Individual Development of Professionalism in Educational Peer Group Supervision: A Multiple Case Study of GPs

Background. Research has shown that peer-group supervision can strengthen GPs’ professionalism, but little is known about the individual learning processes. To establish professionalism beyond professional behaviour, identity and idealism need to be included. The inner attitudinal values of professionalism within the individual are, however, difficult to assess. Aim. On the basis of a multiple case study, this paper describes the process of professional learning and challenges for individual GPs, as they take part in supervision groups focusing on children cases. Methods and Results. By using a two-dimensional theoretical model, it is shown that all GPs developed their professional behaviour, and many of them strengthened their professional identity in this domain towards a changed professionalism. Most participants emphasized the positive experience of sharing worries with families indicating care and interest. Some participants learning processes were very linear/convergent; others were complex/divergent—starting out with a relatively simple objective, realizing how multifaceted the issue was after the first year leading to a final development of new perspectives or action possibilities. Conclusion. The composition of supervision groups, as well as the professional background of the supervisor, may play a significant role in the development of professional behaviour and professionalism.Peer Reviewe

Ag–ZnO Nanocomposites as a 3D Metal-Enhanced Fluorescence Substrate for the Fluorescence Detection of DNA

Fluorescence enhancement, including metal-enhanced fluorescence (MEF), has been widely explored in the field of biosensor technology. Two- and three-dimensional (2D and 3D) MEF substrate approaches have been developed for biosensors to detect target biomarkers such as genes and proteins. However, several issues remain, not least poor reproducibility caused by limited recognition and diffusion of biomolecules among target molecules, biological probes, and MEF substrates in aqueous environments. Here, an Ag–ZnO nanocomplex as a 3D MEF substrate was developed in two steps: hydrothermal synthesis of ZnO nanowire (NW) as a building block of Ag nanoparticles (NPs), and photochemical deposition of AgNPs on the ZnO NW. Fluorescence enhancement on Ag–ZnO nanocomposites (NCs) compared with the glass substrate was 14.8-, 16.9-, 11.4-, and 14.2-fold in the presence of 10, 20, 40, and 60 base pair (bp) double-stranded (ds) DNA, respectively. The MEF effects on glass, ZnO NW, and Ag–ZnO NCs were analyzed by measuring the fluorescence lifetime of fluorescein (FAM)-labeled dsDNA, and the average lifetimes were 9.76, 9.34, and 7.86 ns, respectively. Ag–ZnO NCs showed a 50-fold higher sensitivity for the detection of dsDNA than Ag nanoisland film (AgNIF) as a 2D MEF substrate. Therefore, Ag–ZnO NCs may have potential as a 3D MEF substrate. The MEF phenomenon might involve broad-range interactions between the surface of the metal nanostructure on Ag–ZnO NCs and fluorophores in various scenarios. Our Ag–ZnO NCs could facilitate the development of sensitive MEF-based biosensors for DNA detection

Additional file 1: of Nodding behavior couples to vigilance fluctuation in a high-calorie diet model of drowsiness

Figure S1. Behavioral measurement according to vigilance level. Comparison of head/eye condition according to the behavior patterns. (PDF 92 kb

Additional file 2: of Nodding behavior couples to vigilance fluctuation in a high-calorie diet model of drowsiness

Figure S2. Analysis of HF effects on drowsy states including nodding behavior. (a) The average length of nodding episode in the no-food and high-fat food groups (unpaired t-test, p = 0.887, no food n = 2 and high-fat n = 4, n.s. indicates ‘not significant’). All error bars represent s.e.m. (b) The mean duration of no food and high-fat food groups during Nd (unpaired t-test, p = 0.886) and Non-Nd states (unpaired t-test p = 0.895, no food n = 2 and high-fat n = 4). All error bars represent s.e.m. (PDF 88 kb

Electric Field Effects on Internal Conversion: An Alternative Mechanism for Field-Induced Fluorescence Quenching of MEH-PPV and Its Oligomers in the Low Concentration Limit

In a previously published study (J. Phys. Chem. B 2006, 110, 7732−7742), we reported field-induced fluorescence quenching in both poly[2-methoxy,5-(2‘-ethylhexyloxy)-1,4-phenylene vinylene] (MEH-PPV) and several model oligomers in solvent glass matrices at high dilution (<0.1% by weight). The observed quenching is not readily explained by field-induced exciton dissociation or by the presence of free charges, two mechanisms that have been invoked to explain this phenomenon by previous authors. A model is developed here that ascribes the observed fluorescence quench in dilute samples to an energetic shift of the relaxed excited state caused by the electric field resulting in increased nonradiative relaxation. To determine whether the relevant nonradiative pathway is intersystem crossing or internal conversion, analytical expressions are derived for each of these two mechanisms. Only the expression derived for the Stark effect on the rate of internal conversion quantitatively predicts the magnitude of quench observed in MEH-PPV and in the oligomeric species

MOESM3 of A systematic review reporting quality of radiomics research in neuro-oncology: toward clinical utility and quality improvement using high-dimensional imaging features

Additional file 3: Table S2. Characteristics of the included studies

Additional file 1: Figure S1. of Fabrication of Uniform Nanoporous Oxide Layers on Long Cylindrical Zircaloy Tubes by Anodization Using Multi-Counter Electrodes

Tubular-shaped Pt cathode with a lot of small holes and an anodization system using the cathode. Figure S2. a) Oxide thickness distribution and b) electric field distribution according to the angular position of the Zr-Nb-Sn tube. The tube anodized in the one-, two-, three-, and four-wire system are marked as black, red, purple, and blue lines, respectively. (DOC 408 kb

MOESM1 of A systematic review reporting quality of radiomics research in neuro-oncology: toward clinical utility and quality improvement using high-dimensional imaging features

Additional file 1: Table S1. The six key domains of the radiomics quality score

MOESM2 of A systematic review reporting quality of radiomics research in neuro-oncology: toward clinical utility and quality improvement using high-dimensional imaging features

Additional file 2: Figure S1. RQS score according to the journal shows no definite systematic differences between the journals

Additional file 3: Table S3. of Whole genome sequence analysis of the TALLYHO/Jng mouse

Classification of TH indels by sets of SO terms associated with the indel. (XLSX 10 kb