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The Tabby cat locus maps to feline chromosome B1.
The Tabby markings of the domestic cat are unique coat patterns for which no causative candidate gene has been inferred from other mammals. In this study, a genome scan was performed on a large pedigree of cats that segregated for Tabby coat markings, specifically for the Abyssinian (Ta-) and blotched (tbtb) phenotypes. There was linkage between the Tabby locus and eight markers on cat chromosome B1. The most significant linkage was between marker FCA700 and Tabby (Z = 7.56, theta = 0.03). Two additional markers in the region supported linkage, although not with significant LOD scores. Pairwise analysis of the markers supported the published genetic map of the cat, although additional meioses are required to refine the region. The linked markers cover a 17-cM region and flank an evolutionary breakpoint, suggesting that the Tabby gene has a homologue on either human chromosome 4 or 8. Alternatively, Tabby could be a unique locus in cats
A Layer Correlation Technique for ATLAS Calorimetry Calibration at the 2004 ATLAS Combined Beam Test
A method for calibrating the response of a segmented calorimeter to hadrons is developed. The ansatz is that information on longitudinal shower fluctuations gained from a principal component analysis of the layer energy depositions can improve energy resolution by correcting for hadronic invisible energy and dead material losses: projections along the eigenvectors of the correlation matrix are used as input for the calibration. The technique is used to reconstruct the energy of pions impinging on the ATLAS calorimeters during the 2004 Barrel Combined Beam Test at the CERN H8 area. Simulated Monte Carlo events are used to derive corrections for invisible energy lost in nuclear reactions and in dead material in front and in between the calorimeters. For pion beams with energies between 20 and 180 GeV, the particle energy is reconstructed within 3% and the resolution is improved by about 20%
Electrically tunable GHz oscillations in doped GaAs-AlAs superlattices
Tunable oscillatory modes of electric-field domains in doped semiconductor
superlattices are reported. The experimental investigations demonstrate the
realization of tunable, GHz frequencies in GaAs-AlAs superlattices covering the
temperature region from 5 to 300 K. The orgin of the tunable oscillatory modes
is determined using an analytical and a numerical modeling of the dynamics of
domain formation. Three different oscillatory modes are found. Their presence
depends on the actual shape of the drift velocity curve, the doping density,
the boundary condition, and the length of the superlattice. For most bias
regions, the self-sustained oscillations are due to the formation, motion, and
recycling of the domain boundary inside the superlattice. For some biases, the
strengths of the low and high field domain change periodically in time with the
domain boundary being pinned within a few quantum wells. The dependency of the
frequency on the coupling leads to the prediction of a new type of tunable GHz
oscillator based on semiconductor superlattices.Comment: Tex file (20 pages) and 16 postscript figure
Quasiperiodic time dependent current in driven superlattices: distorted Poincare maps and strange attractors
Intriguing routes to chaos have been experimentally observed in semiconductor
superlattices driven by an ac field. In this work, a theoretical model of time
dependent transport in ac driven superlattices is numerically solved. In
agreement with experiments, distorted Poincare maps in the quasiperiodic regime
are found. They indicate the appearance of very complex attractors and routes
to chaos as the amplitude of the AC signal increases. Distorted maps are caused
by the discrete well-to-well jump motion of a domain wall during spiky
high-frequency self-sustained oscillations of the current.Comment: 10 pages, 4 figure
The role of prestimulus activity in visual extinction.
Patients with visual extinction following right-hemisphere damage sometimes see and sometimes miss stimuli in the left visual field, particularly when stimuli are presented simultaneously to both visual fields. Awareness of left visual field stimuli is associated with increased activity in bilateral parietal and frontal cortex. However, it is unknown why patients see or miss these stimuli. Previous neuroimaging studies in healthy adults show that prestimulus activity biases perceptual decisions, and biases in visual perception can be attributed to fluctuations in prestimulus activity in task relevant brain regions. Here, we used functional MRI to investigate whether prestimulus activity affected perception in the context of visual extinction following stroke. We measured prestimulus activity in stimulus-responsive cortical areas during an extinction paradigm in a patient with unilateral right parietal damage and visual extinction. This allowed us to compare prestimulus activity on physically identical bilateral trials that either did or did not lead to visual extinction. We found significantly increased activity prior to stimulus presentation in two areas that were also activated by visual stimulation: the left calcarine sulcus and right occipital inferior cortex. Using dynamic causal modelling (DCM) we found that both these differences in prestimulus activity and stimulus evoked responses could be explained by enhanced effective connectivity within and between visual areas, prior to stimulus presentation. Thus, we provide evidence for the idea that differences in ongoing neural activity in visually responsive areas prior to stimulus onset affect awareness in visual extinction, and that these differences are mediated by fluctuations in extrinsic and intrinsic connectivity
Measurement of miniband parameters of a doped superlattice by photoluminescence in high magnetic fields
We have studied a 50/50\AA superlattice of GaAs/AlGaAs
composition, modulation-doped with Si, to produce
cm electrons per superlattice period. The modulation-doping was tailored
to avoid the formation of Tamm states, and photoluminescence due to interband
transitions from extended superlattice states was detected. By studying the
effects of a quantizing magnetic field on the superlattice photoluminescence,
the miniband energy width, the reduced effective mass of the electron-hole
pair, and the band gap renormalization could be deduced.Comment: minor typing errors (minus sign in eq. (5)
Absence of quantum-confined Stark effect in GaN quantum disks embedded in (Al,Ga)N nanowires grown by molecular beam epitaxy
Several of the key issues of planar (Al,Ga)N-based deep-ultraviolet light
emitting diodes could potentially be overcome by utilizing nanowire
heterostructures, exhibiting high structural perfection and improved light
extraction. Here, we study the spontaneous emission of GaN/(Al,Ga)N nanowire
ensembles grown on Si(111) by plasma-assisted molecular beam epitaxy. The
nanowires contain single GaN quantum disks embedded in long (Al,Ga)N nanowire
segments essential for efficient light extraction. These quantum disks are
found to exhibit intense emission at unexpectedly high energies, namely,
significantly above the GaN bandgap, and almost independent of the disk
thickness. An in-depth investigation of the actual structure and composition of
the nanowires reveals a spontaneously formed Al gradient both along and across
the nanowire, resulting in a complex core/shell structure with an Al deficient
core and an Al rich shell with continuously varying Al content along the entire
length of the (Al,Ga)N segment. This compositional change along the nanowire
growth axis induces a polarization doping of the shell that results in a
degenerate electron gas in the disk, thus screening the built-in electric
fields. The high carrier density not only results in the unexpectedly high
transition energies, but also in radiative lifetimes depending only weakly on
temperature, leading to a comparatively high internal quantum efficiency of the
GaN quantum disks up to room temperature.Comment: This document is the unedited Author's version of a Submitted Work
that was subsequently accepted for publication in Nano Letters (2019),
copyright (C) American Chemical Society after peer review. To access the
final edited and published work see
https://doi.org/10.1021/acs.nanolett.9b01521, the supporting information is
available (free of charge) under the same lin
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