Selected results on Strong and Coulomb-induced correlations from the STAR experiment

Using recent high-statistics STAR data from Au+Au and Cu+Cu collisions at full RHIC energy I discuss strong and Coulomb-induced final state interaction effects on identical ($\pi-\pi$) and non-identical ($\pi-\Xi$) particle correlations. Analysis of $\pi-\Xi$ correlations reveals the strong and Coulomb-induced FSI effects allowing for the first time to estimate space extension of $\pi$ and $\Xi$ sources and average shift between them. Source imaging technique providing clean separation of these effects from effects due to the source function itself is applied to one-dimensional relative momentum correlation function of identical pions. For low momentum pions and/or non-central collisions large departure from a single-Gaussian shape is observed

Recent results of the STAR high-energy polarized proton-proton program at RHIC at BNL

The STAR experiment at the Relativistic Heavy-Ion Collider (RHIC) at Brookhaven National Laboratory (BNL) is carrying out a spin physics program colliding transverse or longitudinal polarized proton beams at $\sqrt{s}=200-500$GeV to gain a deeper insight into the spin structure and dynamics of the proton. These studies provide fundamental tests of Quantum Chromodynamics (QCD). One of the main objectives of the STAR spin physics program is the determination of the polarized gluon distribution function through a measurement of the longitudinal double-spin asymmetry, $A_{LL}$, for various processes. Recent results will be shown on the measurement of $A_{LL}$ for inclusive jet production, neutral pion production and charged pion production at $\sqrt{s}=200$GeV. In addition to these measurements involving longitudinal polarized proton beams, the STAR collaboration has performed several important measurements employing transverse polarized proton beams. New results on the measurement of the transverse single-spin asymmetry, $A_{N}$, for forward neutral pion production and the first measurement of $A_{N}$ for mid-rapidity di-jet production will be discussed.Comment: 8 pages, 5 figures, Invited talk given at the 17th International Spin Physics Symposium (SPIN 2006), October 2006, Kyoto, Japa

Longitudinal Spin Asymmetry and Cross Section of Inclusive pi0 Production in Polarized p+p Collisions at RHIC

We present the first measurement of the cross section and the double longitudinal spin asymmetry of inclusive pi0 production in polarized p+p collisions at Sqrt(s) = 200 GeV at mid-rapidity with the STAR detector, using the barrel electromagnetic calorimeter. The measured cross section is compared to NLO pQCD calculations and can provide constraints on the pion fragmentation functions. Fragmentation is studied directly by measuring the momentum fraction of pi0 in jets, a quantity that is affected by the fragmentation process and jet reconstruction effects. The double longitudinal spin asymmetry is compared to NLO pQCD calculations based on different assumptions for the gluon polarization in the nucleon to provide constraints on delta g/g. At the present level of statistics the measured asymmetry disfavors a large positive gluon polarization, but can not yet distinguish between other scenarios.Comment: 4 pages, 2 figures, submitted to the proceedings of the 17th International Spin Physics Symposium (SPIN2006), Kyoto, Japan, October 2 to 7, 200

Measurements of Transverse Spin Effects with the Forward Pion Detector of STAR

Measurements by the STAR collaboration of neutral pion production at large Feynman x (x_F) in the first polarized proton collisions at $\sqrt{s}=200$ GeV were reported previously. Cross sections measured at $\eta=3.3$, 3.8 and 4.0 are found to be consistent with next-to-leading order perturbative QCD calculations. The analyzing power is consistent with zero at negative x_F and at positive x_F up to ~0.3, then grows more positive with increasing x_F. This behavior can be described by phenomenological models including the Sivers effect, the Collins effect or higher twist contributions in the initial and final states. Forward calorimetry at STAR has been extended, and there are plans for further expansion. An integrated luminosity of 6.8 pb^${-1}$ with average beam polarization of 60% from online polarimetry measurements was sampled with the upgraded FPD in the 2006 RHIC run. This data sample will allow for a detailed map of the \pi^0 analyzing power over kinematic variables bounded by 0.3 < x_F < 0.6 and 1.2 < p_T < 5.0 GeV/c at $\sqrt{s}=200$ GeV. The expanded FPD has observed multi-photon final states expected to have "jet-like" characteristics. The transverse spin dependence of jet-like events can discriminate between the Collins and Sivers effects and lead to further progress in understanding the origin of single spin asymmetries in forward particle production. Data were also obtained at $\sqrt{s}=62.4$ GeV for x_F -> 1 to test predictions based on phenomenological fits to earlier STAR results. Recent results, the status of the analysis of 2006 run data and near-term plans will be discussed.Comment: 4 pages, 3 figures, to be published in the proceedings of the 17th International Spin Physics Symposium (SPIN2006), October 2-7, 2006, Kyoto, Japa

Measurement of Sivers Asymmetries for Di-jets in \sqrt{s}=200 GeV pp Collisions at STAR

Measurement of the transverse spin dependence of the di-jet opening angle in pp collisions at sqrt{s}=200 GeV has been performed by the STAR collaboration. An analyzing power consistent with zero has been observed over a broad range in pseudorapidity sum of the two jets with respect to the polarized beam direction. A non-zero (Sivers) correlation between transverse momentum direction of partons in the initial state and transverse spin orientation of the parent proton has been previously observed in semi-inclusive deep inelastic scattering (SIDIS). The present measurements are much smaller than deduced from predictions made for STAR di-jets based on non-zero quark Sivers functions deduced from SIDIS, and furthermore indicate that gluon Sivers asymmetries are comparably small.Comment: 4 pages, 3 figures, talk presented at SPIN 2006, Kyoto, October 200

Association of Symptomatic Human Infection with Toxoplasma gondii with Imbalance of Monocytes and Antigen-Specific T Cell Subsets

During recent symptomatic toxoplasmosis, alterations in quantity and function of mononuclear cellsin peripheral blood were observed. Flow cytofluorometric analysis and differential leukocyte counts revealed increasedabsolute numbers of T8 + cells, Leu 7 + (natural killer/killer) cells, and monocytes. T4+ cells and HLA-DR+ cells were not significantly changed. T4/T8 cell ratios were reversed in symptomatic toxoplasmosis (0.7 ± 0.3) and normal in chronic infection (1.7 ± 0.5). Toxoplasma antigen induced higher numbers of T8 + and TQ1 + cells in four T cell lines from two individuals with symptomatic infection than in five T cell lines from three individuals with asymptomatic infection. Eight cloned T cell lines produced γ interferon in an antigen-specific fashion and in higher amounts when they originated from an asymptomatic subject than from a symptomatic subject. These results indicate that marked alterations in properties of immunoregulatory cells are characteristic of recent symptomatic toxoplasmosis. The transient immune dysfunction may be a major part of the observed disease and/or a feature of successful parasitis

Diverse CD81 proteins support hepatitis C virus infection.

Hepatitis C virus (HCV) entry is dependent on CD81. To investigate whether the CD81 sequence is a determinant of HCV host range, we expressed a panel of diverse CD81 proteins and tested their ability to interact with HCV. CD81 large extracellular loop (LEL) sequences were expressed as recombinant proteins; the human and, to a low level, the African green monkey sequences bound soluble HCV E2 (sE2) and inhibited infection by retrovirus pseudotype particles bearing HCV glycoproteins (HCVpp). In contrast, mouse or rat CD81 proteins failed to bind sE2 or to inhibit HCVpp infection. However, CD81 proteins from all species, when expressed in HepG2 cells, conferred susceptibility to infection by HCVpp and cell culture-grown HCV to various levels, with the rat sequence being the least efficient. Recombinant human CD81 LEL inhibited HCVpp infectivity only if present during the virus-cell incubation, consistent with a role for CD81 after virus attachment. Amino acid changes that abrogate sE2 binding (I182F, N184Y, and F186S, alone or in combination) were introduced into human CD81. All three amino acid changes in human CD81 resulted in a molecule that still supported HCVpp infection, albeit with reduced efficiency. In summary, there is a remarkable plasticity in the range of CD81 sequences that can support HCV entry, suggesting that CD81 polymorphism may contribute to, but alone does not define, the HCV susceptibility of a species. In addition, the capacity to support viral entry is only partially reflected by assays measuring sE2 interaction with recombinant or full-length CD81 proteins

A two-way photonic interface for linking Sr+ transition at 422 nm to the telecommunications C-band

We report a single-stage bi-directional interface capable of linking Sr+ trapped ion qubits in a long-distance quantum network. Our interface converts photons between the Sr+ emission wavelength at 422 nm and the telecoms C-band to enable low-loss transmission over optical fiber. We have achieved both up- and down-conversion at the single photon level with efficiencies of 9.4% and 1.1% respectively. Furthermore we demonstrate noise levels that are low enough to allow for genuine quantum operation in the future.Comment: 5 pages, 4 figure

Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis.

Liver X receptors (LXRs) are transcriptional regulators of cellular and systemic cholesterol homeostasis. Under conditions of excess cholesterol, LXR activation induces the expression of several genes involved in cholesterol efflux, facilitates cholesterol esterification by promoting fatty acid synthesis, and inhibits cholesterol uptake by the low-density lipoprotein receptor. The fact that sterol content is maintained in a narrow range in most cell types and in the organism as a whole suggests that extensive crosstalk between regulatory pathways must exist. However, the molecular mechanisms that integrate LXRs with other lipid metabolic pathways are incompletely understood. Here we show that ligand activation of LXRs in mouse liver not only promotes cholesterol efflux, but also simultaneously inhibits cholesterol biosynthesis. We further identify the long non-coding RNA LeXis as a mediator of this effect. Hepatic LeXis expression is robustly induced in response to a Western diet (high in fat and cholesterol) or to pharmacological LXR activation. Raising or lowering LeXis levels in the liver affects the expression of genes involved in cholesterol biosynthesis and alters the cholesterol levels in the liver and plasma. LeXis interacts with and affects the DNA interactions of RALY, a heterogeneous ribonucleoprotein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the mouse liver. These findings outline a regulatory role for a non-coding RNA in lipid metabolism and advance our understanding of the mechanisms that coordinate sterol homeostasis