The Levrat Model.

<p>Gross image of esophageal tumor (animal no. 13) induced by modified Levrat model.</p

Accuracy assessment of MRI and endoscopy.

<p>A, The graph shows percent accuracy of individual scans when assessed by each technique: visual endoscopy and MRI. B, The graph compares average accuracy of each technique as evaluated by the blinded study. MRI; magnetic resonance imaging.</p

Comparative analysis of a single animal with histology, endoscopy and MRI.

<p>A, Hemotoxylin and eosin staining (magnification×10) shows histological confirmation of EAC. B, Endoscopic evaluation of the same rat. Arrow designates suspected area of tumor identified by endoscopic study participants. C, Axial MRI assessment. The arrow shows an abnormal mass on esophageal wall selected by MRI study participants. D, Coronal MRI image. Arrow identifies corresponding cross section of suspected tumor in anastomotic area of interest. MRI; magnetic resonance imaging, EAC; esophageal adenocarcinoma.</p

Statistical evaluation of individual participants in blinded study evaluating MRI and endoscopy.

<p>*Negative values indicate less than chance agreement.</p

ROC curves of MRI and endoscopic evaluation.

<p>A, ROC curve of average endoscopic reading (AUC = 0.534; SE = 0.138; asymptotic significance = 0.80; 95% confidence interval, 0.263–0.805). B, ROC curve of average MRI reading. (AUC = 0.966; SE = 0.036; asymptotic significance <.001; 95% confidence interval, 0–1.0). ROC; receiver operating characteristic, AUC; area under curve, SE; standard error.</p