Perancangan Dan Pembuatan Aplikasi Ecommerce Pada Toko Agung Jaya

Perkembangan teknologi pada saat ini telah berkembang secara pesat. Dimana hampir semua kegiatan dapat dilakukan pada dunia maya, misalnya melakukan transaksi pembayaran, pembelian barang, pemesanan tiket, baik tiket pesawat maupun tiket kereta api, dan lainnya.Di jaman sekarang ini penjualan secara online sudah banyak. Hal ini dikarenakan untuk membuka suatu USAha online lebih mudah dan murah dari pada membuka USAha disuatu tempat yang berbentuk bangunan. Selain itu, dengan cara berjualan online orang akan lebih banyak mengetahui barang apa saja yang dijual, karena semua orang dapat melihat tanpa harus mendatangi tempat itu.Berdasarkan hasil pengujian aplikasi yang telah dibuat, aplikasi dapat menampilkan data barang yang dijual beserta promo yang ditawarkan. Selain itu aplikasi ini mempunyai fitur konfirmasi account untuk mengaktifkan account dan kirim detail order

Standard Model Higgs Searches at the LHC

An overview of the searches for the Standard Model Higgs boson at the LHC is presented. The main Higgs production and decay modes that have been studied are introduced, and the analysis techniques and the recent developments done by the ATLAS and CMS experiments are described. Some preliminary results from current studies are included. The discovery potential within the first few years of physics running is evaluated

A Prechop Technique Using a Reverse Chopper

<p><i>Purpose</i>: To describe a manual prechop technique for splitting the nucleus of the lens using a recently developed reverse chopper. <i>Methods</i>: During the process, the reverse chopper and the Nagahara chopper are placed diagonally in the peripheral area of the nucleus of the lens after capsulorhexis. The reverse chopper and the Nagahara chopper then are pushed horizontally toward each other so they meet at the center of the lens to split the nucleus of lens into 2 parts. <i>Results</i>: In all cases, the reverse chopper was effective during the prechop procedure for hard nuclei, the nucleus of the lens remained <i>in situ</i> during the chopping process, and the reverse chopper did not retract the suspensory ligament in patients in whom the ligament was fragile. During the prechop procedure, no capsule breakage occurred, and the time and energy required for effective phacoemulsification were reduced significantly. <i>Conclusions</i>: The prechop technique using the reverse chopper can be applied for cases with grade III–V nuclei, overripe nuclei, and fragile suspensory ligaments. The procedure is simple, and the learning curve is not steep.</p

Odd–Even Glass Transition Temperatures in Network-Forming Ionic Glass Homologue

Odd–even effects, the non-monotonic dependency of physical properties on odd/even structural units, are widely observed in homologous series of crystalline materials. However, such alternation is not expected for molecular amorphous materials. Herein, we report the synthesis of a class of network-forming ionic glasses using multivalent ammonium cations and citrate anions. The glass transition temperatures of these amorphous solids show an alternating pattern with increasing backbone length. To understand the phenomenon’s molecular origin, we performed incoherent elastic neutron scattering measurements of the nanosecond atomic dynamics. Our results suggest that the molecules’ mobility, and thus the glass transition temperature, correlates with their structural symmetry

Pressure-Induced Phase Transition of Hydrogen Storage Material Hydrazine Bisborane: Evolution of Dihydrogen Bonds

We report the high-pressure behavior of dihydrogen-bonded hydrogen storage material hydrazine bisborane (BH₃N₂H₄BH₃, HBB) via in situ angle-dispersive X-ray diffraction (ADXRD) and Raman spectroscopy in a diamond anvil cell up to 2.0 GPa. A reversible phase transition at 0.4 GPa was confirmed by ADXRD experiments. The Rietveld refinement showed the high-pressure phase was consistent with the crystal structure of α′-phase (low-temperature phase). Through the analysis of structure changes, Raman spectroscopy, and the Hirshfeld surface, we studied the evolution of dihydrogen bonds under high pressure and attributed the pressure-induced phase transition to the distortion and rotation of the NH₂–NH₂ group. This work will further the understanding of the characteristics of dihydrogen bonds and provide some contribution to future hydrogen storage applications of HBB

Experimental and Kinetic Study on Ignition Delay Times of Di‑<i>n</i>‑butyl Ether at High Temperatures

Ignition delay times of di-<i>n</i>-butyl ether (DBE)/oxygen mixtures diluted with argon were measured behind reflected shock waves for the pressures between 1.2 and 4 bar, the temperatures between 1100 and 1570 K, and the equivalence ratios of 0.5, 1.0, and 1.5. A recently developed DBE model was employed to simulate the autoignition process of the homogeneous mixture. Comparisons between the measured and calculated ignition delay times indicate that the model yields fairly good agreement under all test conditions. Results show that the ignition delay time increases with the decrease of the pressure and the increase of the dilution ratio. The ignition delay time demonstrates a strong negative dependence upon the equivalence ratio at high temperatures, and the difference among the ignition delay times tends to decrease when the temperature is decreased. Sensitivity analysis reveals the importance of H-abstraction reactions and decomposition of α fuel radicals in the ignition process of DBE. Reaction pathway analysis confirms that the consumption of DBE is dominated by the H-abstraction reactions at lower temperatures, and when the temperature is increased, the unimolecular decomposition reactions become more important. Comparisons of ignition delay times as well as fuel consumption and radical growth history of DBE to dimethyl ether (DME) and diethyl ether (DEE) for given equivalence ratios indicate that DBE has the strongest overall reactivity, although the reactant concentration of DBE is the lowest

Shock-Induced Ordering in a Nano-segregated Network-Forming Ionic Liquid

Understanding shock­wave-induced physical and chemical changes of impact-absorbing materials is an important step toward the rational design of materials that mitigate the damage. In this work, we report a series of network-forming ionic liquids (NILs) that possess an intriguing shock­wave absorption property upon laser-induced shock­wave. Micro­structure analysis by X-ray scattering suggests nano-segregation of alkyl side chains and charged head groups in NILs. Further post-shock observations indicate changes in the low-<i>Q</i> region, implying that the soft alkyl domain in NILs plays an important role in absorbing shock­waves. Interestingly, we observe a shock-induced ordering in the NIL with the longest (hexyl) side chain, indicating that both nano-segregated structure and shock-induced ordering contribute to NIL’s shock­wave absorption performance

Fluoro-Polymer@BaTiO₃ Hybrid Nanoparticles Prepared via RAFT Polymerization: Toward Ferroelectric Polymer Nanocomposites with High Dielectric Constant and Low Dielectric Loss for Energy Storage Application

Polymer nanocomposites with high energy density and low dielectric loss are highly desirable in electronic and electric industry. Achieving the ability to tailor the interface between polymer and nanoparticle is the key issue to realize desirable dielectric properties and high energy density in the nanocomposites. However, the understanding of the role of interface on the dielectric properties and energy density of polymer nanocomposites is still very poor. In this work, we report a novel strategy to improve the interface between the high dielectric constant nanoparticles (i.e., BaTiO₃) and ferroelectric polymer [i.e., poly­(vinylidene fluoride-co-hexafluoro propylene)]. Core–shell structured BaTiO₃ nanoparticles either with different shell thickness or with different molecular structure of the shell were prepared by grafting two types of fluoroalkyl acrylate monomers via surface-initiated reversible addition–fragmentation chain transfer (RAFT) polymerization. The dielectric properties and energy storage capability of the corresponding nanocomposites were investigated by broadband dielectric spectroscopy and electric displacement-electric field loop measurement, respectively. The results show that high energy density and low dielectric loss are successfully realized in the nanocomposites. Moreover, the energy storage densities of the P­(VDF-HFP)-based nanocomposites could be tailored by adjusting the structure and thickness of the fluoro-polymer shell. The approach described is applicable to a wide range of nanoparticles and polymer matrix, thereby providing a new route for preparing polymer-based nanocomposites used in electronic and electric industry

Core@Double-Shell Structured BaTiO₃–Polymer Nanocomposites with High Dielectric Constant and Low Dielectric Loss for Energy Storage Application

Polymer nanocomposites with high dielectric constant have extensive applications in the electronic and electrical industry because of ease of processing and low cost. Blending and <i>in situ</i> polymerization are two conventional methods for the preparation of polymer nanocomposites. However, the resulting nanocomposites, particularly highly filled nanocomposites, generally have some disadvantages such as high dielectric loss and low dielectric constant and thus show low energy density and low energy efficiency. Here we developed a core@double-shell strategy to prepare barium titanate (BT)-based high performance polymer nanocomposites, in which the first shell is hyperbranched aromatic polyamide (HBP) and the second shell is poly­(methyl methacrylate) (PMMA). This method utilized the advantages of both polymer shells, resulting in superior dielectric property which cannot be achieved in nanocomposites prepared by the conventional blending methods. It is found that, compared with the conventional solution blended BT/PMMA nanocomposites, the core@double-shell structured BT@HBP@PMMA nanocomposites had higher dielectric constant and lower dielectric loss. The energy densities of BT@HBP@PMMA nanocomposites were higher than that of BT/PMMA nanocomposites accordingly. The dielectric response of the nanocomposites was analyzed, and the mechanisms resulting in the higher dielectric constant and lower dielectric loss in BT@HBP@PMMA nanocomposites were proposed. This study suggests that the core@double-shell strategy shows strong potential for preparing polymer nanocomposites with desirable dielectric properties

Table1_Identification of pyroptosis-associated genes with diagnostic value in calcific aortic valve disease.docx

BackgroundCalcific aortic valve disease (CAVD) is one of the most prevalent valvular diseases and is the second most common cause for cardiac surgery. However, the mechanism of CAVD remains unclear. This study aimed to investigate the role of pyroptosis-related genes in CAVD by performing comprehensive bioinformatics analysis.MethodsThree microarray datasets (GSE51472, GSE12644 and GSE83453) and one RNA sequencing dataset (GSE153555) were obtained from the Gene Expression Omnibus (GEO) database. Pyroptosis-related differentially expressed genes (DEGs) were identified between the calcified and the normal valve samples. LASSO regression and random forest (RF) machine learning analyses were performed to identify pyroptosis-related DEGs with diagnostic value. A diagnostic model was constructed with the diagnostic candidate pyroptosis-related DEGs. Receiver operating characteristic (ROC) curve analysis was performed to estimate the diagnostic performances of the diagnostic model and the individual diagnostic candidate genes in the training and validation cohorts. CIBERSORT analysis was performed to estimate the differences in the infiltration of the immune cell types. Pearson correlation analysis was used to investigate associations between the diagnostic biomarkers and the immune cell types. Immunohistochemistry was used to validate protein concentration.ResultsWe identified 805 DEGs, including 319 down-regulated genes and 486 up-regulated genes. These DEGs were mainly enriched in pathways related to the inflammatory responses. Subsequently, we identified 17 pyroptosis-related DEGs by comparing the 805 DEGs with the 223 pyroptosis-related genes. LASSO regression and RF algorithm analyses identified three CAVD diagnostic candidate genes (TREM1, TNFRSF11B, and PGF), which were significantly upregulated in the CAVD tissue samples. A diagnostic model was constructed with these 3 diagnostic candidate genes. The diagnostic model and the 3 diagnostic candidate genes showed good diagnostic performances with AUC values >0.75 in both the training and the validation cohorts based on the ROC curve analyses. CIBERSORT analyses demonstrated positive correlation between the proportion of M0 macrophages in the valve tissues and the expression levels of TREM1, TNFRSF11B, and PGF.ConclusionThree pyroptosis-related genes (TREM1, TNFRSF11B and PGF) were identified as diagnostic biomarkers for CAVD. These pyroptosis genes and the pro-inflammatory microenvironment in the calcified valve tissues are potential therapeutic targets for alleviating CAVD.</p