Pengaruh Pelatihan terhadap Kinerja Karyawan dengan Mediasi Kepemimpinan pada Hotel Satriya Cottages Kuta Bali

Hotel Satriya Cottages dengan kelas bintang tiga merupakan salah satu USAha akomodasi bergerak dalam industry pariwisata yang mengadopsi style Tradisional Bali yang masih berupaya untuk meningkatkan kualitas pelayanan karyawan terhadap pelanggan, namun terdapat permasalahan yang timbul mengenai kinerja karyawan dikarenakan kepemimpinan yang dirasakan dari masing masing karyawan kurang optimal. Penelitian ini bertujuan untuk menguji peran kepemimpinan dalam memediasi pengaruh pelatihan terhadap kinerja karyawan hotel Satriya Cottages Kuta Bali. Pengambilan sampel penelitian ini menggunakan metode sampel jenuh. Data dikumpulkan menggunakan metode observasi, wawancara dan kuesioner. Responden dari penelitian sebanyak 75 karyawan pada hotel Satriya Cottages KutaBali.Teknik analisis data yang digunakan pada penelitian ini adalah analisis jalur. Hasil penelitian ini menunjukan bahwa (1) Pelatihan berpengaruh langsung terhadap kinerja karyawan. (2) Kepemimpinan berpengaruh langsung terhadap kinerja karyawan hotel Satriya Cottages Kuta Bali. (3) Pelatihan berpengaruh langsung terhadap kinerja karyawan dengan mediasi kepemimpinan

SIMULASI SISTEM KONTROL OPERASI ON GRID SERTA ISLANDING PEMBANGKIT LISTRIK TENAGA SURYA DI JURUSAN TEKNIK ELEKTRO UNIVERSITAS UDAYANA

An on-grid solar power plant will distribute electric power to the grid in normal conditions. But when the supply of grid outages (islanding), on-grid solar power plant also can’t operate because the loss of the reference signal that is used as a reference for the inverter in the synchronization process. So there is potential loss of power when solar power plant can be used as a substitute source of electrical energy while PLN can’t serve consumers. In this research developed a simulation model that refers to the off grid solar power plant 500 Wp in the Department of Electrical Engineering, University of Udayana and can operate on-grid and off grid when islanding in matlab simulink. In this model made operation scenario where solar power plant operates on grid at the beginning of the simulation and after that operate off-grid (not connected to the grid and supply the local load). The simulation results show the model off grid solar power plant has been able to generate a voltage of 220 V and a frequency of 50 Hz in accordance with the solar power plant at the research site. The simulation results also show model of on grid solar power plant has been able to synchronize to the low voltage grid of PLN not loaded and loaded. On/off grid solar power plant model can operate on-grid or off-grid that corresponds to the operation scenario and produce the same output. Thus solar power plant can supply.</div

Vision based indoor navigation system using external camera mounted on room

It is vital to have an excellent path planning for self-navigating mobile robots. Having considerations of the environment and objects in the space is vital in achieving a safe and effective path for robots. In indoor environments, objects and the environment are unpredictable, unlike that of in the road navigation where there are standard guidelines and road symbols. To overcome this issue, existing applications provide a solution to a certain extent. Indoor positioning systems based on Infrared, Wi-Fi and other similar techniques are existing in the industry. Also, there are solutions providing such systems with the use of a camera on the robot. Although such systems deliver the positioning of the robot and thus generating a path based on it, they fail to have an overall view of the entire space so that the generation of the path is more effective. To overcome this, the paper discusses here, a solution to the centralized vision-based navigation system for indoor robots. Our solution takes a view of the entire space beyond the immediate surroundings to the robot which was the only concern of previous solutions existing. By such a view, our solution can plan a path for the robot more effectively as it has all the objects in the space into consideration

Immune evasion in cancer: mechanistic basis and therapeutic strategies

Cancer immune evasion is a major stumbling block in designing effective anticancer therapeutic strategies. Although considerable progress has been made in understanding how cancers evade destructive immunity, measures to counteract tumor escape have not kept pace. There are a number of factors that contribute to tumor persistence despite having a normal host immune system. Immune editing is one of the key aspects why tumors evade surveillance causing the tumors to lie dormant in patients for years through “equilibrium” and “senescence” before re- emerging. In addition, tumors exploit several immunological processes such as targeting the regulatory T cell function or their secretions, antigen presentation, modifying the production of immune suppressive mediators, tolerance and immune deviation. Besides these, tumor heterogeneity and metastasis also play a critical role in tumor growth. A number of potential targets like promoting Th1, NK cell, γδ T cell responses, inhibiting Treg functionality, induction of IL-12, use of drugs including phytochemicals have been designed to counter tumor progression with much success. Some natural agents and phytochemicals merit further study. For example, use of certain key polysaccharide components from mushrooms and plants have shown possess therapeutic impact on tumor-imposed genetic instability, anti-growth signaling, replicative immortality, deregulated metabolism etc. In this review, we will discuss the advances made towards understanding the basis of cancer immune evasion and summarize the efficacy of various therapeutic measures and targets that have been developed or are being investigated to enhance tumor rejection

Electronic Structure and Bonding of Icosahedral Core-Shell Gold-Silver Nanoalloy Clusters Au_(144-x)Ag_x(SR)_60

Atomically precise thiolate-stabilized gold nanoclusters are currently of interest for many cross-disciplinary applications in chemistry, physics and molecular biology. Very recently, synthesis and electronic properties of "nanoalloy" clusters Au_(144-x)Ag_x(SR)_60 were reported. Here, density functional theory is used for electronic structure and bonding in Au_(144-x)Ag_x(SR)_60 based on a structural model of the icosahedral Au_144(SR)_60 that features a 114-atom metal core with 60 symmetry-equivalent surface sites, and a protecting layer of 30 RSAuSR units. In the optimal configuration the 60 surface sites of the core are occupied by silver in Au_84Ag_60(SR)_60. Silver enhances the electron shell structure around the Fermi level in the metal core, which predicts a structured absorption spectrum around the onset (about 0.8 eV) of electronic metal-to-metal transitions. The calculations also imply element-dependent absorption edges for Au(5d) \rightarrow Au(6sp) and Ag(4d) \rightarrow Ag(5sp) interband transitions in the "plasmonic" region, with their relative intensities controlled by the Ag/Au mixing ratio.Comment: 4 figure

Minimally invasive surgery and cancer: controversies part 1

Perhaps there is no more important issue in the care of surgical patients than the appropriate use of minimally invasive surgery (MIS) for patients with cancer. Important advances in surgical technique have an impact on early perioperative morbidity, length of hospital stay, pain management, and quality of life issues, as clearly proved with MIS. However, for oncology patients, historically, the most important clinical questions have been answered in the context of prospective randomized trials. Important considerations for MIS and cancer have been addressed, such as what are the important immunologic consequences of MIS versus open surgery and what is the role of laparoscopy in the staging of gastrointestinal cancers? This review article discusses many of the key controversies in the minimally invasive treatment of cancer using the pro–con debate format

A multi-targeted approach to suppress tumor-promoting inflammation

Cancers harbor significant genetic heterogeneity and patterns of relapse following many therapies are due to evolved resistance to treatment. While efforts have been made to combine targeted therapies, significant levels of toxicity have stymied efforts to effectively treat cancer with multi-drug combinations using currently approved therapeutics. We discuss the relationship between tumor-promoting inflammation and cancer as part of a larger effort to develop a broad-spectrum therapeutic approach aimed at a wide range of targets to address this heterogeneity. Specifically, macrophage migration inhibitory factor, cyclooxygenase-2, transcription factor nuclear factor-κB, tumor necrosis factor alpha, inducible nitric oxide synthase, protein kinase B, and CXC chemokines are reviewed as important antiinflammatory targets while curcumin, resveratrol, epigallocatechin gallate, genistein, lycopene, and anthocyanins are reviewed as low-cost, low toxicity means by which these targets might all be reached simultaneously. Future translational work will need to assess the resulting synergies of rationally designed antiinflammatory mixtures (employing low-toxicity constituents), and then combine this with similar approaches targeting the most important pathways across the range of cancer hallmark phenotypes

Climate Change Impacts on Rice Farming Systems in Northwestern Sri Lanka

Sri Lanka has achieved tremendous progress since 1950 in crop production and food availability. Yields grew at an impressive rate until leveling off in the mid-eighties. Sri Lanka's population is anticipated to grow in the coming decades, creating an ever-greater demand for food security on the household, sub-district, regional, and national scales.The agricultural sector in Sri Lanka is vulnerable to climate shocks. An unusual succession of droughts and floods from 2008 to 2014 has led to both booms and busts in agricultural production, which were reflected in food prices. In both instances, the majority of farmers and consumers were adversely affected.At present the rice-farming systems are under stress due to inadequate returns for the farmers and difficulty in coping with shocks due to climate, pests, and diseases, and prices for produce. There are government price-support mechanisms, fertilizer-subsidy schemes, and crop insurance schemes, but the levels of the supports are modest and often do not effectively reach the farmers