Locations of the sequenced segments and LD distribution in the <i>CDH2</i> gene.

<p>(A) Schematic map of the locations of the 9 sequenced segments in the <i>CDH2</i> gene region. (B) LD distribution in the <i>CDH2</i> gene in the BM population. Location to the LD Blocks in the BM (BM Blocks) is indicated in Fig. 1B.</p

The distribution of three population genetic statistics and the information of coalescent simulations.

<p>(A) Distribution of Tajima's D values for the 9 segments of the <i>CDH2</i> gene region in the BM and CID populations. (B) Standard coalescent simulations under a neutral model for the genealogy of the BM. Part I is the genealogy of BM and parts II-IV are standard coalescent simulations for segments S4, S5, S6, respectively, under different values for N5 (50,000 and 100,000) in the BM population. P_mean is the mean of the P values for the Tajima D test. (C) SNP heterozygosity distribution in the <i>CDH2</i> gene region in the BM and CID populations. (D) Frequency distribution of heterozygotes for each SNP in the BM and CID populations.</p

Median-joining network showing the genealogy of the BM Block 3 haplotypes in the BM population.

<p>Each haplotypes is shown as a circle with the size of the circle representing the haplotype frequency. Nucleotide differences between haplotypes are shown on the branches of the network.</p

Polymorphism statistics and neutral tests in both the BM and CID populations.

<p>Note:</p>1<p> The number of chromosome; ² Number of segregating sites; ³ Nucleotide diversity.</p><p>Polymorphism statistics and neutral tests in both the BM and CID populations.</p