Solar driven lasers for power satellite applications

The technological feasibility of using multimagawatt lasers for space power transmission is discussed. Candidate lasers include electric discharge lasers, direct optically pumped lasers, and free electron lasers

South Dakota Grasslands, Their Condition and Management

Statewide surveys of South Dakota grasslands have been made in 1940, 1942, and 1946. The stocking rates presented on the map (center pages) were determined from the 1946 survey, based upon the past ten years\u27 actual use-grazing records from representative farms and ranches. The range and pasture condition method of study was introduced into the 1946 resurvey of South Dakota grassland. The condition approach is much more usable by stockmen and agricultural workers alike than former methods of making grassland inventories. The 1946 inventory of range and pasture condition shows South Dakota grasslands are near the peak of productivity. Above-average rainfall is largely responsible for this condition. When the precipitation cycle becomes less favorable and dry years come and they surely will-then only good management of our grasslands can maintain their productivity and prevent the unfavorable conditions of the mid-thirties. Further studies and follow-up surveys will be made periodically to keep abreast of changes in condition and stocking rates for South Dakota grassland

In Vivo Analysis of Conserved C. elegans Tomosyn Domains

Neurosecretion is critically dependent on the assembly of a macromolecular complex between the SNARE proteins syntaxin, SNAP-25 and synaptobrevin. Evidence indicates that the binding of tomosyn to syntaxin and SNAP-25 interferes with this assembly, thereby negatively regulating both synaptic transmission and peptide release. Tomosyn has two conserved domains: an N-terminal encompassing multiple WD40 repeats predicted to form two β-propeller structures and a C-terminal SNARE-binding motif. To assess the function of each domain, we performed an in vivo analysis of the N- and C- terminal domains of C. elegans tomosyn (TOM-1) in a tom-1 mutant background. We verified that both truncated TOM-1 constructs were transcribed at levels comparable to rescuing full-length TOM-1, were of the predicted size, and localized to synapses. Unlike full-length TOM-1, expression of the N- or C-terminal domains alone was unable to restore inhibitory control of synaptic transmission in tom-1 mutants. Similarly, co-expression of both domains failed to restore TOM-1 function. In addition, neither the N- nor C-terminal domain inhibited release when expressed in a wild-type background. Based on these results, we conclude that the ability of tomosyn to regulate neurotransmitter release in vivo depends on the physical integrity of the protein, indicating that both N- and C-terminal domains are necessary but not sufficient for effective inhibition of release in vivo