Computational Studies of Three-Dimensional Ocean Sound Fields in Areas of Complex Seafloor Topography and Active Ocean Dynamics

Time-evolving three-dimensional (four-dimensional) numerical modeling of sound is performed for ocean environmental conditions calculated using regional ocean flow models. The flow models solve the appropriate nonlinear equations in bands of resolved scales and frequencies. Subgrid scale processes are parameterized, as are boundary processes. The ocean fields are interpolated onto acoustic model grids that are two orders of magnitude tighter than the flow model grids. The computations provide reliable estimates of the acoustic effects of the resolved ocean processes such as geostrophic currents, mixed-layer changes, and internal tides, but they do not include the acoustic implications of unresolved structures such as nonlinear internal waves, sharp boundary layers, and small-scale intrusions. Examples of complicated sound fields from resolved and unresolved features will be presented, and prospects for applying the methods will be discussed

Issues and progress in the prediction of ocean submesoscale features and internal waves

Data-constrained dynamical ocean modeling for the purpose of detailed forecasting and prediction continues to evolve and improve in quality. Modeling methods and computational capabilities have each improved. The result is that mesoscale phenomena can be modeled with skill, given sufficient data. However, many submesoscale features are less well modeled and remain largely unpredicted from a deterministic event standpoint, and possibly also from a statistical property standpoint. A multi-institution project is underway with goals of uncovering more of the details of a few submesoscale processes, working toward better predictions of their occurrence and their variability. A further component of our project is application of the new ocean models to ocean acoustic modeling and prediction. This paper focuses on one portion of the ongoing work: Efforts to link nonhydrostatic-physics models of continental-shelf nonlinear internal wave evolution to data-driven regional models. Ocean front-related effects are also touched on.United States. Office of Naval Research (United States. Dept. of Defense. Multidisciplinary University Research Initiative (Ocean Acoustics Program Award N00014-11-1-0701))United States. Office of Naval Research (Grant N00014-12-1-0944)National Science Foundation (U.S.) (Grant OCE-1061160

Electrochemical determination of microRNAs based on isothermal strand-displacement polymerase reaction coupled with multienzyme functionalized magnetic micro-carriers

This study was supported by the National Natural Science Foundation of China (81371901), Doctoral Scientific Fund Project of the Ministry of Education of People's Republic of China (20134433110010), the Critical Point-of-Care Testing (CPOCT) Research grant of American Association for Clinical Chemistry (AACC) and 2015 Distinguished Academic Fellowships of Royal College of Engineering (DVF1415/2/79)

The Impact of Mobile Technology on English Writing Teaching: The Relationship between Interactive Feedback and Autonomous Learning Abilities

With the rapid development of information technology (IT), mobile technology has been widely applied in the field of education, particularly in language learning. English writing, as one of the core skills in language acquisition, faces numerous challenges within traditional teaching models, such as limited learner autonomy and the difficulty of meeting individualized needs. In recent years, mobile technology-assisted English writing teaching has become a new research focus, with interactive feedback mechanisms and the enhancement of autonomous learning abilities being identified as key factors influencing instructional effectiveness. This study aims to explore mobile network-based English writing teaching, specifically analyzing how locationaware features and interactive feedback can enhance students’ autonomous learning abilities. In particular, the study investigates the forms and challenges of mobile network-assisted English writing teaching, examining mobile network discovery technologies, similarity calculation, and evolutionary computation methods relevant to English writing teaching, and proposes strategies for enhancing autonomous learning through interactive feedback

Targeted drug delivery for the treatment of blood cancers

Blood cancers are a type of liquid tumor which means cancer is present in the body fluid. Multiple myeloma, leukemia, and lymphoma are the three common types of blood cancers. Chemotherapy is the major therapy of blood cancers by systemic administration of anticancer agents into the blood. However, a high incidence of relapse often happens, due to the low efficiency of the anticancer agents that accumulate in the tumor site, and therefore lead to a low survival rate of patients. This indicates an urgent need for a targeted drug delivery system to improve the safety and efficacy of therapeutics for blood cancers. In this review, we describe the current targeting strategies for blood cancers and recently investigated and approved drug delivery system formulations for blood cancers. In addition, we also discuss current challenges in the application of drug delivery systems for treating blood cancers

19th World Congress of Soil Science (WCSS 2010): Soil Solutions for a Changing World

A pot experiment was conducted to examine the effects of various fertilizers on the dynamics of soil-borne DDTs and their subsequent impacts on DDTs uptake by a test plant. The results show that there was a significantly lower soil residual DDTs concentration in the iron-rich fertilizer-treated soil than in other fertilizer-treated soils. However, all the non-iron-rich fertilizers showed no significant effect on the reduction of soil DDTs on the last day of the experiment, as compared to the control. There was a close relationship between the soil residual DDTs and plant tissue DDTs. This suggests that the uptake rate of DDTs by the plant was dependent on the concentration of soil-borne DDTs. Application of iron-rich fertilizer enhanced the degradation of the soil DDTs and subsequently reduced the uptake of DDTs by the test plant. The findings obtained from this study have implications for remediation of DDTs-polluted soil