Complete Search Strategy for Medline/PubMed.

<p>Complete Search Strategy for Medline/PubMed.</p

Conclusions of the included RCTs as a function of risk of selection bias.

<p>Conclusions of the included RCTs as a function of risk of selection bias.</p

Results of the literature search.

<p>Results of the literature search.</p

Associations of year of publication (post-CONSORT vs. pre-CONSORT) and impact factor (with impact factor vs. without) with risk of selection bias.

<p>B, regression coefficient; CI, confidence interval; OR, odds ratio; SE, standard error.</p

Associations of risk of selection bias and impact factor in randomized controlled trials of yoga.

<p>Associations of risk of selection bias and impact factor in randomized controlled trials of yoga.</p

Associations of risk of selection bias and publication year in randomized controlled trials of yoga.

<p>Associations of risk of selection bias and publication year in randomized controlled trials of yoga.</p

Effect sizes for the primary outcomes quality of life, fatigue, and mobility.

<p>*both exercise groups combined; **means and standard deviations provided upon request.</p

Sensitivity analysis: effect sizes when only trials with low risk of detection bias were included.

<p>Sensitivity analysis: effect sizes when only trials with low risk of detection bias were included.</p

Effect sizes for the secondary outcomes mood and cognitive function.

<p>*standard deviation imputed from other studies; **means and standard deviations provided upon request.</p

Characteristics of the included studies.

<p>Abbreviations: BAI – Beck Anxiety Inventory; BDI – Beck Depression Inventory; CES-D - Center for Epidemiological Studies Depression Scale; d2CP – Brickenkamp d2 test concentration performance; FSS – Fatigue Severity Scale; MAS – Modified Ashworth Scale; MFI – Multidimensional Fatigue Inventory; MFIS – Modified Fatigue Impact Scale; MS – multiple sclerosis; MSIS-29v2– Multiple Sclerosis Impact Scale-29, version2; MSQOL54 - Multiple Sclerosis Quality of Life 54; NA – Not assessed; NAB – Neuropsychological Assessment Battery; NR – not reported; NS – not significant; PASAT – Paced Auditory Serial Addition Test; POMS – Profile of Mood States; SF-36 - Short Form-36 Health Survey; SSS – Stanford Sleepiness Scale; STAI – State Trait Anxiety Inventory; TOL – Tower of London Test.</p><p>Characteristics of the included studies.</p