25 research outputs found
2 supplementary figures from Loss of <i>runx1</i> function results in B cell immunodeficiency but not T cell in adult zebrafish
They are two supplementary figures to support the main manuscript
Associations of Lp-PLA<sub>2</sub> mass with intracranial and extracranial arterial stenosis.
<p>OR, odds ratio. Model I adjusted for age and sex. Model II adjusted for age, sex, BMI, hypertension duration, current smoking and drinking status, diabetes, LDL, HDL, plasma glucose, mean arterial pressure, heart rate, neutrophil account, urine albumin creatinine ratio, serum creatinine, anti-hypertensive treatment, and statin use. The odds ratio expressed the risk in the ICAS and ECAS group compared with the non-stenosis group. Isolated ECAS, extracranial arterial stenosis only; Isolated ICAS, intracranial arterial stenosis only; COMB, combined extra- and intracranial arterial stenosis. Complex ICAS, intracranial arterial stenosis no matter how was the extracranial arteries; Hypertension duration, neutrophil account, serum creatinine, urine albumin creatinine ratio and Lp-PLA<sub>2</sub> are log-transformed.</p><p>Associations of Lp-PLA<sub>2</sub> mass with intracranial and extracranial arterial stenosis.</p
Prevalence of moderate to severe ECAS and ICAS (%) (A) and distribution of ICAS vessels (B) according to tertiles of Lp-PLA<sub>2</sub>.
<p>ECAS, extracranial arterial stenosis; ICAS, intracranial arterial stenosis; Lp-PLA2, Lipoprotein-associated phospholipase A<sub><b>2</b></sub>.</p
Gastric Cancer Staging with Dual Energy Spectral CT Imaging
<div><p>Purpose</p><p>To evaluate the clinical utility of dual energy spectral CT (DEsCT) in staging and characterizing gastric cancers.</p><p>Materials and Methods</p><p>96 patients suspected of gastric cancers underwent dual-phasic scans (arterial phase (AP) and portal venous phase (PP)) with DEsCT mode. Three types of images were reconstructed for analysis: conventional polychromatic images, material-decomposition images, and monochromatic image sets with photon energies from 40 to 140 keV. The polychromatic and monochromatic images were compared in TNM staging. The iodine concentrations in the lesions and lymph nodes were measured on the iodine-based material-decomposition images. These values were further normalized against that in aorta and the normalized iodine concentration (nIC) values were statistically compared. Results were correlated with pathological findings.</p><p>Results</p><p>The overall accuracies for T, N and M staging were (81.2%, 80.0%, and 98.9%) and (73.9%, 75.0%, and 98.9%) determined with the monochromatic images and the conventional kVp images, respectively. The improvement of the accuracy in N-staging using the keV images was statistically significant (p<0.05). The nIC values between the differentiated and undifferentiated carcinoma and between metastatic and non-metastatic lymph nodes were significantly different both in AP (p = 0.02, respectively) and PP (p = 0.01, respectively). Among metastatic lymph nodes, nIC of the signet-ring cell carcinoma were significantly different from the adenocarcinoma (p = 0.02) and mucinous adenocarcinoma (p = 0.01) in PP.</p><p>Conclusion</p><p>The monochromatic images obtained with DEsCT may be used to improve the N-staging accuracy. Quantitative iodine concentration measurements may be helpful for differentiating between differentiated and undifferentiated gastric carcinoma, and between metastatic and non-metastatic lymph nodes.</p></div
Accuracies, sensitivities and specificities for the distinction of N0 vs. N+ using kVp images (Group A) and optimal monochromatic images (Group B) with histological examination as the reference standard among patients with non metastatic disease.
<p>Accuracies, sensitivities and specificities for the distinction of N0 vs. N+ using kVp images (Group A) and optimal monochromatic images (Group B) with histological examination as the reference standard among patients with non metastatic disease.</p
Receiver operating characteristic curves for differentiating metastatic and non-metastatic lymph node in portal phase.
<p>Receiver operating characteristic curves for differentiating metastatic and non-metastatic lymph node in portal phase.</p
Water-based material decomposition images for a 62-year-old man with signet ring cell carcinoma obtained with dual energy spectral scan mode.
<p>Water-based material decomposition images for a 62-year-old man with signet ring cell carcinoma obtained with dual energy spectral scan mode.</p
Same patient as Figure 3.
<p>KVp image in portal phase maintained a relatively sharp tumor contour and a clear stomach fat plane (arrow heads), staged as T2.</p
Clinical characteristics of the 96 patients.
<p>Clinical characteristics of the 96 patients.</p
Same patient as Figure 3.
<p>Monochromatic image in portal phase demonstrated striation enhancement of blurring and wide reticular strands surrounding the outer border (arrow heads) of the tumor staged as T3 which was proved by histology.</p