Novel g‑C₃N₄/C/Fe₂O₃ Composite for Efficient Photocatalytic Reduction of Aqueous Cr(VI) under Light Irradiation

Research on the rational design of photocatalysts for efficient hexavalent chromium (Cr­(VI)) reduction from Cr­(VI)-containing wastewater has attracted widespread attention. In this paper, a novel g-C3N4/C/Fe2O3 photocatalyst was successfully synthesized by anchoring g-C3N4 nanosheets onto C/Fe2O3 that was prepared using collagen fiber as the biochar resource following the Fe tanning mechanism to reduce Cr­(VI) under artificial solar irradiation. Under the same conditions, the as-prepared g-C3N4/C/Fe2O3 photocatalyst exhibited higher Cr­(VI) reduction efficiency than g-C3N4, and the Cr­(VI) reduction efficiency increased as Fe content in the g-C3N4/C/Fe2O3 photocatalyst increased. The enhanced photocatalytic performance was primarily ascribed to the formation of an indirect Z-scheme heterojunction between C/Fe2O3 and g-C3N4, which improved the separation efficiency of the photogenerated charge carrier. Furthermore, radical trapping indicated that photoinduced electrons (e–) were the main factor for Cr­(VI) reduction. This work provides guidance for high value-added utilization of collagen fiber in constructing efficient light-driven photocatalysts and practical Cr­(VI) removal from wastewater

Development of Kilogram-Scale Synthesis of EGFR Inhibitor EAI045

Herein, we report a synthetic route for an EGFR inhibitor, 2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl) acetic acid (EAI045), using a three-step approach. This short and efficient route is the first report of a scalable process for EAI045, which employs a convergent three-component coupling strategy as the key step, producing EAI045 in good yield on kilogram scale

The differences in clinical characteristics and plasma catestatin levels between normal group and CTO group.

<p>The differences in clinical characteristics and plasma catestatin levels between normal group and CTO group.</p

The differences between good collateral group and poor collateral group among CTO patients.

<p>The differences between good collateral group and poor collateral group among CTO patients.</p

The relationship between plasma catestatin levels and Rentrop scores.

<p>The catestatin levels in the different Rentrop score groups were respectively 1.47±1.29 ng/ml (grade0, n = 12); 1.83±0.82 ng/ml (grade1, n = 8); 2.31±0.77 ng/ml (grade2, n = 14); and 2.54±0.61 ng/ml (grade3, n = 4). The differences was significant between grade0 group and grade2 group (p = 0.034).</p

Ultrafast Proteinquake Dynamics in Cytochrome <i>c</i>

We report here our systematic studies of the heme dynamics and induced protein conformational relaxations in two redox states of ferric and ferrous cytochrome c upon femtosecond excitation. With a wide range of probing wavelengths from the visible to the UV and a site-directed mutation we unambiguously determined that the protein dynamics in the two states are drastically different. For the ferrous state the heme transforms from 6-fold to 5-fold coordination with ultrafast ligand dissociation in less than 100 fs, followed by vibrational cooling within several picoseconds, but then recombining back to its original 6-fold coordination in 7 ps. Such impulsive bond breaking and late rebinding generate proteinquakes and strongly perturb the local heme site and shake global protein conformation, which were found to completely recover in 13 and 42 ps, respectively. For the ferric state the heme however maintains its 6-fold coordination. The dynamics mainly occur at the local site, including ultrafast internal conversion in hundreds of femtoseconds, vibrational cooling on the similar picosecond time scale, and complete ground-state recovery in 10 ps, and no global conformation relaxation was observed

Charge Recombination versus Charge Separation in Donor−Bridge−Acceptor Systems

Optimizing the ratio of the rates for charge separation (CS) over charge recombination (CR) is crucial to create long-lived charge-separated states. Mastering the factors that govern the electron transfer (ET) rates is essential when trying to achieve molecular-scale electronics, artificial photosynthesis, and also for the further development of solar cells. Much work has been put into the question of how the donor−acceptor distances and donor−bridge energy gaps affect the electronic coupling, VDA, and thus the rates of ET. We present here a unique comparison on how these factors differently influence the rates for CS and CR in a porphyrin-based donor−bridge−acceptor model system. Our system contains three series, each of which focuses on a separate charge-transfer rate-determining factor, the donor−acceptor distance, the donor−bridge energy gap, and last, the influence of the electron acceptor on the rate for charge transfer. In these three series both CS and CR are governed by superexchange interactions which make a CR/CS comparative study ideal. We show here that the exponential distance dependence increases slightly for CR compared to that for CS as a result of the increased tunneling barrier height for this reaction, in accordance with the McConnell superexchange model. We also show that the dependence on the tunneling barrier height is different for CS and CR. This difference is highly dependent on the electron acceptor and thus cannot solely be explained by the differences in the frontier orbitals of the electron donor in these porphyrin systems

The flowchart of the study subjects.

<p>The 640 patients with chest pain for suspicious CAD who underwent coronary angiography or percutaneous coronary intervention (PCI) were screened in series. According to the results of angiography, 518 patients had coronary stenosis (not CTO), 41 patients had normal coronary angigraphy, 81 patients had coronary total occlusion lesions. There were 3 patients with normal coronary angiography and 43 patients with coronary total occlusion were excluded. Finally, there were 38 patients in normal group and 38 patients in CTO group, respectively.</p

The associations between plasma catestatin and coronary collateral development by multiple linear regression.

<p>The associations between plasma catestatin and coronary collateral development by multiple linear regression.</p

Comparisons on overall satisfaction of community health service centers residents in urban and suburban areas of Shanghai from 2009 to 2014.

<p>Comparisons on overall satisfaction of community health service centers residents in urban and suburban areas of Shanghai from 2009 to 2014.</p