Summary of clinical characteristics in IDH1 mutation patient.

<p>Summary of clinical characteristics in IDH1 mutation patient.</p

Genetic alterations in AML patients with/without <i>IDH1</i> mutations.

<p>Genetic alterations in AML patients with/without <i>IDH1</i> mutations.</p

Patient demographics, clinical data and cytogenetic changes in AML patients with/without <i>IDH1</i> mutations.

<p>Patient demographics, clinical data and cytogenetic changes in AML patients with/without <i>IDH1</i> mutations.</p

Survival curve of AML patients.

<p>Kaplan-Meier curve shows OS (A) in patients with IDH1non-R132 mutations and IDH1 wild type. The OS (B) in patients with non-R132 IDH1 mutations who were transplanted or non-transplanted.</p

DNA sequencing of <i>IDH1</i> mutations.

<p>DNA sequencing chromatograms of representative heterozygous <i>IDH1</i> mutations and reference wild type <i>IDH1</i>.</p

Incidence of different subtypes of <i>IDH1</i> mutations.

<p>Eight <i>IDH1</i> mutations were detected in 35/349 patients.</p