Canine seropositivity rates to <i>Orientia</i>–specific antigens in study cites on Chiloé Island and in previous studies from Asia.

<p>Canine seropositivity rates to <i>Orientia</i>–specific antigens in study cites on Chiloé Island and in previous studies from Asia.</p

Geographical distribution of seropositive and -negative dogs and location of grouped cases by LISA analysis on Chiloé Island (Open source maps from Albers C. (2012): Coberturas SIG para la enseñanza de la Geografía en Chile.

<p>Universidad de La Frontera. Temuco. Available at: <a href="http://www.rulamahue.cl/mapoteca" target="_blank">www.rulamahue.cl/mapoteca</a>.</p

Univariable Generalized Lineal Model with binomial error indicating the factors associated with <i>Orientia</i> seropositivity in dogs (n = 202) on Chiloé Island.

<p>Univariable Generalized Lineal Model with binomial error indicating the factors associated with <i>Orientia</i> seropositivity in dogs (n = 202) on Chiloé Island.</p

Serum levels of circulating soluble VCAM-1.

<p>Dot plots demonstratesVCAM-1 levels in inoculated mouse sera. (Mock inoculation; n = 2 per time point, <i>O. tsutsugamushi</i> inoculation; n = 6 per time point). Bars indicate median and error bars represent interquartile range. The asterisks indicate significant differences (<i>P</i><0.05).</p

Summary of qPCR and sequencing results for mosquito samples obtained from the Republic of Korea.

<p>Summary of qPCR and sequencing results for mosquito samples obtained from the Republic of Korea.</p

Percent sequence identity of the mosquito genotypes to <i>Rickettsia</i> species with validly published names and other mosquito rickettsial strains provided in the GenBank.

<p>Percent sequence identity of the mosquito genotypes to <i>Rickettsia</i> species with validly published names and other mosquito rickettsial strains provided in the GenBank.</p

Polygala stipulacea

<p>Dot plots demonstrates ICAM-1 levels in inoculated mouse sera. (Mock inoculation; n = 2 per time point, <i>O. tsutsugamushi</i> inoculation; n = 6 per time point). Bars indicate median and error bars represent interquartile range. The asterisks indicate significant differences (<i>P</i><0.05).</p

A dendrogram showing the phylogenetic position of <i>Rickettsia</i> sp. A12.2646 from <i>Mn</i>. <i>uniformis</i>, <i>Rickettsia</i>. sp. A12.2638 from <i>Cx</i>. <i>pipiens</i> and A12.3271 from <i>Ae</i>. <i>esoensis</i> from the Republic of Korea in relation to other <i>Rickettsia</i> species with validly published names for the <i>gltA</i> gene (993-bp).

<p>The evolutionary history was inferred by the maximum likelihood method.</p

Map of the northern part of Gyeonggi province denoting collection sites of mosquitoes at NNSC (Neutral Nations Supervisory Commission camp adjacent to the Panmunjeom), Daeseongdong (located inside the Demilitarized Zone), Warrior Base (US Army training site) and Tongilchon (beef farm) located 2 km and 3 km, respectively from the MDL southern boundary of the Demilitarized Zone.

<p>Map of the northern part of Gyeonggi province denoting collection sites of mosquitoes at NNSC (Neutral Nations Supervisory Commission camp adjacent to the Panmunjeom), Daeseongdong (located inside the Demilitarized Zone), Warrior Base (US Army training site) and Tongilchon (beef farm) located 2 km and 3 km, respectively from the MDL southern boundary of the Demilitarized Zone.</p

Macroscopic evidence of regional lymphadenopathy in <i>O. tsutsugamushi</i> inoculated mice.

<p>Gross examination of draining lymph nodes (right superficial parotid lymph node) from <i>O. tsutsugamushi</i> inoculated mice at day 3 pi (left) and day 7 pi (right) shows enlargement of lymph nodes at day 7. Top panel: Karp-inoculated mice, Middle panel: Gilliam-inoculated mice, Bottom panel: Woods-inoculated mice.</p