Pengaruh Kepemimpinan dan Komunikasi Kepala Desa terhadap Partisipasi Masyarakat dalam Pembangunan Desa Taikako Kecamatan Sikakap Kabupaten Kepulauan Mentawai

Penelitian ini bertujuan untuk menganalisis : 1) Pengaruh Gaya Kepemimpinan Kepala Desa Taikako Terhadap Partisipasi Masyarakat Dalam Pembangunan Desa Taikako Kecamatan Sikakap Kabupaten Kepulauan Mentawai, 2) Pengaruh Komunikasi Kepala Desa Taikako Terhadap Partisipasi Masyarakat Dalam Pembangunan Desa Taikako Kecamatan Sikakap Kabupaten Kepulauan Mentawai, 3) Pengaruh Gaya Kepemimpinan dan komunikasi Kepala Desa Taikako secara bersama-sama Terhadap Partisipasi Masyarakat Dalam Pembangunan Desa Taikako Kecamatan Sikakap Kabupaten Kepulauan Mentawai. Waktu penelitian adalah bulan September 2014. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian deskriptif asosiatif. Yang menjadi sampel adalah KK yang bertempat tinggal di Desa Taikako sebesar 100 KK.Teknik analisis data yang dilakukan adalah analisis deskriptif dan analisis induktif, yaitu uji likelihood,uji ramsey, uji normalitas, uji multikoleniaritas, uji heteroskedastisitas, uji autokorelasi dan analisis regresi berganda dengan bantuan program SPSS versi 16.0. Berdasarkan hasil penelitian, maka Gaya kepemimpinan secara parsial berpangaruh negatif terhadap partisipasi yang dilihat dari nilai koefisien -0.829 signifikan pada nilai thitung sebesar 2,958 > ttabel sebesar 1,657 dengan signifikansi 0,004 ttabel sebesar 1,657 dan nilai signifikansi 0,000 Ftabel sebesar 3,07 dan nilai signifikansi 0,000 < 0,05. Artinya semakin tinggi Gaya kepemimpinan dan komunikasi maka Persepsi atas partisipasi semakin tinggi juga dan sebaliknya. Adapun besarnya kontribusi yang diberikan variabel X terhadap variabel Y adalah sebesar 78,2%. Sedangkan sisanya 21,8% dipengaruhi oleh variabel lain yang tidak termasuk dalam penelitian ini

Top physic results from ATLAS and CMS

In this paper a summary of some of the latest and most precise measurements in the top quark physics field performed by the ATLAS and CMS experiments are presented. These include the most precise measurements for t¯t and single top cross-section as well as for the top mass, but also various measurements of top production and decay. Higgs and New Physics searches in the top quark Sector are not reported here

Very Constrained Minimal Supersymmetric Standard Models

We consider very constrained versions of the minimal supersymmetric extension of the Standard Model (VCMSSMs) which, in addition to constraining the scalar masses m_0 and gaugino masses m_{1/2} to be universal at some input scale, impose relations between the trilinear and bilinear soft supersymmetry breaking parameters A_0 and B_0. These relations may be linear, as in simple minimal supergravity models, or nonlinear, as in the Giudice-Masiero mechanism for generating the Higgs-mixing mu term. We discuss the application of the electroweak vacuum conditions in VCMSSMs, which may be used to make a prediction for tan beta as a function of m_0 and m_{1/2} that is usually unique. We baseline the discussion of the parameter spaces allowed in VCMSSMs by updating the parameter space allowed in the CMSSM for fixed values of tan beta with no relation between A_0 and B_0 assumed {\it a priori}, displaying contours of B_0 for a fixed input value of A_0, incorporating the latest CDF/D0 measurement of m_t and the latest BNL measurement of g_mu - 2. We emphasize that phenomenological studies of the CMSSM are frequently not applicable to specific VCMSSMs, notably those based on minimal supergravity, which require m_0 = m_{3/2} as well as A_0 = B_0 + m_0. We then display (m_{1/2}, m_0) planes for selected VCMSSMs, treating in a unified way the parameter regions where either a neutralino or the gravitino is the LSP. In particular, we examine in detail the allowed parameter space for the Giudice-Masiero model.Comment: 26 pages, 32 eps figure

Spontaneous immunogenicity of ribosomal P0 protein in patients with benign and malignant breast lesions and delay of mammary tumor growth in P0-vaccinated mice

A common carboxyl-terminal epitope (C-22 P0) of the ribosomal P proteins (P0, P1 and P2) was shown to elicit autoantibodies in systemic lupus erythematosus (SLE) and in head and neck cancer patients. In this report we provide evidence for the in vivo immunogenicity of the P0 protein in breast cancer patients. Using recombinant P proteins, we demonstrated that sera from breast carcinoma patients (8/75) displayed significant reactivity to P0 protein when compared with healthy donor sera (0/45). Four out of the eight sera showed simultaneous reactivity to all P proteins. Breast benign tumor (3/17) and mammary hyperplasia (3/17) patient sera also showed significant reactivity to P proteins, thus suggesting that the occurrence of P protein autoantibodies might reveal mammary cell cycle dysregulation. Patient sera reacting with all P proteins recognized C-22 P0. Anti-P0 autoantibodies did not correlate with prognostic parameters of breast carcinomas. High level expression of C-22 P0 was found in mammary carcinomas compared with normal adjacent epithelium and benign lesions. To determine the antitumor activity of P0 as an immunogen, BALB-neuT transgenic mice displaying age-related breast cancer progression were vaccinated using xenogeneic P0 at the stage of mammary atypical hyperplasia. P0 vaccination significantly delayed the onset of mouse mammary tumors that overexpressed C-22 P0. Sera from P0 vaccinated mice recognized C-22 P0. Evidence for immunity to the P0 protein, its overexpression in carcinomas and its peculiar surface localization on cancer cells, along with its antitumor activity as an immunogen might be relevant for the use of P0 protein in monitoring cancer progression and in planning immunotherapeutic strategies

Constraining Supersymmetry

We review constraints on the minimal supersymmetric extension of the Standard Model (MSSM) coming from direct searches at accelerators such as LEP, indirect measurements such as b -> s gamma decay and the anomalous magnetic moment of the muon. The recently corrected sign of pole light-by-light scattering contributions to the latter is taken into account. We combine these constraints with those due to the cosmological density of stable supersymmetric relic particles. The possible indications on the supersymmetric mass scale provided by fine-tuning arguments are reviewed critically. We discuss briefly the prospects for future accelerator searches for supersymmetry.Comment: 21 LaTeX pages, 9 eps figures, Invited Contribution to the New Journal of Physics Focus Issue on Supersymmetr

Optimization of Italian CMS Computing Centers via MIUR funded Research Projects

In 2012, 14 Italian Institutions participating LHC Experiments (10 in CMS) have won a grant from the Italian Ministry of Research (MIUR), to optimize Analysis activities and in general the Tier2/Tier3 infrastructure. A large range of activities is actively carried on: they cover data distribution over WAN, dynamic provisioning for both scheduled and interactive processing, design and development of tools for distributed data analysis, and tests on the porting of CMS software stack to new highly performing / low power architectures

Determining Supersymmetric Parameters With Dark Matter Experiments

In this article, we explore the ability of direct and indirect dark matter experiments to not only detect neutralino dark matter, but to constrain and measure the parameters of supersymmetry. In particular, we explore the relationship between the phenomenological quantities relevant to dark matter experiments, such as the neutralino annihilation and elastic scattering cross sections, and the underlying characteristics of the supersymmetric model, such as the values of mu (and the composition of the lightest neutralino), m_A and tan beta. We explore a broad range of supersymmetric models and then focus on a smaller set of benchmark models. We find that by combining astrophysical observations with collider measurements, mu can often be constrained far more tightly than it can be from LHC data alone. In models in the A-funnel region of parameter space, we find that dark matter experiments can potentially determine m_A to roughly +/-100 GeV, even when heavy neutral MSSM Higgs bosons (A, H_1) cannot be observed at the LHC. The information provided by astrophysical experiments is often highly complementary to the information most easily ascertained at colliders.Comment: 46 pages, 76 figure

Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity

The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole-exome sequencing data of about 4000 SARS-CoV-2-positive individuals were used to define an interpretable machine-learning model for predicting COVID-19 severity. First, variants were converted into separate sets of Boolean features, depending on the absence or the presence of variants in each gene. An ensemble of LASSO logistic regression models was used to identify the most informative Boolean features with respect to the genetic bases of severity. The Boolean features selected by these logistic models were combined into an Integrated PolyGenic Score that offers a synthetic and interpretable index for describing the contribution of host genetics in COVID-19 severity, as demonstrated through testing in several independent cohorts. Selected features belong to ultra-rare, rare, low-frequency, and common variants, including those in linkage disequilibrium with known GWAS loci. Noteworthily, around one quarter of the selected genes are sex-specific. Pathway analysis of the selected genes associated with COVID-19 severity reflected the multi-organ nature of the disease. The proposed model might provide useful information for developing diagnostics and therapeutics, while also being able to guide bedside disease management