37,101 research outputs found
Contractile properties of fibroblasts derived from primary frozen shoulder and effects of TGF beta 1 stimulation
INTRODUCTION: Primary Frozen Shoulder (PFS) is a debilitating disease of unknown aetiology. There is fibrosis and contracture of the coracohumeral ligament, tissues of the rotator interval and the glenohumeral ligaments, leading to restrictive shoulder movements requiring surgical intervention [1]. Frozen shoulder has been postulated to be dupuytren’s disease of the shoulder with an association inferred since 1936. The purpose of the study was to test the hypothesis that cellular mechanisms of fibroblasts derived from primary frozen shoulder exhibited similar activity in terms of contraction and response to cytokine (transforming growth factor beta1) to fibroblasts derived from dupuytren’s disease. Understanding of cellular responses is critical to developing non surgical treatment strategies
On the VLBI measurement of the Solar System acceleration
We propose new estimates of the secular aberration drift, mainly due to the
rotation of the Solar System about the Galactic center, based on up-to-date
VLBI observations and and improved method of outlier elimination. We fit
degree-2 vector spherical harmonics to extragalactic radio source proper motion
field derived from geodetic VLBI observations spanning 1979-2013. We pay
particular attention to the outlier elimination procedure to remove outliers
from (i) radio source coordinate time series and (ii) the proper motion sample.
We obtain more accurate values of the Solar system acceleration compared to
those in our previous paper. The acceleration vector is oriented towards the
Galactic center within 7 deg. The component perpendicular to the Galactic plane
is statistically insignificant. We show that an insufficient cleaning of the
data set can lead to strong variations in the dipole amplitude and orientation,
and statistically biased results.Comment: Accepted for publication in A&
Dynamic power load simulator
Two independent models simulate dynamic and steady-state responses of electrical and electronic equipment under power load. One is resistance/capacitance/inductance network, and the other is variable resistance analog device. Resistance, inductance, and/or capacitance are selected by iterative process; time-domain response is compared with that of real equipment to select optimal values
A New Massive Type IIA Supergravity From Compactification
We consider the most general form for eleven dimensional supersymmetry
compatible with on-shell superfields. This allows for the introduction of a
conformal Spin(1,10) connection. In eleven dimensional Minkowski space this
modification is trivial and can be removed by a field redefinition, however,
upon compactification on S^1 it is possible to introduce a non-trivial `Wilson
line'. The resulting ten dimensional supergravity has massive 1-form and 3-form
potentials and a cosmological constant. This theory does not possess a
supersymmetric eightbrane soliton but it does admit a supersymmetric non-static
cosmological solution.Comment: 13 pages, phyzzx. The introduction is clarifed and a reference adde
Effect of habituation on the susceptibility of the rat to restraint ulcers
The frequency and gravity of restraint ulcers were found to significantly diminish in rats previously exposed to brief periods of immobilization. The rats' becoming habituated to restraint conditions probably explains this phenomenon
Suppression of Giant Magnetoresistance by a superconducting contact
We predict that current perpendicular to the plane (CPP) giant
magnetoresistance (GMR) in a phase-coherent magnetic multilayer is suppressed
when one of the contacts is superconducting. This is a consequence of a
superconductivity-induced magneto-resistive (SMR) effect, whereby the
conductance of the ferromagnetically aligned state is drastically reduced by
superconductivity. To demonstrate this effect, we compute the GMR ratio of
clean (Cu/Co)_nCu and (Cu/Co)_nPb multilayers, described by an ab-initio spd
tight binding Hamiltonian. By analyzing a simpler model with two orbitals per
site, we also show that the suppression survives in the presence of elastic
scattering by impurities.Comment: 5 pages, 4 figures. Submitted to PR
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