第831回千葉医学会例会・第15回千葉大学放射線医学教室例会

Figure S2. All a-DMRs within (1) genomic location. Top: a-DMRs (purple), gene, DHS clusters, transcription factor ChIP-seq, ChromHMM segmentation, combined segmentation and conservation; and (2) scatterplot: x-axis = Age, y-axis = Normalised methylation. (PDF 34909 kb

A Historicai Consideration on the Changes of the Wabicha (Tea Ceremony) and the Roji (Tea Garden) : Part 3: The Succession and development of Oribe\u27s Style for Tea Ceremony by Enshu

織部において, 茶室, 茶庭は客のためのよりよき茶を演出するための場としてとらえる立場をとる.この織部の茶を継承し, さらに展開した遠州は茶庭(露地)のための造形を含めて, かずかずの茶の造形をものしている.しかも, その中には, 後世に受けつがれ, 語りつがれる, すぐれた数々の成果がある.このすぐれた成果を生み出した基盤には, 彼の豊かな天賦の才があったこと勿論であるが, しかし, 一方, 彼を取り巻くすぐれた人びとが, 彼のこのすぐれた天賦の才をさらにみがき, そして大きく育てる役割を果したことも, また軽視できないといわねばならない.本報告では, このような遠州を取り巻くすぐれた人びとの中で, 特に松花堂昭乗を取りあげる.滝本坊客殿の幅広い東縁と, これから茶室・閑雲軒の躙口へ通じる狭い榑縁と, このひとつらなりの廊下がつくり出す構成は, 外露地から内露地への園路の構成に通じるものといえる.而して, この構成を, 遠州が先きに金地院八窓席の躙口まえにおいて試みた手法から, さらに一歩を踏み出したデザインとみる.また, その手水構えにおいても, ここ閑雲軒においては, 蹲踞構えではなく, 書院における縁先手水の構えを思わせる構成をとるものであって, それは廊下を園路と見立てる手法によって, はじめて成立する構成といえる.そして, この構成は, やがて, 書院茶室へと展開する遠州の新しい茶の造形に向う, 一階梯として大きな意義をもつ.また, 滝本坊茶立所の室内構成をみるとき, そこには遠州伏見屋敷におけるデザインからの発展といえるかずかずの特徴がみられる.さらに, この滝本坊茶立所における作事のかずかずの体験が, やがて, 遠州の造形デザインの世界を, さEnshu Kobori succeeded Oribe Furuta\u27s style for a wabicha (a tea ceremony in the special room or house for it) to recieve the quests with a tea in the hospitable settings of a room and a garden, and developed it cultivating his talent by the communicaion with several outstanding people of his salon like Shojo Shokado or a monk of Iwashimizu Hachimangu. One of the process of the development could be found in the approach from the kyakuden (a reception hall) of Takimotobo of Shojo\u27s living house to Kanunken of a special house for a tea ceremony through the verandah, and in the design of chatatedokoro, i.e. the room for a wabicha in a shoin style. The way from the kyakuden to Kanunken through the verandah would have been supposed as the way from a soto-roji to a uchi-roji, and a set of tsukubai or a basin for washing hands beside the verandah used like a ensaki-chouzu in case of a shoincha or a tea service in a shoin. And, we can point out several effects of Shojo in the design of chatatedokoro. Therefore, the design of Takimotobo is on the way to a wabicha in a shoin style, which is completed by Enshu in the design of Bosen of Kohoan, Daitokuji

Additional file 17: Figure S9. of ABO antigen and secretor statuses are not associated with gut microbiota composition in 1,500 twins

Analyses using only individuals with BMI < 25 recapitulate results. A-C) Neither ABO or secretor status associated with broad compositional differences of the gut microbiota in the TwinsUK. None of the top 100 principal coordinates (PCs) from principal coordinate analysis of unweighted UniFrac distance are significantly associated with either ABO or secretor status. The first two PCs are shown, colored by ABO status (A) and secretor status (B). (C) Discriminant analysis of PCA (DAPC) is largely unsuccessful at predicting ABO or secretor status from microbiome data. The mean accuracy from 5-fold cross validation is plotted for ABO status, secretor status, and ABO status only in secreting individuals (yellow). Significance was determined by comparing the accuracy of each test to the accuracies of permuted data, which took into account twin relationships (gray). D-F) Microbiome diversity does not significantly differ by ABO, but does by secretor status. Within sample diversity (Faith’s phylogenic diversity) is significantly different between secretors versus non-secretors (D, P < 0.05), but not across the ABO groups in all individuals (E, P > 0.05), or across ABO groups in only secreting individuals (C, P > 0.05). (F) Microbiomes are more similar for siblings versus pairs of unrelated individuals, as measured by unweighted UniFrac distance. However, microbiomes of pairs of individuals concordant for either ABO or secretor status are not more similar than for pairs of individuals who are discordant. This holds true when all individuals in the dataset are considered (“all individuals”) or when only one individual from each twin pair is examined (“one twin per family”). The total number of pairs of individuals within each boxplot is indicated with “n = “. H) None of the common taxa are associated with ABO or secretor status. QQ-plot displaying the expected –log10(P-value) compared to the –log10(P-value) for all taxa tested in linear mixed models 6 (light gray points) and 8 (dark gray points, as plotting in Fig. 3). Significance codes: P ≤ 0.05 = *, P ≤ 0.01 = **, P ≤ 0.001 = ***, P ≤ 0.0001 = ****, not significant = NS. (PDF 387 kb

NOLAS

Two person exhibition: Laura White and Jessica Flood-Paddock. Collaborative work

Additional file 17: Figure S9. of ABO antigen and secretor statuses are not associated with gut microbiota composition in 1,500 twins

Analyses using only individuals with BMI  0.05), or across ABO groups in only secreting individuals (C, P > 0.05). (F) Microbiomes are more similar for siblings versus pairs of unrelated individuals, as measured by unweighted UniFrac distance. However, microbiomes of pairs of individuals concordant for either ABO or secretor status are not more similar than for pairs of individuals who are discordant. This holds true when all individuals in the dataset are considered (“all individuals”) or when only one individual from each twin pair is examined (“one twin per family”). The total number of pairs of individuals within each boxplot is indicated with “n = “. H) None of the common taxa are associated with ABO or secretor status. QQ-plot displaying the expected –log10(P-value) compared to the –log10(P-value) for all taxa tested in linear mixed models 6 (light gray points) and 8 (dark gray points, as plotting in Fig. 3). Significance codes: P ≤ 0.05 = *, P ≤ 0.01 = **, P ≤ 0.001 = ***, P ≤ 0.0001 = ****, not significant = NS. (PDF 387 kb

Using Rough logic for predicting price movements on financial markets

Financial markets and especially their movements are very difficult to predict. For this reason, it cannot be clearly concluded what market will do. We cannot use basic logical operators such as if A happens, then comes B. Since we cannot use simple decision rules and we work in high uncertainty we cannot easily build classical mathematical model because of uncertainty of each and every result. However to analyze this type of data we can used Rough logic which is design to work with uncertainty. The aim of this thesis is use of Rough logic to create a mathematical model, which will be able to some extent to understand and eventually predict individual market movements. Market uncertainty Purpose of the article: Using Rough logic for predicting price movements. Scientific aim: Rough Set. Conclusions: Methodology for using Rough set in financial markets

Socioeconomic position in early life and epigenetics.

(Organised by exposure, DNA methylation (epigenome wide, global methylation, imprinted genes, other genes).</p

Nutrition in early life and epigenetics.

*(Organised by, exposure, DNA methylation (epigenome wide, global methylation, imprinted genes, other genes).</p

PRISMA Flow diagram of study selection.

*Other includes: reviews, not peer reviewed, publication not found, randomised control trials, animal studies **N’s including overlapping studies (n = 17).</p

Body size in early life and epigenetics.

*(Organised by study design, exposure, DNA methylation (epigenome wide, global methylation, imprinted genes, other genes).</p