Microbiological Assessment of Commercial Yogurt Sold in Ota Metropolis, Ogun State, Nigeria

Ten authorized Yogurt products purchased within Ota metropolis, Ogun State of Nigeria were subjected to pH, Total Bacterial Count (TBC) and Total Fungal Count (TFC) analysis. pH values were in the range of 4.05 to 5.50, the TBC and TFC values ranged between 1.0 x 103 - 5.0 x 105 cfu/ml and 1.0 x 103- 5.0 x 105 cfu/ml respectively. Eleven bacterial isolates were detected in the yogurt samples. Lactobacillus spp. and Bacillus spp. constituted 16% of the total microbial load, Corynebacterium spp., Klebsiela spp., Staphylococcus spp., and Pseudomonas spp. constituted 8% while Proteus spp., Micrococcus spp., Shigella spp., Listeria spp., and Streptococcus spp. constituted 4%. Fungal isolates obtained were Mucor spp. (22%), Geotrichum spp. (17%), Montospora spp. (11%), while Aspergillus spp., Rhizopus spp., and Fusanrium spp. constituted 6%.The antimicrobial susceptibility test showed that the isolates exhibited susceptible to Ciprofloxacin and Ofloxacin and resisted Nitrofurantoin, Augumentin, Cefixime, Ceufuroxime, Gentamicin and Ceftazidime. The isolates were plasmid encoded, with size range of 20,000- 40,000 Kilo base pairs. Result show no significant difference within the bacteria isolates (P> 0.05), while the fungi isolates showed significant difference (P<0.05). Significant difference also occurred between the bacteria and the fungi isolate (P< 0.05)

Occupational Wellness and its Determinants among Cocoa Farmers in South-West Nigeria

Occupational wellness is essential for cocoa farmers’ health and productivity since a significant proportion of their time is spent at work. It is a measure of individual wellbeing, focusing on the psychosocial status as it relates to individuals’ profession. This study assessed occupational wellness and its determinants among cocoa farmers in the South-West region of Nigeria. A descriptive cross-sectional study design was used to study 244 cocoa farmers in Ekiti and Osun States. Also, the local government areas were purposively selected as being well known for cocoa production. A semi-structured interviewer-administered questionnaire was used to obtain data on sociodemographic characteristics and occupational wellness. Occupational wellness was scored based on their response to eight sets of questions with a 4-point Likert scale response. Association between the farmers’ characteristics and occupational wellness was assessed using Mann Whitney U and Kruskal Wallis tests. Determinants of occupational wellness were assessed using quantile regression. The median occupational wellness score was 25.0 (IQR = 24.0 – 29.0). People of low educational status had higher occupational wellness scores, p &lt; 0.001. Significant associations were also observed between other characteristics like sex, religion, marital status, geographical location, farm ownership, and occupational wellness. Farm ownership was also a significant determinant of occupational wellness. The occupational wellness status is due to a complex mix of occupational factors, sociodemographic factors, and geographic factors. Health promotion will be key in maintaining a balance of the mix to enhance the general wellbeing and productivity of the farmers.</jats:p

Understanding the gaps in DR-TB care cascade in Nigeria: A sequential mixed-method study

Background: Despite the availability of free drug-resistant tuberculosis (DR-TB) care in Nigeria since 2011, the country continues to tackle low case notification and treatment rates. In 2018, 11% of an estimated 21,000 cases were diagnosed and 9% placed on treatment. These low rates are nevertheless a marked improvement from 2015 when only 3.4% were diagnosed and 2.3% placed on treatment of an estimated 29,000 cases. This study describes the Nigerian DR-TB care cascade from 2013 to 2017 and considers factors influencing gaps in care. Methods: Our study utilized a mixed-method design. For the quantitative component, we utilized the national diagnosis and treatment databases, as well as the World Health Organization's estimates for prevalence to construct a 5-year care cascade: numbers of patients at each level of DR-TB care, including incident cases, individuals who accessed testing, were diagnosed, initiated treated and completed treatment in Nigeria between 2013 and 2017. Using retrospective data for patients diagnosed in 2015, we performed the Fisher's exact test to determine the association between patient (age and gender) and provider/patient (region- north or south) variables, permitting a closer look at the gaps in care revealed across the 5 years. Barriers to care were explored using framework thematic analysis of 57 qualitative interviews and focus group discussions with patients, including 5 cases not initiated on treatment from the 2015 cohort, treatment supporters, community members, healthcare workers and program managers in 2017. Results: A 5-year analysis of cascade of care data shows significant, but inadequate, increases in overall numbers of cases accessing care. On average, between 2013 and 2017, 80% of estimated cases did not access testing; 75% of those who tested were not diagnosed; 36% of those diagnosed were not initiated on treatment and 23% of these did not finish treatment. In 2015, children and patients in Northern Nigeria had odds of 0.3 [95% CI 0.1–0.7] and 0.4 [0.3–0.5] of completing treatment once diagnosed; while males were shown to have a 1.34 [95% CI 1.0–1.7] times greater chance of completing treatment after diagnosis

Rates and timeliness of treatment initiation among drug-resistant tuberculosis patients in Nigeria- A retrospective cohort study.

BackgroundThere were an estimated 580,000 new cases of multidrug/rifampicin resistant TB (DR-TB) in 2015, and only 20% were initiated on treatment. This study explored health system and patient factors associated with initiation and timeliness of treatment among DR-TB patients in Nigeria, ranked 4th globally for estimated TB cases in 2015.MethodsA retrospective cohort study using 2015 diagnosis and treatment data from the Nigerian TB program electronic records examined "treatment ever received" (yes/no) and "treatment within 30 days" (yes/no). We compared health system and patient characteristics using binomial logistic regression, while controlling for confounders.ResultsOf 996 patients diagnosed nationwide in 2015 (aged 0-87 years, median 34), 47.8% were never treated. Of those treated (n = 520), 51.2% were treated within the 30 days prescribed in the National treatment guideline. Healthcare facility locations were significantly associated with ever receiving treatment and timely treatment. Predictors of timely treatment at the national level also included level of care and patient treatment history. The South-West zone, where DR-TB programs started, showed overall better access to DR-TB healthcare.ConclusionsHealthcare facility geographic locations were significantly associated with treatment initiation and timeliness. Significant regional differences in access to DR-TB care in Nigeria persist, reflecting uneven contexts for national DR-TB treatment rollout

Time-to-treatment initiation in the Geopolitical zones, adjusted for sex, age and urban/rural.

Time-to-treatment initiation in the Geopolitical zones, adjusted for sex, age and urban/rural.</p

National and regional characteristics and predictors of treatment within 30 days amongst DR-TB diagnosed patients in 2015.

National and regional characteristics and predictors of treatment within 30 days amongst DR-TB diagnosed patients in 2015.</p

Description of basic characteristics of study and excluded population.

Description of basic characteristics of study and excluded population.</p