4 research outputs found
Monitoring wafers’ geometric quality using an additive Gaussian process model
<div><p>ABSTRACT</p><p>The geometric quality of a wafer is an important quality characteristic in the semiconductor industry. However, it is difficult to monitor this characteristic during the manufacturing process due to the challenges created by the complexity of the data structure. In this article, we propose an Additive Gaussian Process (AGP) model to approximate a standard geometric profile of a wafer while quantifying the deviations from the standard when a manufacturing process is in an in-control state. Based on the AGP model, two statistical tests are developed to determine whether or not a newly produced wafer is conforming. We have conducted extensive numerical simulations and real case studies, the results of which indicate that our proposed method is effective and has potentially wide application.</p></div
Logistic regression for crystal growth process modeling through hierarchical nonnegative garrote-based variable selection
<p>Single-crystal silicon ingots are produced from a complex crystal growth process. Such a process is sensitive to subtle process condition changes, which may easily become failed and lead to the growth of a polycrystalline ingot instead of the desired monocrystalline ingot. Therefore, it is important to model this polycrystalline defect in the crystal growth process and identify key process variables and their features. However, to model the crystal growth process poses great challenges due to complicated engineering mechanisms and a large amount of functional process variables. In this article, we focus on modeling the relationship between a binary quality indicator for polycrystalline defect and functional process variables. We propose a logistic regression model with hierarchical nonnegative garrote-based variable selection method that can accurately estimate the model, identify key process variables, and capture important features. Simulations and a case study are conducted to illustrate the merits of the proposed method in prediction and variable selection.</p
Antifungal activity of phenolic monoterpenes and structure-related compounds against plant pathogenic fungi
<p>The aim of this work is to explore the possibility of using the phenolic monoterpenes (PMs) as leading compounds with antifungal activity against plant disease. The <i>in vitro</i> antifungal activities of carvacrol and thymol against seven kinds of plant pathogenic fungi were evaluated on mycelium growth rate method, and the results showed that carvacrol and thymol exhibited broad spectrum antifungal activity. Structure requirement for the antifungal activity of PMs was also investigated. The preliminary conclusion was that phenolic hydroxyl and monoterpene were basic structures for the antifungal activity of PMs, and the position of phenolic hydroxyl showed less effect. Ester derivatives of carvacrol and thymol were more effective than carvacrol and thymol against plant pathogenic fungi. We suggested that carvacrol, thymol and their ester derivatives could potentially be used as new fungicide leading compounds.</p
Synthesis and antifungal activity of carvacrol and thymol esters with heteroaromatic carboxylic acids
<p>Aiming to obtain the more effective pathogen inhibitive ingredients and explore the influence of introducing different heterocyclic units to carvacrol and thymol esters, twenty ester derivatives with different heterocyclic units were synthesized. And the <i>in vitro</i> antifungal activity of title compounds against five plant pathogenic fungi was evaluated by mycelium growth rate method. The results showed that some carvacrol and thymol esters showed good to excellent antifungal activity, and compound 9d (4-bromo-5-isopropyl-2-methylphenyl picolinate) exhibited a broad antifungal spectrum. Preliminary study indicated that the introduction of furan, thiophene and pyridine unit could enhance the antifungal activity of carvacrol and thymol esters against <i>Botrytis cinerea</i> and a bromine atom on the <i>para</i> position of benzene moiety could enhance their antifungal activity.</p