Versatile Pyrrole Synthesis through Ruthenium(II)-Catalyzed Alkene C–H Bond Functionalization on Enamines

An efficient ruthenium(II) catalyst enabled broadly applicable oxidative alkyne annulations with electron-rich enamines to provide diversely decorated pyrroles, even in an aerobic fashion with air as the ideal oxidant

Rhodium(III)-Catalyzed C–H Activation/Alkyne Annulation by Weak Coordination of Peresters with O–O Bond as an Internal Oxidant

A redox-economic strategy has been developed, involved in an efficient Rh­(III)-catalyzed oxidative C–H activation and alkyne annulation with perester as the oxidizing directing group. In this process, the cleavage of an oxidizing O–O bond as an internal oxidant is described for the first time. This reaction could be carried out under mild conditions and exhibits excellent regioselectivity and wide functional groups tolerance

Rh(III)-Catalyzed One-Pot Synthesis of Benzimidazoquinazolines via C–H Amidation–Cyclization of <i>N</i>‑LG-2-phenylbenzoimidazoles

An efficient protocol to synthesize substituted benzo­[4,5]­imidazo­[1,2-c]­quinazolines starting from N-LG-2-phenylbenzoimidazole and dioxazolones catalyzed by Rh­(III) or Ir­(III) has been developed. Various substituted benzo­[4,5]­imidazo­[1,2-c]­quinazolines could be easily provided in up to 99% yield. A large range of substrates and functional groups are compatible for this transformation. This method features low catalyst loading, acid-free conditions, and low solvent consumption

Ruthenium-Catalyzed Oxidative C–H Alkenylations of Anilides and Benzamides in Water

A cationic ruthenium(II) complex enabled efficient oxidative alkenylations of anilides in water as a green solvent and proved applicable to double C–H bond functionalizations of (hetero)aromatic amides with ample scope. Detailed studies provided strong support for a change of ruthenation mechanism in the two transformations, with an irreversible metalation as the key step in cross-dehydrogenative alkenylations of benzamides

Supplementary document for Deep learning enabled inverse design of bound states in the continuum with ultrahigh Q factor - 6819090.pdf

additional information on network and suggested experimental procedure

Ruthenium(II)-Catalyzed C(sp³)–H α‑Alkylation of Pyrrolidines

A catalytic system comprising [RuCl₂(PPh₃)₃], AgOTf, and BINAP enabled atom- and step-economical additions of C­(sp³)–H bonds onto unactivated alkenes <b>2</b> under comparably mild reaction conditions. The pyridyl directing group was easily removed to furnish the corresponding (<i>NH</i>)-free amines with ample scope

Supplementary document for Multi-mode resonance of bound states in the continuum in dielectric metasurfaces - 6894313.pdf

Reflection for silicon bar with different structural parameters, and the loss and feasibility of the experimen

Copper-Catalyzed Synthesis of 2‑Arylquinazolinones from 2‑Arylindoles with Amines or Ammoniums

A novel copper-catalyzed synthesis of quinazolinones from easily available 2-arylindoles and amines or ammoniums has been developed, which provided various quinazolinones in up to 99% yields for 43 examples. This strategy features tolerance of a wide range of functional groups, easily available starting materials, simple operation, mild reaction conditions, and environmental friendliness

DNA Origami-Enabled Gene Localization of Repetitive Sequences

Repetitive sequences, which make up over 50% of human DNA, have diverse applications in disease diagnosis, forensic identification, paternity testing, and population genetic analysis due to their crucial functions for gene regulation. However, representative detection technologies such as sequencing and fluorescence imaging suffer from time-consuming protocols, high cost, and inaccuracy of the position and order of repetitive sequences. Here, we develop a precise and cost-effective strategy that combines the high resolution of atomic force microscopy with the shape customizability of DNA origami for repetitive sequence-specific gene localization. “Tri-block” DNA structures were specifically designed to connect repetitive sequences to DNA origami tags, thereby revealing precise genetic information in terms of position and sequence for high-resolution and high-precision visualization of repetitive sequences. More importantly, we achieved the results of simultaneous detection of different DNA repetitive sequences on the gene template with a resolution of ∼6.5 nm (19 nt). This strategy is characterized by high efficiency, high precision, low operational complexity, and low labor/time costs, providing a powerful complement to sequencing technologies for gene localization of repetitive sequences

First-Principles Study of Rectification in Bis-2-(5-ethynylthienyl)ethyne Molecular Junctions

Using density functional theory (DFT) combined with the first-principles nonequilibrium Green’s function (NEGF), we investigated the electron-transport properties and rectifying behaviors of several molecular junctions based on the bis-2-(5-ethynylthienyl)ethyne (BETE) molecule. To examine the roles of different rectification factors, asymmetric electrode–molecule contacts and donor–acceptor substituent groups were introduced into the BETE-based molecular junction. The asymmetric current–voltage characteristics were obtained for the molecular junctions containing asymmetric contacts and donor–acceptor groups. In our models, the computed rectification ratios show that the mode of electrode–molecule contacts plays a crucial role in rectification and that the rectifying effect is not enhanced significantly by introducing the additional donor–acceptor components for the molecular rectifier with asymmetric electrode–molecule contacts. The current–voltage characteristics and rectifying behaviors are discussed in terms of transmission spectra, molecular projected self-consistent Hamiltonian (MPSH) states, and energy levels of MPSH states