3,274 research outputs found
Comparative Study of Different Coil Geometries for Wireless Power Transfer
Inductive coupling wireless power transfer is using time-varying resonant magnetic coupling to transfer the power from the transmitting coil to receiving coil through the air gap for various application such as charging up electric vehicles. However, the main issue is that the design of the coils have led to low mutual inductance and coupling coefficient which will lower the power efficiency as the distance of air gap increases. Therefore, this research is mainly studying and comparing the design of transmitting and receiving coil such as the geometries of the coils in order to investigate the power efficiency, mutual inductance, coupling coefficient and magnetic flux. In this research, a finite element method (FEM) software, Ansoft Maxwell is used to investigate and compare the performance of various designs of coils such as spiral planar coils, square planar coils and pentagon planar coils. In addition, prototypes have been built by using PCB planar coils in shape of spiral, square and pentagon in order to compare the results and performance from simulation. In terms of result, low mutual inductance and coupling coefficient are caused by the distance of air gap. When the distance of air gap is longer, the mutual inductance and coupling coefficient are lower for the three different of coils. And also, magnetic flux is also determined by the geometries of coil where it will affect the mutual inductance which influents the coupling coefficient and power efficienc
Public service in the information age: A study of e-government in Taiwan
This article reviews the literature on e-government and discusses policy implications stemming from e-government initiatives in Taiwan. Drawing from evaluation frameworks established in previous research, this study surveys the content of 62 websites maintained by the local, secondary and central government. Study findings suggest that, while Taiwan has made significant progress in deploying e-government initiatives across different administrative levels-especially in delivering a single service window model providing one-stop service for citizens and businesses-the technology\u27s overall implementation is hampered by operational inconsistencies at the local level and differential access across the population. The article argues that to fully realise the potential of e-government, the Taiwanese government should adopt systematic measures that reach beyond service delivery to encourage wider citizen inclusion and civic participation
Media Versus Individual Frames and Horizontal Knowledge Gaps: A Study of the 2010 Health Care Reform Debate Online
This study explores the relationship between online news coverage, media use, and political knowledge in the contemporary media environment. Using the debate over health care reform legislation in 2010 as the backdrop, content analysis was performed on 1,268 stories from 10 online news outlets over a 1-month period to identify the media frames being perpetuated by more ideologically partisan versus nonpartisan media organizations. A survey was then conducted with 333 participants to investigate media audience news consumption patterns and their individual frames regarding the issue of health care reform. Results suggest that a person’s individual frames held concerning health care reform often match up with the media frames offered by his or her preferred news outlets. Consequently, a “horizontal” knowledge gap may be observed as a function of the polarization of news coverage and news consumption. Theoretical contributions and implications for later work are discussed
An optical colour sensor to monitor the marine environment
This research aims to develop a flexible, simple, low-cost, robust, deployable sensor with anti- fouling measures to detect colour change in marine environments. Such a sensor could be used to detect events, inform sampling regimes in coastal areas and act as a qualitative decision support tool. This is useful to decision makers in cities, coastal areas and globally and as gathering data can be expensive using commercial instruments a low cost sensor enables more data to be collected with a better spatial range and resolution. Detecting colour change in water could give warning of events like green tides, e.g. (right) in QuingDao, China, often caused by cyanobacteria
Urban Microclimate Impact on Vertical Building-Integrated Photovoltaic Panels
The ongoing climate crisis and turbulence on the world stage has highlighted the need for sustainability and resilience in the development and maintenance of urban areas regarding climate comfort and energy access. Local production of green energy increases both the sustainability and resilience of an area. Traditionally, photovoltaic (PV) panels are deployed wherever the amount of sunlight is highest but lowering costs for PV panels makes them cost-effective even in colder climates. Within the broader umbrella of positive energy districts, façade mounted building-integrated PV panels in urban areas additionally present unique opportunities and challenges, as factors such as wind, solar irradiance, or nearby obstructions can have either a positive or negative effect on the performance of the PV panels. In this article, we aimed to answer the question: What factors inform the optimization of vertical PV panels? To answer this, we developed a method for the optimization of placement of PV panels. By building upon readily available weather data, local panel conditions were examined, and field-driven aggregation algorithm used to guide panel placement. Performance of the resulting panel configurations were then compared to a baseline case. Results indicate that our developed method helped mitigate negative impacts of the aforementioned factors, and often improved performance over baseline
Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trials
Background: This study assessed the immunogenicity of pegvaliase (recombinant Anabaena variabilis phenylalanine [Phe] ammonia lyase [PAL] conjugated with polyethylene glycol [PEG]) treatment in adults with phenylketonuria (PKU) and its impact on safety and efficacy. Methods: Immunogenicity was assessed during induction, upward titration, and maintenance dosing regimens in adults with PKU (n = 261). Total antidrug antibodies (ADA), neutralizing antibodies, immunoglobulin (Ig) M and IgG antibodies against PAL and PEG, IgG and IgM circulating immune complex (CIC) levels, complement components 3 and 4 (C3/C4), plasma Phe, and safety were assessed at baseline and throughout the study. Pegvaliase-specific IgE levels were measured in patients after hypersensitivity adverse events (HAE). Findings: All patients developed ADA against PAL, peaking by 6 months and then stabilizing. Most developed transient antibody responses against PEG, peaking by 3 months, then returning to baseline by 9 months. Binding of ADA to pegvaliase led to CIC formation and complement activation, which were highest during early treatment. Blood Phe decreased over time as CIC levels and complement activation declined and pegvaliase dosage increased. HAEs were most frequent during early treatment and declined over time. No patient with acute systemic hypersensitivity events tested positive for pegvaliase-specific IgE near the time of the event. Laboratory evidence was consistent with immune complex-mediated type III hypersensitivity. No evidence of pegvaliase-associated IC-mediated end organ damage was noted. Interpretation: Despite a universal ADA response post-pegvaliase administration, adult patients with PKU achieved substantial and sustained blood Phe reductions with a manageable safety profile. Fund: BioMarin Pharmaceutical Inc. Keywords: Enzyme replacement therapy, Antidrug antibody, Circulating immune complex, Hypersensitivity, Phenylalanin
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