Flow chart of the strategy of computer-assisted system for reminding the doctors in charge before prescribing chemotherapy.

<p>Flow chart of the strategy of computer-assisted system for reminding the doctors in charge before prescribing chemotherapy.</p

The rates of reactivation of hepatitis B and related events in patients (n = 134) with and without antiviral prophylaxis before prescribing chemotherapy.

<p>The rates of reactivation of hepatitis B and related events in patients (n = 134) with and without antiviral prophylaxis before prescribing chemotherapy.</p

Flow chart of patients with or without screening for hepatitis B surface antigen (HBsAg), antiviral prophylaxis and hepatitis B virus reactivation in overall (n = 1053) by way of the computer－assisted reminding system.

<p>Flow chart of patients with or without screening for hepatitis B surface antigen (HBsAg), antiviral prophylaxis and hepatitis B virus reactivation in overall (n = 1053) by way of the computer－assisted reminding system.</p

Demographic data of cancer patients in overall (n = 1053) who receiving chemotherapy shown by baseline characteristics, departments of doctors, cancer types and regimens of chemotherapy.

<p>ALT, alanine transaminase; HBsAg, hepatitis B surface antigen; HCV Ab, hepatitis C virus antibody. ALT, alanine transaminase; HBsAg, hepatitis B surface antigen; HCV Ab, hepatitis C virus antibody.</p><p>Demographic data of cancer patients in overall (n = 1053) who receiving chemotherapy shown by baseline characteristics, departments of doctors, cancer types and regimens of chemotherapy.</p

Clinical data of 11 patients with hepatitis B reactivation without antiviral prophylaxis before chemotherapy.

<p>ALT, alanine aminotransferase; HCC, hepatocellular carcinoma; NA, not available; C/T, chemotherapy; ETV, entecavir; LdT, telbivudine; LAM, lamivudine; TDF, tenofovir.</p><p>All patients were hepatitis B e antigen-negative.</p><p>Case 5, Case 7, Case 10 reported themselves to be inactive HBV carriers in other medical institutions.</p><p>Case 11 died within 2 days after admission without virological data and antiviral treatment.</p><p>Clinical data of 11 patients with hepatitis B reactivation without antiviral prophylaxis before chemotherapy.</p

Factors related to reactivation of hepatitis B in patients with positive of hepatitis B surface antigen (n = 134) undergoing cytotoxic chemotherapy.

<p>ALT, alanine transaminase; HBeAg, hepatitis B e-antigen; HR, hazard ratio.</p><p>Factors related to reactivation of hepatitis B in patients with positive of hepatitis B surface antigen (n = 134) undergoing cytotoxic chemotherapy.</p

Antiviral prophylactic rates in patients with positive of hepatitis B surface antigen (n = 134) undergoing chemotherapy in different cancer types.

<p>The rates of antiviral prophylaxis in doctors treating lung, breast and colorectal cancers were significantly lower in doctors treating hematological cancers (all p < 0.05).</p