Ethosomes Loaded with Cryptotanshinone for Acne Treatment through Topical Gel Formulation - Fig 2

<p><i>In vitro</i> transdermal profiles (A) and skin deposition (B) of ethosomal gel and conventional gel, (n = 6) **, P<0.01.</p

Effect of cryptotanshinone loaded ethosomal gel on the histopathology in the rabbit ear acne model induced by oleic acid.

<p>A: normal rabbit ear, B: acne model treated by blank ethosomal gel, C: conventional cryptotanshinone gel, D: cryptotanshinone loaded ethosomal gel. (400×).</p

Ethosomes Loaded with Cryptotanshinone for Acne Treatment through Topical Gel Formulation - Fig 3

<p>Influence of cryptotanshinone loaded ethosomal gel on epidermis thickness (A) and lymphatic cell numbers in a radon area (10 μm×10 μm) of dermis (B). #P>0.05, *P<0.05, **P<0.01.</p

Images of cryptotanshinone loaded ethosomes.

<p>Images of cryptotanshinone loaded ethosomes.</p

Formulation of ethosomes.

<p>Formulation of ethosomes.</p

Enzyme Mediated Increase in Methanol Production from Photoelectrochemical Cells and CO₂

While success has been shown in utilizing photocatalytic systems to reduce CO₂ in water, most of these studies have yielded formic acid as the major product with trace amounts of formaldehyde or methanol. One reason for this is the strong equilibrium of formaldehyde toward the hydrate methanediol. To increase methanol yields from CO₂, we show here the combined use of the biological catalyst alcohol dehydrogenase (ADH) from <i>Saccharomyces cerevisiae</i> with CO₂ reduction products obtained from photoelectrochemical cells (PEC). We first show that ADH can reduce very low micromolar amounts of formaldehyde in solution. Upon adding ADH to the PEC products, a rapid three- to four-fold gain in methanol production was observed, which we also attribute to the lack of back reaction by the enzyme. Lastly, because formaldehyde dehydrogenase (FalDH) showed very low reactivity with formate, the addition of FalDH and ADH to the PEC products demonstrated no difference in methanol yields as compared to ADH alone

Origin of the Volume Contraction during Nanoporous Gold Formation by Dealloying for High-Performance Electrochemical Applications

Nanoporous metals used in various electrochemical applications including electrochemical actuators, electrocatalysts, supercapacitors, and batteries exhibit an irreversible volume shrinkage during their formation by dealloying, the origin of which remains obscure. Here we use dilatometry techniques to measure the irreversible shrinkage in nanoporous Au <i>in situ</i> during electrochemical dealloying. A linear contraction up to ∼9% was recorded. To identify the origin of this dimensional change, we borrow the time-dependent isothermal shrinkage model from sintering theory, which we use to fit the dimensional changes measured in our nanoporous Au during dealloying. This shrinkage model suggests that bulk transport through plastic flow is the primary mass transport mechanism responsible for the material contraction in dealloying. Based on the current understanding of the mechanism of porosity formation in dealloying, mass transport through surface diffusion of undissolved materials is critical in the process. The present work sheds new light in the sense that bulk transport through plastic flow seems also to play an important role in dealloying

Data_Sheet_1_Case report: A case of corneal deposits between binocular descemet membrane and corneal endothelial layer after small-incision lenticule extraction (SMILE) followed by HPV vaccine.pdf

BackgroundDeposits located between the Descemet memberane and the corneal endothelial layer in both eyes has not yet been reported after SMILE.Case reportGrayish white fine deposits was found between the Descemet memberane and the corneal endothelial layer in both eyes of the patient's cornea, and no other abnormalities were observed in the anterior and posterior segments of patient's eyes with ophthalmic examination instrument. However, the visual acuity of patient remained unchanged. Significantly, the patient had a sister who had undergone the same procedure a year earlier without any complications. After careful questioning, we learned that the patient received the 9-valent human papillomavirus (HPV) vaccine on the third post-operative day without any other special experiences. We performed immunological examination and genetic testing on the patient. The results of immunological examination of patient showed no obvious abnormality, which was consistent with the routine trend after vaccination. In particular, a homozygous variation of the ARSG gene was found in the patient and her sister.ConclusionThere are two possible causes of corneal changes in patients. The first is IGA elevation caused by vaccination, deposited in the cornea. Second, the ARSG gene mutation of the patient leads to a potential congenital corneal dystrophy, and clinical manifestations occur under the stimulation of the vaccine.</p

Additional file 1 of The clinical characteristics and treatment of ovarian malignant mesoderm mixed tumor: a systematic review

Additional file 1

Additional file 2 of The clinical characteristics and treatment of ovarian malignant mesoderm mixed tumor: a systematic review

Additional file 2