729 research outputs found
Blogging: self presentation and privacy
Blogs are permeating most niches of social life, and addressing a wide range of topics from scholarly and political issues1 to family and children’s daily lives. By their very nature, blogs raise a number of privacy issues as they are easy to produce and disseminate, resulting in large amounts of sometimes personal information being broadcast across the Internet in a persistent and cumulative manner. This article reports the preliminary findings of an online survey of bloggers from around the world. The survey explored bloggers’ subjective sense of privacy by examining their blogging practices and their expectations of privacy when publishing online. The findings suggest that blogging offers individuals a unique opportunity to work on their self-identity via the degree of self-expression and social interaction that is available in this medium. This finding helps to explain why bloggers consciously bring the ‘private’ to the public realm, despite the inherent privacy risks they face in doing so
Labeless and reversible immunosensor assay based upon an electrochemical current-transient protocol
A novel labeless and reversible immunoassay based upon an electrochemical
current-transient protocol is reported which offers many advantages in
comparison to classical immuno-biochemical analyses in terms of simplicity,
speed of response, reusability and possibility of multiple determinations.
Conducting polypyrrole films containing antibodies against 1) Bovine Serum
Albumin (BSA) and 2) Digoxin were deposited on the surface of platinum
electrodes to produce conductive affinity matrices having clearly defined
binding characteristics. The deposition process has been investigated using 125I
labelled anti-digoxin to determine optimal fabrication protocols. Antibody
integrity and activity, together with non-specific binding of antigen on the
conducting matrix have also been investigated using tritiated digoxin to probe
polypyrrole/anti-digoxin films. Amperometric responses to digoxin were recorded
in flow conditions using these films, but the technique was limited in use
mainly due to baseline instability. Anti-BSA - polypyrrole matrices were
investigated in more detail in both flow and quiescent conditions. No observable
response was found in flow conditions, however under quiescent conditions (in
non-stirred batch cell), anti-BSA – polypyrrole films have been demonstrated to
function as novel quantitative chronoamperometric immuno-biosensors when
interrogated using a pulsed potential waveform. The behaviour of the electrodes
showed that the antibody/antigen binding and/or interaction process underlying
the response observed was reversible in nature, indicating that the electrodes
could be used for multiple sensing protocols. Calibration profiles for BSA
demonstrated linearity for a concentration range of 0-50 ppm but tended towards
a plateau at higher concentrations. Factors relating to replicate sensor
production, sample measurement and reproducibility are discuss
Sagittal Subtalar and Talocrural Joint Assessment During Ambulation With Controlled Ankle Movement (CAM) Boots
Background: The purpose of the current study was to determine sagittal plane talocrural and subtalar kinematic differences between barefoot and controlled ankle movement (CAM) boot walking. This study used fluoroscopic images to determine talar motion relative to tibia and calcaneal motion relative to talus.
Methods: Fourteen male subjects (mean age 24.1 ± 3.5 years) screened for normal gait were tested. A fluoroscopy unit was used to collect images at 200 Hz during stance. Sagittal motion of the talocrural and subtalar joints were analyzed barefoot and within short and tall CAM boots.
Results: Barefoot talocrural mean maximum plantar and dorsiflexion were 9.2 ± 5.4 degrees and −7.5 ± 7.4 degrees, respectively; short CAM boot mean maximum plantar and dorsiflexion were 3.2 ± 4.0 degrees and −4.8 ± 10.2 degrees, respectively; and tall CAM boot mean maximum plantar and dorsiflexion were −0.2 ± 3.5 degrees and −2.4 ± 5.1 degrees, respectively. Talocrural mean range of motion (ROM) decreased from barefoot (16.7 ± 5.1 degrees) to short CAM boot (8.0 ± 4.9 degrees) to tall CAM boot (2.2 ± 2.5 degrees). Subtalar mean maximum plantarflexion angles were 5.3 ± 5.6 degrees for barefoot walking, 4.1 ± 5.9 degrees for short CAM boot walking, and 3.0 ± 4.7 degrees for tall CAM boot walking. Mean minimum subtalar plantarflexion angles were 0.7 ± 3.2 degrees for barefoot walking, 0.7 ± 2.9 degrees for short CAM boot walking, and 0.1 ± 4.8 degrees for tall CAM boot walking. Subtalar mean ROM decreased from barefoot (4.6 ± 3.9 degrees) to short CAM boot (3.4 ± 3.8 degrees) to tall CAM boot (2.9 ± 2.6 degrees).
Conclusion: Tall and short CAM boot intervention was shown to limit both talocrural and subtalar motion in the sagittal plane during ambulation. The greatest reductions were seen with the tall CAM boot, which limited talocrural motion by 86.8% and subtalar motion by 37.0% compared to barefoot. Short CAM boot intervention reduced talocrural motion by 52.1% and subtalar motion by 26.1% compared to barefoot.
Clinical Relevance: Both short and tall CAM boots reduced talocrural and subtalar motion during gait. The short CAM boot was more convenient to use, whereas the tall CAM boot more effectively reduced motion. In treatments requiring greater immobilization of the talocrural and subtalar joints, the tall CAM boot should be considered
The Robo-AO-2 facility for rapid visible/near-infrared AO imaging and the demonstration of hybrid techniques
We are building a next-generation laser adaptive optics system, Robo-AO-2,
for the UH 2.2-m telescope that will deliver robotic, diffraction-limited
observations at visible and near-infrared wavelengths in unprecedented numbers.
The superior Maunakea observing site, expanded spectral range and rapid
response to high-priority events represent a significant advance over the
prototype. Robo-AO-2 will include a new reconfigurable natural guide star
sensor for exquisite wavefront correction on bright targets and the
demonstration of potentially transformative hybrid AO techniques that promise
to extend the faintness limit on current and future exoplanet adaptive optics
systems.Comment: 15 page
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The LONI QC System: A Semi-Automated, Web-Based and Freely-Available Environment for the Comprehensive Quality Control of Neuroimaging Data.
Quantifying, controlling, and monitoring image quality is an essential prerequisite for ensuring the validity and reproducibility of many types of neuroimaging data analyses. Implementation of quality control (QC) procedures is the key to ensuring that neuroimaging data are of high-quality and their validity in the subsequent analyses. We introduce the QC system of the Laboratory of Neuro Imaging (LONI): a web-based system featuring a workflow for the assessment of various modality and contrast brain imaging data. The design allows users to anonymously upload imaging data to the LONI-QC system. It then computes an exhaustive set of QC metrics which aids users to perform a standardized QC by generating a range of scalar and vector statistics. These procedures are performed in parallel using a large compute cluster. Finally, the system offers an automated QC procedure for structural MRI, which can flag each QC metric as being 'good' or 'bad.' Validation using various sets of data acquired from a single scanner and from multiple sites demonstrated the reproducibility of our QC metrics, and the sensitivity and specificity of the proposed Auto QC to 'bad' quality images in comparison to visual inspection. To the best of our knowledge, LONI-QC is the first online QC system that uniquely supports the variety of functionality where we compute numerous QC metrics and perform visual/automated image QC of multi-contrast and multi-modal brain imaging data. The LONI-QC system has been used to assess the quality of large neuroimaging datasets acquired as part of various multi-site studies such as the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Study and the Alzheimer's Disease Neuroimaging Initiative (ADNI). LONI-QC's functionality is freely available to users worldwide and its adoption by imaging researchers is likely to contribute substantially to upholding high standards of brain image data quality and to implementing these standards across the neuroimaging community
KELT-8b: A highly inflated transiting hot Jupiter and a new technique for extracting high-precision radial velocities from noisy spectra
We announce the discovery of a highly inflated transiting hot Jupiter
discovered by the KELT-North survey. A global analysis including constraints
from isochrones indicates that the V = 10.8 host star (HD 343246) is a mildly
evolved, G dwarf with K, , , an inferred mass
M, and radius
R. The planetary companion has mass , radius
, surface gravity , and density
g cm. The planet is on a roughly
circular orbit with semimajor axis AU and
eccentricity . The best-fit linear ephemeris is
BJD and
days. This planet is one of the most inflated of all known transiting
exoplanets, making it one of the few members of a class of extremely low
density, highly-irradiated gas giants. The low stellar and large
implied radius are supported by stellar density constraints from follow-up
light curves, plus an evolutionary and space motion analysis. We also develop a
new technique to extract high precision radial velocities from noisy spectra
that reduces the observing time needed to confirm transiting planet candidates.
This planet boasts deep transits of a bright star, a large inferred atmospheric
scale height, and a high equilibrium temperature of
K, assuming zero albedo and perfect heat redistribution, making it one of the
best targets for future atmospheric characterization studies.Comment: Submitted to ApJ, feedback is welcom
Notions of agency in early literacy classrooms: assemblages and productive intersections
Agency and its role in the early literacy classroom has long been a topic for debate. While sociocultural accounts often portray the child as a cultural agent who negotiates their own participation in classroom culture and literacy learning, more recent framings draw attention from the individual subject, instead seeing agency as dispersed across people and materials. In this article I draw on my experiences of following children as they followed their interests in an early literacy classroom, drawing on the concepts of assemblage and people yet to come, as defined by Deleuze and Guattari and Spinoza’s common notion. I provide one illustrative account of moment-by-moment activity and suggest that in education settings it is useful to see activity as a direct and ongoing interplay of three dimensions: children’s moving bodies; the classroom; and its materials. I propose that children’s ongoing movements create possibilities for ‘doing’ and ‘being’ that flow across and between children. I argue that thinking with assemblage can draw attention to both the potentiality and the power dynamics inherent in the ongoing present and also counter preconceived notions of individual child agency and linear trajectories of literacy development, and the inequalities this these concepts can perpetuate within early education settings
SDSS-IV MaNGA: faint quenched galaxies I- sample selection and evidence for environmental quenching
SJP acknowledges postdoctoral funding from the University of Portsmouth. AW acknowledges support of a Leverhulme Early Career Fellowship. This work was supported by World Premier International Research Center Initiative (WPI Initiative), MEXT, Japan. J. F-B. acknowledges support from grant AYA2013-48226-C3-1-P from the Spanish Ministry of Economy and Competitiveness (MINECO), as well as from the FP7 Marie Curie Actions of the European Commission, via the Initial Training Network DAGAL under REA grant agreement number 289313. MAB acknowledges support from NSF AST 1517006.Using kinematic maps from the Sloan Digital Sky Survey (SDSS) Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey, we reveal that the majority of low-mass quenched galaxies exhibit coherent rotation in their stellar kinematics. Our sample includes all 39 quenched low-mass galaxies observed in the first year of MaNGA. The galaxies are selected with Mr > -19.1, stellar masses109 M⊙ 1.9. They lie on the size-magnitude and σ-luminosity relations for previously studied dwarf galaxies. Just six (15 ± 5.7 per cent) are found to have rotation speeds ve, rot 5 × 1010 M⊙), supporting the hypothesis that galaxy-galaxy or galaxy-group interactions quench star formation in low-mass galaxies. The local bright galaxy density for our sample is ρproj = 8.2 ± 2.0 Mpc-2, compared to ρproj = 2.1 ± 0.4 Mpc-2 for a star forming comparison sample,confirming that the quenched low mass galaxies are preferentially found in higher density environments.PostprintPeer reviewe
The use of routine outcome measures in two child and adolescent mental health services: a completed audit cycle
Background: Routine outcome measurement (ROM) is important for assessing the clinical effectiveness of health services and for monitoring patient outcomes. Within Child and Adolescent Mental Health Services (CAMHS) in the UK the adoption of ROM in CAMHS has been supported by both national and local initiatives (such as government strategies, local commissioning policy, and research). Methods: With the aim of assessing how these policies and initiatives may have influenced the uptake of ROM within two different CAMHS we report the findings of two case-note audits: a baseline audit conducted in January 2011 and a re-audit conducted two years later in December 2012-February 2013. Results: The findings show an increase in both the single and repeated use of outcome measures from the time of the original audit, with repeated use (baseline and follow-up) of the Health of the Nation Outcome Scale for Children and Adolescents (HoNOSCA) scale increasing from 10% to 50% of cases. Re-audited case-notes contained more combined use of different outcome measures, with greater consensus on which measures to use. Outcome measures that were applicable across a wide range of clinical conditions were more likely to be used than symptom-specific measures, and measures that were completed by the clinician were found more often than measures completed by the service user. Conclusions: The findings show a substantial improvement in the use of outcome measures within CAMHS. These increases in use were found across different service organisations which were subject to different types of local service priorities and drivers
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