data housed in static triple-stores, thus facilitating the intersection of Web services and Semantic Web technologies

    The Watchers of the Water

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    Common Lower Extremity Injury Sites Among Service Members and Combat Sport Athletes: A Systematic Review

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    Title: Common Lower Extremity Injury Sites Among Service Members and Combat Sport Athletes: A Systematic Review Luke McCarthy, Tyler Hansen, Shane Murphy Purpose: Athletic training services continue to expand into nontraditional settings, with a substantial growth in treating military service members and combat sport athletes (e.g., tae kwon do, MMA, karate). Although more athletic trainers are asked to work with these populations, location and frequency of injuries within these populations is not widely disseminated in athletic training education curriculum. This systematic review was conducted to discover if common injury sites exist between service members and combat sport athletes. We hypothesized that the two cohorts shared many common injury sites, though the mechanism of injury would likely be different. Methods: A systematic review of studies between 2008 and 2020 were examined via PubMed in October of 2020. Key words used in the search include population (e.g. military OR martial arts OR MMA), anatomical area (e.g., lower extremity OR LE), and injury occurrence rate; returning 76 articles. Two independent reviewers utilized a PRISMA flowchart to select the articles to be included in the final analysis. The level of evidence was initially assessed for all included articles, with no uncontrolled cohort studies, case series, or expert opinions being included in the final analysis. Studies that did not identify injury sites were excluded, with only studies providing lower extremity injury site and frequency being selected. Injury site and frequency were extracted from articles focusing on either service members or combat sport athletes. Originality: This research is novel, in that it provides athletic trainers in these emerging settings the ability to forecast what injuries they are most likely to encounter, given the setting (e.g., training, competition, and combat). Each of these settings, as well as the age and skill level of the athletes involves different injury types (chronic versus acute). During the systematic review, there were no articles found comparing military service members and combat sport athletes. Significances: As more athletic trainers begin working in these emerging settings, knowledge about how each cohort sustains their injuries will be important. Being able to treat injuries when they occur, as well as prevent injuries from happening, will reduce the amount of time lost to rehabilitation. This increased time in rehabilitation translates to increased medical costs and strain on our healthcare system as a whole. Preventing injuries will reduce medical spending both for the individual athletes and for the federal/state government, in the case of service members. Service members and combat sport athletes sustain lower extremity injuries at both the ankle and knee; however, they differ in general mechanism. Due to the stresses of prolonged load carriage versus forceful striking, clinicians will face unique challenges working with either population. By understanding the environment service members and combat athletes are operating in, athletic trainers can have necessary supplies on hand for treatment of acute injuries, as well as plans to rehabilitate chronic injuries. Future research should focus on methods of reducing acute injuries in combat sports and more effective chronic injury prevention among service members

    Organizational and formational structures of networks in the mental lexicon: A State-of-the-art through systematic review

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    This state-of-the-art presents a systematic exploration on the use of network patterns in global research efforts to understand, organize and represent the mental lexicon. Results have shown an increase over recent years in the usage of complex, small-world and scale-free network patterns within the literature.With the increasing complexity of network patterns, we see more potential in the inter-disciplinary exploration of the mental lexicon through universal and mathematically-describable, behavioral patterns in small-world and scale-free networks. A systematic review of 36 items of methodologically-selected literature serve as a means to explore how the greater literary body understands network structures within the mental lexicon. Network-based approaches are discriminated between three contrasting varieties. These include: 'simple networks', characterized by arbitrarily organized graph patterns of metaphorical importance; 'connectionist networks', a broad category of networks which explore the structural features of a system through the analysis of emergent properties; and lastly 'complex networks', distinguished as small-world, scale-free networks which follow a strict and mathematically-describable structure in agreement with the Barabási-Albert model. Each network approach is explored in terms of their discernible di erences which relate to their parameters and affect their implications. A final evaluation of observed patterns within the selected literature is o ered, as well as an elaboration on the sense of trajectory beheld in the research in order to offer insight and orientation for future research

    Effects of Art from the Heart on Nurse Satisfaction and Patient Well-Being

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    Introduction. Art programs have been shown to positively affect unit culture, quality of care, and nursing practices. Art interventions improve well-being, reduce stress, and enhance nurse-patient communication. Art from the Heart (AFTH) is an art program that provides art supplies, visual art, and patient About Me pages to patients, families and employees at University of Vermont Medical Center (UVMMC).Objective. Assess the efficacy of AFTH through nursing staff perceptions, understanding, and attitudes toward the program.Methods. Structured interviews were conducted on Baird 4, an adult inpatient ward, at UVMMC. A 19-question survey using Likert scales and short answer formats was administered to nursing staff. Questions assessed perceptions of effects of art on patient anxiety and pain, communication, and job satisfaction. Surveys were analyzed to extract major and minor themes.Results. Twenty-eight interviews were obtained and two major themes emerged: nurse satisfaction and patient well-being. Nursing staff satisfaction minor themes included improved productivity, promoting conversation, and creating a positive influence on the unit. Respondents reported that AFTH helped initiate conversations with patients (100% of respondents) and reduced workday stress (68%). The second major theme, patient well-being, included benefits to patients with dementia, providing comfort, and serving as an outlet or distraction. Utilizing AFTH improved perceived patient mood (100%), health (78.5%), and reduced patient anxiety (89.3%).Conclusions. AFTH provides positive benefits by reducing nursing staff stress and perceived patient anxiety; improving communication, perceived patient mood and health; and creating a sense of community. AFTH should be expanded to the entire 6 Community Agency: Burlington City Arts, Art from the Hearthttps://scholarworks.uvm.edu/comphp_gallery/1240/thumbnail.jp

    SPARQL Assist Language Neutral Query Composer

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    SPARQL query composition is difficult for the lay-person or even the experienced bioinformatician in cases where the data model is unfamiliar. Established best-practices and internationalization concerns dictate that semantic web ontologies should use terms with opaque identifiers, further complicating the task. We present SPARQL Assist: a web application that addresses these issues by providing context-sensitive type-ahead completion to existing web forms. Ontological terms are suggested using their labels and descriptions, leveraging existing XML support for internationalization and language-neutrality

    Effect of ethnicity on live birth rates after in vitro fertilisation/intracytoplasmic sperm injection treatment: analysis of UK national database

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    Objective To evaluate the effect of ethnicity of women on the outcome of in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) treatment. Design Observational cohort study. Setting UK National Database. Population Data from 2000 to 2010 involving 38 709 women undergoing their first IVF/ICSI cycle were analysed. Methods Anonymous data were obtained from the Human Fertilization and Embryology Authority (HFEA), the statutory regulator of IVF and ICSI treatment in the UK. Data analysis was performed by regression analysis with adjustment for age, cause and type of infertility and treatment type (IVF or ICSI) to express results as odds ratio (OR) and 95% confidence intervals (95% CI). Methods Live birth rate per cycle of IVF or ICSI treatment. Results While white Irish (OR 0.73; 95% CI 0.60–0.90), Indian (0.85; 0.75–0.97), Bangladeshi (0.53: 0.33–0.85), Pakistani (0.68; 0.58–0.80), Black African (0.60; 0.51–0.72), and other non-Caucasian Asian (0.86; 0.73–0.99) had a significantly lower odds of live birth rates per fresh IVF/ICSI cycle than White British women, ethnic groups of White European (1.04; 0.96–1.13), Chinese (1.12; 0.77–1.64), Black Caribbean (0.76; 0.51–1.13), Middle Eastern (0.73; 0.51–1.04), Mediterranean European (1.18; 0.83–1.70) and Mixed race population (0.94; 0.73–1.19) had live birth rates that did not differ significantly. The cumulative live birth rates showed similar patterns across different ethnic groups. Conclusion Ethnicity is a major determinant of IVF/ICSI treatment outcome as indicated by significantly lower live birth rates in some of the ethnic minority groups compared with white British women
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