2,681 research outputs found
From a Mirage to an Oasis: Narcissism, Perceived Creativity, and Creative Performance
We examine the link between narcissism and creativity at the individual, relational, and group levels of analysis. We find that narcissists are not necessarily more creative than others but they think they are, and they are adept at convincing others to agree with them. In the first study, narcissism was positively associated with self-rated creativity, despite the fact that blind coders saw no difference between the creative products offered by those low and high on narcissism. In a second study, more narcissistic individuals asked to pitch creative ideas to a target person were judged by the targets as being more creative than were less narcissistic individuals, in part because narcissists were more enthusiastic. Finally, in a study of group creativity, we find evidence of a curvilinear effect: having more narcissists is better for generating creative outcomes (but having too many provides diminishing returns)
Distributive Justice Beliefs and Group Idea Generation: Does a Belief in Equity Facilitate Productivity?
The equity rule is favored by groups that emphasize productivity, but there is limited support for the notion that equity actually facilitates productivity in groups (Deutsch, 1985). We propose that the relationship between equity and productivity may depend on whether individual group members have an independent or interdependent self-construal. This prediction was tested in an experiment in which groups endorsed either an equity rule or an equality rule for distributing resources and then generated ideas as a group. The results showed that equity facilitated productivity (e.g., the number of ideas generated) but only in groups whose members had been primed with an independent self-construal. The results of both self-report and video-tape data support competition as the mechanism that explains this productivity gain. This work contributes to research on both distributive justice and small group performance by specifying more clearly the conditions under which a belief in equity will stimulate productivity
Outside Advantage: Can Social Rejection Fuel Creative Thought?
Eminently creative people working in fields as disparate as Physics and Literature refer to the experience of social rejection as fuel for creativity. Yet, the evidence of this relationship is anecdotal, and the psychological process that might explain it is as yet unknown. We theorize that the experience of social rejection may indeed stimulate creativity but only for individuals with an independent self-concept. In three studies, we show that individuals who hold an independent self-concept performed more creatively following social rejection relative to inclusion. We also show that this boost in creativity is mediated by a differentiation mindset, or salient feelings of being different from others. Future research might investigate how the self-concept, for example various cultural orientations, may shape responses to social rejection by mitigating some of the negative consequences of exclusion and potentially even motivating creative exploration
Geographic Variations and the associated Factors in adherence to and Persistence With adjuvant Hormonal therapy For the Privately insured Women aged 18-64 With Breast Cancer in Texas
The purpose of this study is to examine the geographical patterns of adjuvant hormonal therapy adherence and persistence and the associated factors in insured Texan women aged 18-64 with early breast cancer. A retrospective cohort study was conducted using 5-year claims data for the population insured by the Blue Cross Blue Shield of Texas (BCBSTX). Women diagnosed with early breast cancer who were taking tamoxifen or aromatase inhibitors (AIs) for adjuvant hormonal therapy with at least one prescription claim were identified. Adherence to adjuvant hormonal therapy and persistence with adjuvant hormonal therapy were calculated as outcome measures. Women without a gap between two consecutively dispensed prescriptions of at least 90 days were considered to be persistently taking the medications. Patient-level multivariate logistic regression models with repeated regional-level adjustments and a Cox proportional hazards model with mixed effects were used to determine the geographical variations and patient-, provider-, and area-level factors that were associated with adjuvant hormonal therapy adherence and persistence. Of the 938 women in the cohort, 627 (66.8%) initiated adjuvant hormonal therapy. Most of the smaller HRRs have significantly higher or lower rates of treatment adherence and persistence rates relative to the median regions. The use of AHT varies substantially from one geographical area to another, especially for adherence, with an approximately two-fold difference between the lowest and highest areas, and area-level factors were found to be significantly associated with the compliance of AHT. There are geographical variations in AHT adherence and persistence in Texas. Patient-level and area-level factors have significant associations explaining these patterns
Geographic Variations and the associated Factors in adherence to and Persistence With adjuvant Hormonal therapy For the Privately insured Women aged 18-64 With Breast Cancer in Texas
The purpose of this study is to examine the geographical patterns of adjuvant hormonal therapy adherence and persistence and the associated factors in insured Texan women aged 18-64 with early breast cancer. A retrospective cohort study was conducted using 5-year claims data for the population insured by the Blue Cross Blue Shield of Texas (BCBSTX). Women diagnosed with early breast cancer who were taking tamoxifen or aromatase inhibitors (AIs) for adjuvant hormonal therapy with at least one prescription claim were identified. Adherence to adjuvant hormonal therapy and persistence with adjuvant hormonal therapy were calculated as outcome measures. Women without a gap between two consecutively dispensed prescriptions of at least 90 days were considered to be persistently taking the medications. Patient-level multivariate logistic regression models with repeated regional-level adjustments and a Cox proportional hazards model with mixed effects were used to determine the geographical variations and patient-, provider-, and area-level factors that were associated with adjuvant hormonal therapy adherence and persistence. Of the 938 women in the cohort, 627 (66.8%) initiated adjuvant hormonal therapy. Most of the smaller HRRs have significantly higher or lower rates of treatment adherence and persistence rates relative to the median regions. The use of AHT varies substantially from one geographical area to another, especially for adherence, with an approximately two-fold difference between the lowest and highest areas, and area-level factors were found to be significantly associated with the compliance of AHT. There are geographical variations in AHT adherence and persistence in Texas. Patient-level and area-level factors have significant associations explaining these patterns
H-alpha kinematics of S4G spiral galaxies-II. Data description and non-circular motions
We present a kinematical study of 29 spiral galaxies included in the Spitzer
Survey of Stellar Structure in Galaxies, using Halpha Fabry-Perot data obtained
with the Galaxy Halpha Fabry-Perot System instrument at the William Herschel
Telescope in La Palma, complemented with images in the R-band and in Halpha.
The primary goal is to study the evolution and properties of the main
structural components of galaxies through the kinematical analysis of the FP
data, complemented with studies of morphology, star formation and mass
distribution. In this paper we describe how the FP data have been obtained,
processed and analysed. We present the resulting moment maps, rotation curves,
velocity model maps and residual maps. Images are available in FITS format
through the NASA/IPAC Extragalactic Database and the Centre de Donn\'ees
Stellaires. With these data products we study the non-circular motions, in
particular those found along the bars and spiral arms. The data indicate that
the amplitude of the non-circular motions created by the bar does not correlate
with the bar strength indicators. The amplitude of those non-circular motions
in the spiral arms does not correlate with either arm class or star formation
rate along the spiral arms. This implies that the presence and the magnitude of
the streaming motions in the arms is a local phenomenon.Comment: 23 pages, 14 figures, without appendices, accepted to be published in
MNRA
Erratum: "Prenatal Organophosphate Pesticide Exposure and Traits Related to Autism Spectrum Disorders in a Population Living in Proximity to Agriculture".
[This corrects the article DOI: 10.1289/EHP2580.]
ArhGAP9, a novel MAP kinase docking protein, inhibits Erk and p38 activation through WW domain binding
We have identified human ArhGAP9 as a novel MAP kinase docking protein that interacts with Erk2 and p38α through complementarily charged residues in the WW domain of ArhGAP9 and the CD domains of Erk2 and p38α. This interaction sequesters the MAP kinases in their inactive states through displacement of MAP kinase kinases targeting the same sites. While over-expression of wild type ArhGAP9 caused MAP kinase activation by the epidermal growth factor receptor (EGFR) to be suppressed and preserved the actin stress fibres in quiescent Swiss 3T3 fibroblasts, over-expression of an ArhGAP9 mutant defective in MAP kinase binding restored EGFR-induced MAP kinase activation and resulted in significant disruption of the stress fibres, consistent with the role of Erk activation in disassembly of actin stress fibres. The interaction between ArhGAP9 and the MAP kinases represents a novel mechanism of cross-talk between Rho GTPase and MAP kinase signaling
Hypoactive Sexual Desire Disorder:International Society for the Study of Women's Sexual Health (ISSWSH) Expert Consensus Panel Review
The objective of the International Society for the Study of Women\u27s Sexual Health expert consensus panel was to develop a concise, clinically relevant, evidence-based review of the epidemiology, physiology, pathogenesis, diagnosis, and treatment of hypoactive sexual desire disorder (HSDD), a sexual dysfunction affecting approximately 10% of adult women. Etiologic factors include conditions or drugs that decrease brain dopamine, melanocortin, oxytocin, and norepinephrine levels and augment brain serotonin, endocannabinoid, prolactin, and opioid levels. Symptoms include lack or loss of motivation to participate in sexual activity due to absent or decreased spontaneous desire, sexual desire in response to erotic cues or stimulation, or ability to maintain desire or interest through sexual activity for at least 6 months, with accompanying distress. Treatment follows a biopsychosocial model and is guided by history and assessment of symptoms. Sex therapy has been the standard treatment, although there is a paucity of studies assessing efficacy, except for mindfulness-based cognitive behavior therapy. Bupropion and buspirone may be considered off-label treatments for HSDD, despite limited safety and efficacy data. Menopausal women with HSDD may benefit from off-label testosterone treatment, as evidenced by multiple clinical trials reporting some efficacy and short-term safety. Currently, flibanserin is the only Food and Drug Administration-approved medication to treat premenopausal women with generalized acquired HSDD. Based on existing data, we hypothesize that all these therapies alter central inhibitory and excitatory pathways. In conclusion, HSDD significantly affects quality of life in women and can effectively be managed by health care providers with appropriate assessments and individualized treatments
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