Scatterplot showing the distribution size of gamma zone versus length of the peripapillary scleral flange (locally weighted scatterplot smoothing (LOESS) statistics).

<p>Scatterplot showing the distribution size of gamma zone versus length of the peripapillary scleral flange (locally weighted scatterplot smoothing (LOESS) statistics).</p

Photomicrograph of the optic nerve head (staining: PAS); arrows #1 and #2: pia mater of the optic nerve; arrows #3 and #4: peripapillary scleral flange as roof of the orbital cerebrospinal fluid space; black stars: dura mater of the optic nerve.

<p>Photomicrograph of the optic nerve head (staining: PAS); arrows #1 and #2: pia mater of the optic nerve; arrows #3 and #4: peripapillary scleral flange as roof of the orbital cerebrospinal fluid space; black stars: dura mater of the optic nerve.</p

Photomicrograph of the optic nerve head (staining: PAS); arrows #1 and #2: pia mater of the optic nerve; arrow #3: end of Bruch's membrane; arrow #4: projection of the outer margin of the pia mater of the optic nerve; Gamma zone: region between arrows #3 and #4; black star: beginning of dura mater of the optic nerve.

<p>Photomicrograph of the optic nerve head (staining: PAS); arrows #1 and #2: pia mater of the optic nerve; arrow #3: end of Bruch's membrane; arrow #4: projection of the outer margin of the pia mater of the optic nerve; Gamma zone: region between arrows #3 and #4; black star: beginning of dura mater of the optic nerve.</p

Scatterplot showing the distribution size of gamma zone versus thickness of the peripapillary scleral flange (locally weighted scatterplot smoothing (LOESS) statistics).

<p>Scatterplot showing the distribution size of gamma zone versus thickness of the peripapillary scleral flange (locally weighted scatterplot smoothing (LOESS) statistics).</p

Photomicrograph of a highly myopic optic nerve head (staining: PAS); black stars: inner border of the optic nerve; arrows #1: pia mater of the optic nerve; arrows #2: peripapillary scleral flange as roof of the widened orbital cerebrospinal fluid space; arrows #3: dura mater of the optic nerve; arrow #4: arterial circle of Zinn-Haller; A–B: Pia mater (potentially the “peripapillary scleral ring” upon ophthalmoscopy); B–C: Delta zone (no blood vessels >50 µm diameter within gamma zone); C–D: remaining Gamma zone (peripapillary sclera without overlying choroid, Bruch's membrane and deep retinal layers).

<p>Photomicrograph of a highly myopic optic nerve head (staining: PAS); black stars: inner border of the optic nerve; arrows #1: pia mater of the optic nerve; arrows #2: peripapillary scleral flange as roof of the widened orbital cerebrospinal fluid space; arrows #3: dura mater of the optic nerve; arrow #4: arterial circle of Zinn-Haller; A–B: Pia mater (potentially the “peripapillary scleral ring” upon ophthalmoscopy); B–C: Delta zone (no blood vessels >50 µm diameter within gamma zone); C–D: remaining Gamma zone (peripapillary sclera without overlying choroid, Bruch's membrane and deep retinal layers).</p

Photomicrograph of a glaucomatous optic nerve head (staining: PAS).

<p>Left: arrow #1 end of Bruch's membrane; arrow #2: beginning of choriocapillaris not occluded beneath Bruch's membrane; arrow #3: beginning retinal photoreceptors on Bruch's membrane; arrow #4: beginning of retinal pigment epithelium cells on Bruch's membrane. Right: higher magnification of beta zone; Black arrow: End of Bruch's membrane at the optic disc border; White arrow: open choriocapillaris; Red arrow: end of photoreceptor layer, choriocapillaris open.</p

Scatterplot showing the distribution size of gamma zone versus axial length (locally weighted scatterplot smoothing (LOESS) statistics).

<p>Scatterplot showing the distribution size of gamma zone versus axial length (locally weighted scatterplot smoothing (LOESS) statistics).</p