Schaetzung der Verkehrsbeziehungen bei unvollstaendiger Information und deren Anwendung bei der Verkehrssteuerung

Available from TIB Hannover: F02B909 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

Additional file 1 of Community-embedded follow-up management intervention for geriatric primary care: a mixed-methods study of an integrated health services model

Supplementary Material

Immunotoxic effect of arsenic trioxide on <i>Caenorhabditis elegans</i>

<div><p>A <i>Pseudomonas aeruginosa</i>–<i>Caenorhabditis elegans</i> pathogenesis model was utilized to assess immunotoxic effects of arsenic trioxide (As₂O₃). After 2 h of As₂O₃ exposure, 500 µmol L⁻¹ and 1 mmol L⁻¹ As₂O₃ treatment significantly decreased median survivals of <i>C. elegans</i> (10 h after L4/adult molt). However, 2 h of As₂O₃ exposure caused no significant changes in the survivals rates of <i>C. elegans</i> (2 h after L4/adult molt). Notably, a significant dose-related immunoenhancement was observed in <i>C. elegans</i> (2 h after L4/adult molt) after 12 h of arsenite exposure.</p></div

Data_Sheet_1_Transcriptomic analysis of the response of Avena sativa to Bacillus amyloliquefaciens DGL1.PDF

IntroductionBacillus amyloliquefaciens DGL1, isolated from the arid sandy areas in Dagler, Qinghai Province, China, promotes the growth of Avena sativa variety “Qing Yan 1”.MethodsTo elucidate the transcriptomic changes in the oat root system following interaction with DGL1 and to reveal the molecular mechanism by which DGL1 promotes oat growth, treatment and control groups of oat roots at 2, 4, 8, and 12 h after inoculation with a suspension of strain DGL1 were analyzed using Illumina high-throughput transcriptome sequencing technology. The differentially expressed genes were determined through Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses, and the metabolic pathways and key genes were analyzed.ResultsThe results showed that 7874, 13,392, 13,169, and 19,026 differentially expressed genes were significantly enriched in the glycolysis/gluconeogenesis pathway, amino acid metabolism, nitrogen metabolism, plant hormone signal transduction, and other related metabolic pathways in the oat roots at 2, 4, 8, and 12 h after inoculation with a DGL1 suspension. The GO and KEGG enrichment analyses revealed that the genes encoding plasma membrane ATPase, phosphoglycerate kinase gene PGK, ammonium transporter protein gene AMT, cellulose synthase gene CSLF6, and growth hormone response family gene IAA18 were significantly upregulated.DiscussionIt is hypothesized that the pro-growth mechanism of strain DGL1 in oats is the result of the coordination of multiple pathways through the promotion of oat energy metabolism, phytohormone signaling, secondary metabolite synthesis, and amino acid metabolism.</p

Image_1_Transcriptomic analysis of the response of Avena sativa to Bacillus amyloliquefaciens DGL1.pdf

IntroductionBacillus amyloliquefaciens DGL1, isolated from the arid sandy areas in Dagler, Qinghai Province, China, promotes the growth of Avena sativa variety “Qing Yan 1”.MethodsTo elucidate the transcriptomic changes in the oat root system following interaction with DGL1 and to reveal the molecular mechanism by which DGL1 promotes oat growth, treatment and control groups of oat roots at 2, 4, 8, and 12 h after inoculation with a suspension of strain DGL1 were analyzed using Illumina high-throughput transcriptome sequencing technology. The differentially expressed genes were determined through Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses, and the metabolic pathways and key genes were analyzed.ResultsThe results showed that 7874, 13,392, 13,169, and 19,026 differentially expressed genes were significantly enriched in the glycolysis/gluconeogenesis pathway, amino acid metabolism, nitrogen metabolism, plant hormone signal transduction, and other related metabolic pathways in the oat roots at 2, 4, 8, and 12 h after inoculation with a DGL1 suspension. The GO and KEGG enrichment analyses revealed that the genes encoding plasma membrane ATPase, phosphoglycerate kinase gene PGK, ammonium transporter protein gene AMT, cellulose synthase gene CSLF6, and growth hormone response family gene IAA18 were significantly upregulated.DiscussionIt is hypothesized that the pro-growth mechanism of strain DGL1 in oats is the result of the coordination of multiple pathways through the promotion of oat energy metabolism, phytohormone signaling, secondary metabolite synthesis, and amino acid metabolism.</p

Map of the sampling locations in the Yangtze River estuary.

<p>Map of the sampling locations in the Yangtze River estuary.</p

Table_1_Transcriptomic analysis of the response of Avena sativa to Bacillus amyloliquefaciens DGL1.xlsx

IntroductionBacillus amyloliquefaciens DGL1, isolated from the arid sandy areas in Dagler, Qinghai Province, China, promotes the growth of Avena sativa variety “Qing Yan 1”.MethodsTo elucidate the transcriptomic changes in the oat root system following interaction with DGL1 and to reveal the molecular mechanism by which DGL1 promotes oat growth, treatment and control groups of oat roots at 2, 4, 8, and 12 h after inoculation with a suspension of strain DGL1 were analyzed using Illumina high-throughput transcriptome sequencing technology. The differentially expressed genes were determined through Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses, and the metabolic pathways and key genes were analyzed.ResultsThe results showed that 7874, 13,392, 13,169, and 19,026 differentially expressed genes were significantly enriched in the glycolysis/gluconeogenesis pathway, amino acid metabolism, nitrogen metabolism, plant hormone signal transduction, and other related metabolic pathways in the oat roots at 2, 4, 8, and 12 h after inoculation with a DGL1 suspension. The GO and KEGG enrichment analyses revealed that the genes encoding plasma membrane ATPase, phosphoglycerate kinase gene PGK, ammonium transporter protein gene AMT, cellulose synthase gene CSLF6, and growth hormone response family gene IAA18 were significantly upregulated.DiscussionIt is hypothesized that the pro-growth mechanism of strain DGL1 in oats is the result of the coordination of multiple pathways through the promotion of oat energy metabolism, phytohormone signaling, secondary metabolite synthesis, and amino acid metabolism.</p

Mutagenic activity of three fractions of samples Y2, Y7, Y8 and Y9.

<p>Mutagenicity measured by the Ames fluctuation assay using TA98 bacteria with and without bioactivation enzymes (S9). Mutagenic activity is expressed as maximum induction factor within the dose-response curve.</p

Mutagenic activity of nine sediment extracts from Yangtze River estuary.

<p>Mutagenic measured by the Ames fluctuation assay using both TA98 and TA100 bacteria strain with and without bioactivation enzymes (S9). TA100 with or without S9 is not shown because no mutagenic effects were observed in any of the samples. Data are shown as maximum induction factor (IF_max) as the highest IF score of a particular sample within the dose-response curve. Multiple symbols indicate different significant levels relative to the negative control (NC): *<i>p</i><0.05, **<i>p</i><0.01.</p

Content of total organic carbon (TOC) (%) and concentrations of the 16 US EPA-polycyclic aromatic hydrocarbons (PAHs) (ng/g dw) in sediment samples from the Yangtze River estuary.

<p>Note: The data of PAHs were obtained from Liu et al. (2014). n.d. = not detectable or below the detection limit.</p><p>Content of total organic carbon (TOC) (%) and concentrations of the 16 US EPA-polycyclic aromatic hydrocarbons (PAHs) (ng/g dw) in sediment samples from the Yangtze River estuary.</p