2 research outputs found
Gallium Analogue of Soluble Prussian Blue KGa[Fe(CN)<sub>6</sub>]路<i>n</i>H<sub>2</sub>O: Synthesis, Characterization, and Potential Biomedical Applications
No full textThe
gallium analogue of the soluble Prussian blue with the formula KGa颅[Fe颅(CN)<sub>6</sub>]路<i>n</i>H<sub>2</sub>O is synthesized and
structurally characterized. A simple aqueous synthetic procedure for
preparing nanoparticles of this novel coordination polymer is reported.
The stability, in vitro ion exchange with ferrous ions, cytotoxicity,
and cellular uptake of such nanoparticles coated with poly颅(vinylpyrrolidone)
are investigated for potential applications of delivering Ga<sup>3+</sup> ions into cells or removing iron from cells
Biocompatible Nanoparticles of KGd(H<sub>2</sub>O)<sub>2</sub>[Fe(CN)<sub>6</sub>]路H<sub>2</sub>O with Extremely High <i>T</i><sub>1</sub>鈥慦eighted Relaxivity Owing to Two Water Molecules Directly Bound to the Gd(III) Center
No full textA simple one-step method for preparing
biocompatible nanoparticles of gadolinium ferrocyanide coordination
polymer KGd颅(H<sub>2</sub>O)<sub>2</sub>[Fe颅(CN)<sub>6</sub>]路H<sub>2</sub>O is reported. The crystal structure of this coordination
polymer is determined by X-ray powder diffraction using the bulk materials.
The stability, cytotoxicity, cellular uptake, and MR phantom and cellular
imaging studies suggest that this coordination-polymer structural
platform offers a unique opportunity for developing the next generation
of <i>T</i><sub>1</sub>-weighted contrast agents with high
relaxivity as cellular MR probes for biological receptors or markers.
Such high-relaxivity MR probes may hold potential in the study of
molecular events and may be used for in vivo MR imaging in biomedical
research and clinical applications
