24 research outputs found

    Additional file 1 of COVID-19 vaccination strategies in settings with limited rollout capacity: a mathematical modelling case study in Sierra Leone

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    Additional file 1: S1. Model Structure. S1.1. Modelling transmission. S1.2. Fitting to the basic reproduction number. S1.3. Tracking the effective reproduction number. S1.4. Modification of severe outcome projections with high-risk group. S2. Parameter Estimates. S2.1. Parameters associated with transmission. S2.2. Vaccine effectiveness. S2.3. Infection-derived immunity. S2.4. Severe outcome projections. S2.5. Characterising high-risk groups. S3. Model Fit. S4. Sensitivity Analysis. S4.1. Outbreak of a new immune-escape variant. S4.2. Prioritisation of a double-dose vaccine. S4.3. Prioritisation of a larger number of doses. S4.4. Increased vaccine hesitancy in pregnant women. S4.5. Reduced vaccine effectiveness in older adults. S4.6. Reduced vaccine effectiveness in older adults and adults with comorbidities. S4.7. Increased or decreased risk of high-risk groups. S4.8. Influence of pre-existing infection-derived immunity

    Factors associated with presenting more than once vs once, for presentations associated with intimate partner violence or non-partner sexual violence.<sup>†</sup>

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    <p><sup>†</sup> Patients presenting more than once since Jan 2008, for those presentations from Aug 2010 to April 2013 to the FSC. *Multiple variable analyses of presentations to the Family Support Centre adjusted for age, sex, type of violence, type of medical care, source of referral, and year. Patients presenting for past violence were not included as data were not included on referral source. These analyses were conducted on the sample of 4,903 presentations with complete data on these variables. **Horizontal bars indicate 95% confidence intervals.</p

    Factors associated with presentation <72 hours vs ≥72 hours after sexual violence.

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    <p>* Multiple variable analyses of timely for presentations following sexual violence (both non-partner and intimate partner violence) adjusted for age, sex, first or repeat presentation, perpetrator, place of residence, source of referral, treatment facility, and year. These analyses were conducted on the sample of 1,355 presentations with complete data on these variables. **Horizontal bars indicate 95% confidence intervals.</p

    Transmission parameters for outbreaks of avian influenza H5N1 infection.

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    a<p>Mean number of secondary cases infected by a single index case in an exposed population of size 5, CI denotes confidence interval.</p>b<p>Mean number of zoonotic cases in an exposed population of size 5.</p>c<p>AIC<sub>C</sub> denotes Akaike Information Criterion adjusted for small sample size. This indicates the percent probability that the model is the best amongst those considered.</p
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