204 research outputs found
An algorithm for the estimation of the Signal-to-Noise Ratio in surface myoelectric signals generated during cyclic movements
Motion Artifact Reduction in Breast Dynamic Infrared Imaging
Dynamic infrared imaging is a promising technique in breast oncology. In this study a QWIP infrared camera is used to acquire a sequence of consecutive thermal images of the patient's breast for 10 s. Information on the local blood perfusion is obtained from the spectral analysis of the time series at each image pixel. Due to respiratory and motion artifacts, the direct comparison of the temperature values that a pixel assumes along the sequence becomes difficult. In fact, the small temperature changes due to blood perfusion, of the order of 10-50 mK, which constitute the signal of interest in the time domain, are superimposed onto large temperature fluctuations due to the subject's motion, which represent noise. To improve the time series signal-to-noise ratio, and, as a consequence, enhance the specificity and sensitivity of the dynamic infrared examination, it is important to realign the thermal images of the acquisition sequence thus reducing motion artifacts. In a previous study we demonstrated that a registration algorithm based on fiducial points is suitable to both clinical applications and research, when associated with a proper set of skin markers. In this paper, we quantitatively evaluate the performance of different marker sets by means of a model that allows for estimating the signal-to-noise ratio increment due to registration, and we conclude that a 12-marker set is a good compromise between motion artifact reduction and the time required to prepare the patien
Noise estimation in infrared image sequences: a tool for the quantitative evaluation of the effectiveness of registration algorithms
Evaluation of time-series registration methods in dynamic area telethermometry for breast cancer detection
Automated motion reduction in 3D dynamic infrared imaging is on demand in many applications. Few methods for registering time-series dynamic infrared frames have been proposed. Almost all such methods are feature based algorithms requiring manual intervention. We apply different automated registration methods based on spatial displacement to 11 datasets of Breast Dynamic Infrared Imaging (DIRI) and evaluate the results in terms of both the image similarity and anatomical consistency of the transformation. The aim is to optimize the registration strategy for breast DIRI in order to improve the spectral analysis of temperature modulation; thus facilitating the acquisition procedure in a Dynamic Area Telethermometry framework. The results show that symmetric diffeomorphic demons registration outperforms both warped frames similarity and smoothness of deformation fields; hence proving effective for time-series dynamic infrared registratio
Reduction of gait abnormalities in type 2 diabetic patients due to physical activity: a quantitative evaluation based on statistical gait analysis
The aim of this study is the objective assessment of gait abnormalities in diabetic patients and the quantification of the benefits of physical activity in improving the gait quality. Patients were equipped with foot-switches and knee goniometers and were asked to walk at their natural pace for 2.5 minutes. A statistical gait analysis was performed extracting from hundreds of strides the ‘atypical' cycles, i.e. the cycles which do not show the usual sequence of gait phases (heel contact, flat foot contact, push off, swing), the duration of the heel contact phase and the knee kinematics in the sagittal plane. A sample population of 27 non-neuropathic type 2 diabetic patients was examined before and after attending a light-intensity physical activity program that lasted four months. A fuzzy classifier was used to assign a score to the gait abnormalities of each patient in baseline conditions and after the program completion. More than 50% of the subjects reduced significantly their gait abnormalities and, on the average, the most frequent improvements were the reduction of atypical cycles and heel contact duration. Furthermore we found that, in basal conditions, the left side is more affected by gait abnormalities than the right one (P < 0.003
An Algorithm for Choosing the Optimal Number of Muscle Synergies during Walking
In motor control studies, the 90% thresholding of variance accounted for (VAF) is the
classical way of selecting the number of muscle synergies expressed during a motor task. However,
the adoption of an arbitrary cut-off has evident drawbacks. The aim of this work is to describe and
validate an algorithm for choosing the optimal number of muscle synergies (ChoOSyn), which can
overcome the limitations of VAF-based methods. The proposed algorithm is built considering the
following principles: (1) muscle synergies should be highly consistent during the various motor
task epochs (i.e., remaining stable in time), (2) muscle synergies should constitute a base with
low intra-level similarity (i.e., to obtain information-rich synergies, avoiding redundancy). The
algorithm performances were evaluated against traditional approaches (threshold-VAF at 90% and
95%, elbow-VAF and plateau-VAF), using both a simulated dataset and a real dataset of 20 subjects.
The performance evaluation was carried out by analyzing muscle synergies extracted from surface
electromyographic (sEMG) signals collected during walking tasks lasting 5 min. On the simulated
dataset, ChoOSyn showed comparable performances compared to VAF-based methods, while, in
the real dataset, it clearly outperformed the other methods, in terms of the fraction of correct
classifications, mean error (ME), and root mean square error (RMSE). The proposed approach may be
beneficial to standardize the selection of the number of muscle synergies between different research
laboratories, independent of arbitrary thresholds
Evaluation of muscle synergies stability in human locomotion: A comparison between normal and fast walking speed
Motor control strategies can be described by
muscle synergies, a model of functional muscle recruitment to
perform a movement. However, stability of muscle synergies
during locomotion has not yet been investigated. The objective of
this work was the evaluation of the stability of muscle synergies
while walking at normal (NS) and fast (FS) speed. Each walking
condition was tested during a prolonged session lasting 5 minutes
on five healthy subjects. After data processing with statistical gait
analysis, 168±29 valid strides in NS and 181±48 in FS were
obtained. They were aggregated in subgroups, with 10 strides
each. Muscle synergies were extracted for all subgroups with
non-negative matrix factorization. On the average, 6 synergies
were suitable to reconstruct the original electromyographic
signal. They were functionally correlated to the activities of
propulsion, trunk stability, limb deceleration at the end of swing,
forefoot control, and limb stiffening for initial contact stability.
To compare muscle synergy stability over time, a similarity
measurement was carried out. This showed that from 1 to 3
synergies were unstable in NS. As for the FS condition, only one
subject showed unstable synergies, corresponding to the hip
stabilizing synergy
Circular components in center of pressure signals
Static posturography provides an objective assessment of postural control by characterizing the body sway during upright standing. The Center-of-Pressure (CoP) signal is recorded by a force platform and it is analyzed by means of many different models and techniques. Most of the parameters calculated according to these different approaches are affected by relevant intra- and inter-subject variability and/or do not have a clear physiological interpretation. Traditional approaches decompose the CoP signal into antero-posterior and medio-lateral time series, corresponding to ankle plantar/dorsiflexion and hip adduction/abduction, respectively. In this study we hypothesized that CoP signals show inherent rotational characteristics. To verify our hypothesis we applied the rotary spectra analysis to the 2-dimensional CoP signal to decompose it into clockwise and counter-clockwise rotational components. We demonstrated the presence of rotational components in the CoP signal of healthy subjects, providing a reference data set of the spectral characteristics of these component
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