Regeneration of the Waste Selective Catalytic Reduction Denitrification Catalyst by Nitric Acid Washing

In this study, the waste V2O5–WO3/TiO2 denitrification catalysts from the coal-fired power plant were washed with water or nitric acid, followed by impregnating different contents of V2O5. The effects of the HNO3 concentration and the additional amount of vanadium on the low-temperature selective catalytic reduction denitrification activity were investigated under the condition of high concentration of SO2 and H2O. The catalysts were characterized by inductively coupled plasma optical emission spectrometry, X-ray powder diffraction , N2 adsorption/desorption, H2-temperature-programmed reduction, NH3-temperature-programmed desorption , Fourier transform infrared spectroscopy , and Raman spectroscopy. The evaluation results revealed that optimum activity was achieved by using 0.8 mol/L HNO3 solution and loading 1.60 wt % V2O5 to make the total V2O5 reach 2.3 wt %. The characterization results showed that nitric washing can remove most of the ammonium salts deposited on the surface of the waste catalyst and produce crystalline WO3, which can effectively inhibit the agglomeration of vanadium species in the process of impregnation. Furthermore, it can also increase the amount of oligomeric VOx, which can improve the denitration activity

Table1_Safety of subcutaneous immunotherapy with Novo-Helisen-Depot in the children: a retrospective analysis from a single center in Northern China.pdf

BackgroundLittle is known about the safety of mite extract product Novo-Helisen Depot (NHD) as subcutaneous immunotherapy (SCIT) in the children with mite allergy especially immediate/late local reaction (LRs).MethodsWe conducted a retrospective study analyzing the adverse events of the children undergoing subcutaneous immunotherapy with NHD. Adverse events included local and systemic adverse reactions (SRs) at the very early and late stage. The correlation of the basic characteristics, laboratory analysis results, LRs and SRs were analyzed.ResultsTwo hundred and eighty-seven patients received at least 15 months of subcutaneous immunotherapy with NHD were included in the analysis. Skin-prick testing (SPT) results of D. pteronyssinus was associated with an increased risk of immediate LRs in build-up phase (OR = 1.53, 95% CI: 1.02, 2.37) and delayed LRs in maintenance phase (OR = 1.58, 95% CI: 1.05, 2.46), while SPT results of D. farinae was associated with an increased risk of SRs (OR = 3.22, 95% CI: 1.17, 10.00) and severe SRs (OR = 7.68, 95% CI: 1.13, 109.50). Serum IgE level of D. pteronyssinus was associated with an increased risk of SRs (OR = 1.01, 95% CI: 1.00, 1.03). Patients with both asthma and allergic rhinitis was associated with an increased risk of SR, and severe SRs (P ConclusionNHD as SCIT is safe. The children with higher SPT level with D. farinae or D. pteronyssinus, higher serum IgE level of D. pteronyssinus, children with both asthma and allergic rhinitis, and the children with treatment interruption had higher risk of adverse events.</p

Data_Sheet_1_Cobalt Nanoparticles Encapsulated in Nitrogen-Doped Carbon Nanotube as Bifunctional-Catalyst for Rechargeable Zn-Air Batteries.PDF

Developing economic and efficient non-noble-metal electrocatalysts toward oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) is vitally important to improve the performance and economic outlook of alkaline-based rechargeable Zn-air battery technologies. In this work, a nitrogen-doped carbon nanotube encapsulated with metallic cobalt nanoparticles (Co@NC) was synthesized through a facile method and subsequent pyrolysis treatment. The field emission scanning electron microscope (FESEM), high resolution transmission electron microscopy (HRTEM), Raman spectra investigations demonstrate that the presence of Co induces the formation of carbon nanotube during the pyrolysis process and increase degree of graphitization of carbon nanotubes. The electrode activity is assessed by comparing OER with ORR indicators (ΔE). The ΔE value of Co@NC is 0.91 V, which is lower than the commercialized Pt/C (1.1 V) and nitrogen-doped carbon (NC) (1.17 V). The Co@NC-based primary Zn-air battery display an open circuit potential of 1.4 V, a high power density of 137 mW·cm−2, and outstanding energy density (708.3 mAh·kgZn-1 and 868.9 Wh kgZn-1 at 10 mA·cm−2), which batter than the commercialized Pt/C.</p

Additional file 1: of Neutrophil-lymphocyte ratio is associated with arterial stiffness in patients with peritoneal dialysis

Raw data of the study. (XLS 46 kb

Additional file 1 of Transcriptional regulation of metal metabolism- and nutrient absorption-related genes in Eucalyptus grandis by arbuscular mycorrhizal fungi at different zinc concentrations

Additional file 1: Table S1. General information of ZNT transporter genes identified in Eucalyptus grandis. Table S2. Pearson’s correlation analysis on ZNT family genes. Table S3. Pearson’s correlation analysis on COPT/Ctr family genes. Table S4. Pearson’s correlation analysis on YSL family genes. Table S5. Pearson’s correlation analysis on ZIFL family genes. Table S6. Pearson’s correlation analysis on HMA family genes. Table S7. Pearson’s correlation analysis on CE/MTP family genes. Table S8. Pearson’s correlation analysis on PHT family genes. Table S9. Pearson’s correlation analysis on AMT and NRT family genes. Table S10. Pearson’s correlation analysis on Potassium transporters family genes

Reviewer_2_v.1 – Supplemental material for Duration of treatment with inhaled corticosteroids in nonasthmatic eosinophilic bronchitis: a randomized open label trial

Supplemental material, Reviewer_2_v.1 for Duration of treatment with inhaled corticosteroids in nonasthmatic eosinophilic bronchitis: a randomized open label trial by Wenzhi Zhan, Jiaman Tang, Xiaomei Chen, Fang Yi, Lina Han, Baojuan Liu, Wei Luo, Qiaoli Chen and Kefang Lai in Therapeutic Advances in Respiratory Disease</p

Additional file 2 of Transcriptional regulation of metal metabolism- and nutrient absorption-related genes in Eucalyptus grandis by arbuscular mycorrhizal fungi at different zinc concentrations

Additional file 2

Additional file 4 of Transcriptional regulation of metal metabolism- and nutrient absorption-related genes in Eucalyptus grandis by arbuscular mycorrhizal fungi at different zinc concentrations

Additional file 4

DataSheet_1_The Combined Treatment With the FLT3-Inhibitor AC220 and the Complex I Inhibitor IACS-010759 Synergistically Depletes Wt- and FLT3-Mutated Acute Myeloid Leukemia Cells.zip

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy with a high mortality rate and relapse risk. Although progress on the genetic and molecular understanding of this disease has been made, the standard of care has changed minimally for the past 40 years and the five-year survival rate remains poor, warranting new treatment strategies. Here, we applied a two-step screening platform consisting of a primary cell viability screening and a secondary metabolomics-based phenotypic screening to find synergistic drug combinations to treat AML. A novel synergy between the oxidative phosphorylation inhibitor IACS-010759 and the FMS-like tyrosine kinase 3 (FLT3) inhibitor AC220 (quizartinib) was discovered in AML and then validated by ATP bioluminescence and apoptosis assays. In-depth stable isotope tracer metabolic flux analysis revealed that IACS-010759 and AC220 synergistically reduced glucose and glutamine enrichment in glycolysis and the TCA cycle, leading to impaired energy production and de novo nucleotide biosynthesis. In summary, we identified a novel drug combination, AC220 and IACS-010759, which synergistically inhibits cell growth in AML cells due to a major disruption of cell metabolism, regardless of FLT3 mutation status.</p

Association between Transforming Growth Factor-Beta 1 T869C Polymorphism and Ischemic Stroke: A Meta-Analysis

<div><p>Objective</p><p>To explore the association between transforming growth factor-beta1 (TGF-β1) T869C polymorphism and risk of ischemic stroke (IS) by performing a meta-analysis based on published articles.</p><p>Methods</p><p>Systematic electronic searches of PubMed, Science Direct, BIOSIS Previews, Chinese Biomedical Database, Chinese National Knowledge Infrastructure, and WANFANG Database were performed. The strength of the association was calculated by pooled odds ratios (ORs) with 95% confidence intervals (95%CIs). Subgroup analysis was conducted to explore potential sources of heterogeneity. Sensitivity analysis was performed to elucidate the stability of the outcomes. Publication bias was evaluated by Begg’s funnel plot and Egger’s test.</p><p>Results</p><p>A total of 6 studies involving 1701 cases were included. The overall estimates did not show any significant association between TGF-β1 T869C polymorphism and risk of IS under all genetic models (C vs. T: OR = 1.08,95%CI = 0.88–1.32; CC vs. TT:OR = 1.17,95%CI = 0.79–1.72; CT vs. TT: OR = 0.91, 95%CI = 0.68–1.22; CC+CT vs. TT: OR = 0.99, 95%CI = 0.73–1.35; CC vs. CT+TT: OR = 1.23, 95%CI = 0.95–1.59). Similar lacking associations were observed in subgroup analysis based on ethnicity and source of controls. When stratified by study design, significant increased association of IS risk was found in cohort studies under genetic models except recessive model(C vs. T: OR = 1.18, 95%CI = 1.05–1.32; CC vs. TT: OR = 1.40, 95%CI = 1.10–1.77; CT vs. TT: OR = 1.23, 95%CI = 1.02–1.49; CC+CT vs. TT: OR = 1.27, 95%CI = 1.03–1.57; CC vs. CT+TT, OR = 1.21, 95%CI = 0.99–1.47), whereas in case-control studies a significant decreased risk was detected under heterozygote comparison(CT vs. CC: OR = 0.72, 95%CI = 0.57–0.92). However, after correction for multiple testing, the associations were observed to be null significant in both cohort and case-control subgroups among all genetic models.</p><p>Conclusion</p><p>This meta-analysis suggested that current epidemiological studies of TGF-β1 T869C polymorphism are too inconsistent to draw a conclusion on the association with IS susceptibility. Given the small sample size and remarkable between-study heterogeneity, further well-designed prospective large-scale studies are warranted.</p></div