37,101 research outputs found

    Contractile properties of fibroblasts derived from primary frozen shoulder and effects of TGF beta 1 stimulation

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    INTRODUCTION: Primary Frozen Shoulder (PFS) is a debilitating disease of unknown aetiology. There is fibrosis and contracture of the coracohumeral ligament, tissues of the rotator interval and the glenohumeral ligaments, leading to restrictive shoulder movements requiring surgical intervention [1]. Frozen shoulder has been postulated to be dupuytren’s disease of the shoulder with an association inferred since 1936. The purpose of the study was to test the hypothesis that cellular mechanisms of fibroblasts derived from primary frozen shoulder exhibited similar activity in terms of contraction and response to cytokine (transforming growth factor beta1) to fibroblasts derived from dupuytren’s disease. Understanding of cellular responses is critical to developing non surgical treatment strategies

    On the VLBI measurement of the Solar System acceleration

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    We propose new estimates of the secular aberration drift, mainly due to the rotation of the Solar System about the Galactic center, based on up-to-date VLBI observations and and improved method of outlier elimination. We fit degree-2 vector spherical harmonics to extragalactic radio source proper motion field derived from geodetic VLBI observations spanning 1979-2013. We pay particular attention to the outlier elimination procedure to remove outliers from (i) radio source coordinate time series and (ii) the proper motion sample. We obtain more accurate values of the Solar system acceleration compared to those in our previous paper. The acceleration vector is oriented towards the Galactic center within 7 deg. The component perpendicular to the Galactic plane is statistically insignificant. We show that an insufficient cleaning of the data set can lead to strong variations in the dipole amplitude and orientation, and statistically biased results.Comment: Accepted for publication in A&

    La transparence des flux financiers - Propos introductifs

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    Dynamic power load simulator

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    Two independent models simulate dynamic and steady-state responses of electrical and electronic equipment under power load. One is resistance/capacitance/inductance network, and the other is variable resistance analog device. Resistance, inductance, and/or capacitance are selected by iterative process; time-domain response is compared with that of real equipment to select optimal values

    A New Massive Type IIA Supergravity From Compactification

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    We consider the most general form for eleven dimensional supersymmetry compatible with on-shell superfields. This allows for the introduction of a conformal Spin(1,10) connection. In eleven dimensional Minkowski space this modification is trivial and can be removed by a field redefinition, however, upon compactification on S^1 it is possible to introduce a non-trivial `Wilson line'. The resulting ten dimensional supergravity has massive 1-form and 3-form potentials and a cosmological constant. This theory does not possess a supersymmetric eightbrane soliton but it does admit a supersymmetric non-static cosmological solution.Comment: 13 pages, phyzzx. The introduction is clarifed and a reference adde

    Effect of habituation on the susceptibility of the rat to restraint ulcers

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    The frequency and gravity of restraint ulcers were found to significantly diminish in rats previously exposed to brief periods of immobilization. The rats' becoming habituated to restraint conditions probably explains this phenomenon

    Suppression of Giant Magnetoresistance by a superconducting contact

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    We predict that current perpendicular to the plane (CPP) giant magnetoresistance (GMR) in a phase-coherent magnetic multilayer is suppressed when one of the contacts is superconducting. This is a consequence of a superconductivity-induced magneto-resistive (SMR) effect, whereby the conductance of the ferromagnetically aligned state is drastically reduced by superconductivity. To demonstrate this effect, we compute the GMR ratio of clean (Cu/Co)_nCu and (Cu/Co)_nPb multilayers, described by an ab-initio spd tight binding Hamiltonian. By analyzing a simpler model with two orbitals per site, we also show that the suppression survives in the presence of elastic scattering by impurities.Comment: 5 pages, 4 figures. Submitted to PR
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