80 research outputs found

    Treatment of obese patients with binge eating disorder using topiramate: a review

    Get PDF
    Topiramate is an anticonvulsant drug used for the treatment of epilepsy and prophylaxis of migraine. Some authors have proposed its use as a mood stabilizer and have reported its efficacy in reducing impulsiveness and improving mood regulation, possibly via its antagonism to glutamatergic transmission in the lateral hypothalamus, although this indication is still controversial. Weight loss is a side effect consistently reported in the medical literature in patients treated with topiramate. Given its potential role in stabilizing mood and reducing impulse control problems and weight, topiramate has been proposed as a treatment for obese patients with binge eating disorder (BED). The aim of this paper is to review published data on the efficacy and safety of topiramate for the treatment of obese subjects with BED. Although the evidence is preliminary, topiramate appears to be a relatively safe and effective treatment for obese subjects with BED. Limitations of the studies and future directions for research are discussed

    Harm Avoidance and Self-Directedness Characterize Fibromyalgic Patients and the Symptom Severity

    Get PDF
    AbstractObjective: Evidence in the literature suggests peculiar personality traits for fibromyalgic patients, and it has been suggested that personality characteristics may be involved in patients' different symptomatic events and responses to treatment. The aim of the study is to investigate the personality characteristics of Italian FM patients and to explore the possibility of clustering them considering both personality traits and clinical characteristics.Design: The study used a cross-sectional methodology and involved a control group. A self-assessment procedure was used for data gathering. The study included 87 female FM patients and 83 healthy females. Patients were approached and interviewed in person during a psychiatric consultation. Healthy people were recruited from general practices with previous telephone contact.Main Outcome Measures: Participants responded to the Hospital Anxiety and Depression Scale (HADS), the Temperament and Character Inventory (TCI), the Fibromyalgia Impact Questionnaire (FIQ) and the Short-Form-36 Health Survey (SF-36).Results: FM patients scored significantly different from healthy participants on the Harm-Avoidance (HA), Novelty Seeking (NS) and Self-Directedness (SD). Two clusters were identified: patients in Cluster 1 (n=37) had higher scores on HA and lower scores on RD, SD and Cooperativeness and reported more serious fibromyalgia and more severe anxious-depressive symptomatology than did patients in Cluster 2 (n=46).Conclusion: This study confirms the presence of certain personality traits in the FM population. In particular, high levels of Harm Avoidance and low levels of Self-Directedness characterize a subgroup of FM patients with more severe anxious-depressive symptomatology. According to these findings, personality assessment could be useful in the diagnostic process to tailor therapeutic interventions to the personality characteristics

    The Impact of COVID-19 on Mental Health in Medical Students: A Cross-Sectional Survey Study in Italy

    Get PDF
    Background: This study aimed to assess the impact of the COVID-19 pandemic in terms of the prevalence of anxiety, depression and stress symptoms in Italian medical students and to identify the associated factors. Design and Methods: A cross-sectional online survey was administered to second-sixth year medical students of the University of Torino, collecting data on the students’ sociodemographics, COVID-19 exposure, anxiety, depression and stress symptoms. Three hierarchical regressions adjusted for age, gender and year of study were executed. Results: The sample size was 1359. The prevalence of anxiety, depression symptoms, moderate perceived stress and severe perceived stress was 47.8%, 52.1%, 56.2% and 28.4%, respectively. The factors associated with mental health symptoms were: being a woman, a family history of psychiatric disorders, living off-site, competitive/hostile climates and unsatisfying friendships among classmates, poor relationships with cohabitants, negative judgment of medical school choice, fear of COVID-19 infection, feelings of loneliness, distressing existential reflections, and a worsening psychological condition related to the pandemic. Being in the fourth or sixth year constituted a protective factor for depression symptoms. Conclusions: Mental health in medical students was associated with both COVID-independent and COVID-related factors. Accessibility to effective interventions must be increased to counteract these changes

    The Consequences of the Pandemic on Medical Students' Depressive Symptoms and Perceived Stress: A Repeated Cross-Sectional Survey with a Nested Longitudinal Subsample

    Get PDF
    This study aimed to explore the impact of the pandemic on medical students’ mental health in Italy using a repeated cross-sectional survey with a nested longitudinal subsample (first timepoint: 2018; second: 2020/2021). Three research questions (RQs) were investigated. Study 1 (longitudinal sub-sample) explored whether medical students had higher levels of depressive symptoms and stress during the pandemic compared with a pre-pandemic period (RQ1) and what variables were associated with these conditions during the pandemic adjusting for baseline levels (RQ2). Study 2 (repeated cross-sectional data) aimed to examine whether medical students had higher levels of these conditions during the pandemic compared with their same-year peers during a pre-pandemic period (RQ3). In Study 1, higher levels of depressive symptoms and stress were shown during the pandemic (RQ1). Multivariable models highlighted associations between poor mental health and worsening of the judgment of medical school choice, worsened psychological condition due to the pandemic, economic repercussions due to the pandemic, and baseline levels of symptoms (RQ2). In Study 2, our findings reported higher levels of depressive symptoms and stress during the pandemic, also adjusting for other variables (RQ3). In conclusion, depressive symptoms and stress were greater during the pandemic. The most relevant variables were pandemic-related items and medical school choice judgment

    La salute mentale negli studenti di medicina: il progetto del Servizio di Aiuto Psicologico (SAP) dell’Università degli Studi di Torino

    Get PDF
         Dalla letteratura emerge come gli studenti di medicina spesso presentino livelli di ansia, stress e de-pressione superiori alla popolazione generale. Si rende quindi sempre più necessario un supporto psi-cologico gratuito e fruibile interno alle università. La facoltà di Medicina e Chirurgia dell’Università de-gli Studi di Torino può vantare un servizio di aiuto psicologico (SAP) dedicato. Il presente studio ha lo scopo di illustrare in termini sociodemografici, clinici e psicopatologici la coorte di studenti che ha usufruito del servizio. Il progetto prevede un colloquio conoscitivo al termine del quale, se necessario, seguirà una presa in carico dal punto di vista psicologico e/o psichiatrico; agli studenti inoltre viene chiesto di compilare alcuni test psicometrici per valutare depressione, ansia e stress. Da gennaio 2019 ad agosto 2020, 166 studenti hanno fatto richiesta per un primo colloquio. Dal nostro studio emerge come, in linea con la letteratura, una sintomatologia depressiva e/o di tipo ansioso sia presen-te negli utenti. I dati raccolti e altresì il feedback ricevuto dagli studenti dimostrano l’utilità del servi-zio.      Dalla letteratura emerge come gli studenti di medicina spesso presentino livelli di ansia, stress e de-pressione superiori alla popolazione generale. Si rende quindi sempre più necessario un supporto psi-cologico gratuito e fruibile interno alle università. La facoltà di Medicina e Chirurgia dell’Università de-gli Studi di Torino può vantare un servizio di aiuto psicologico (SAP) dedicato. Il presente studio ha lo scopo di illustrare in termini sociodemografici, clinici e psicopatologici la coorte di studenti che ha usufruito del servizio. Il progetto prevede un colloquio conoscitivo al termine del quale, se necessario, seguirà una presa in carico dal punto di vista psicologico e/o psichiatrico; agli studenti inoltre viene chiesto di compilare alcuni test psicometrici per valutare depressione, ansia e stress. Da gennaio 2019 ad agosto 2020, 166 studenti hanno fatto richiesta per un primo colloquio. Dal nostro studio emerge come, in linea con la letteratura, una sintomatologia depressiva e/o di tipo ansioso sia presen-te negli utenti. I dati raccolti e altresì il feedback ricevuto dagli studenti dimostrano l’utilità del servi-zio.&nbsp

    Alexithymia in Fibromyalgia Syndrome: is it a discriminant factor?

    Get PDF
    9nonemixedGHIGGIA, ADA; TESIO, VALENTINA; ROMEO, ANNUNZIATA; Monoli, F; COLONNA, FABRIZIO; LEOMBRUNI, Paolo; Fusaro, E; TORTA, Riccardo; CASTELLI, LorysGhiggia, Ada; Tesio, Valentina; Romeo, Annunziata; Monoli, F; Colonna, Fabrizio; Leombruni, Paolo; Fusaro, E; Torta, Riccardo; Castelli, Lory

    Alexithymia, anger and psychological distress in patients with myofascial pain: a case-control study

    Get PDF
    Aims: The aim of this study was to investigate psychological distress, anger and alexithymia in a group of patients affected by myofascial pain (MP) in the facial region. Methods: 45 MP patients [mean (SD) age: 38.9 (11.6)] and 45 female healthy controls [mean (SD) age: 37.8 (13.7)] were assessed medically and psychologically. The medically evaluation consisted of muscle palpation of the pericranial and cervical muscles. The psychological evaluation included the assessment of depression (Beck Depression Inventory—short form), anxiety [State-Trait Anxiety Inventory Form Y (STAI-Y)], emotional distress [Distress Thermometer (DT)], anger [State-Trait Anger Expression Inventory—2 (STAXI-2)], and alexithymia [Toronto Alexithymia Scale (TAS)]. Results: the MP patients showed significantly higher scores in the depression, anxiety and emotional distress inventories. With regard to anger, only the Anger Expression-In scale showed a significant difference between the groups, with higher scores for the MP patients. In addition, the MP patients showed significantly higher alexithymic scores, in particular in the Difficulty in identifying feelings (F1) subscale of the TAS-20. Alexithymia was positively correlated with the Anger Expression-In scale. Both anger and alexithymia showed significant positive correlations with anxiety scores, but only anger was positively correlated with depression. Conclusion: A higher prevalence of depressive and anxiety symptoms associated with a higher prevalence of alexithymia and expression-in modality to cope with anger was found in the MP patients. Because the presence of such psychological aspects could contribute to generate or exacerbate the suffering of these patients, our results highlight the need to include accurate investigation of psychological aspects in MP patients in normal clinical practice in order to allow clinicians to carry out more efficacious management and treatment strategies
    • …
    corecore