Ethical Problems in Evaluation Research

For some time, social scientists have been concerned with ethics in research. Much of what they have written has focused on research in general, but many of the points they raise are applicable to evaluation research in particular. Included among these concerns are informed consent, the right to treatment, the right to refuse treatment, implicit coercion, powerlessness of subjects, and, perhaps most important, external access to confidential data

Curriculum Alignment After Reforms: A Systematic Review with Considerations for Queensland Pre- and In-service Teachers

This systematic review synthesises research on curriculum alignment to suggest considerations for the implementation of the Senior secondary curriculum reform in Queensland, Australia. It focuses on the coherence of cognitive skills in the prescribed and enacted curriculum as these are typically the least aligned curriculum components. Search methods, which followed the PRISMA model, resulted in 108 relevant articles for qualitative synthesis. Results show that alignment after curriculum reforms is typically low. The use of educational taxonomies can support curriculum alignment. Marzano and Kendall’s (2007) New Taxonomy of Educational Objectives underpins the new Queensland Senior secondary syllabi which, in line with other Australian policy, encourage the explicit teaching of cognitive skills. Research is needed on the enacted cognitive skills curriculum in Queensland and its alignment with the reformed prescribed curriculum. To promote the successful implementation of the new Queensland Senior system, pre- and in-service teachers could engage with the New Taxonomy and best practice for teaching cognitive skills

Curriculum alignment after reforms: a systematic review with considerations for Queensland pre- and in-service teachers

This systematic review synthesises research on curriculum alignment to suggest considerations for the implementation of the Senior secondary curriculum reform in Queensland, Australia. It focuses on the coherence of cognitive skills in the prescribed and enacted curriculum as these are typically the least aligned curriculum components. Search methods, which followed the PRISMA model, resulted in 108 relevant articles for qualitative synthesis. Results show that alignment after curriculum reforms is typically low. The use of educational taxonomies can support curriculum alignment. Marzano and Kendall’s (2007) New Taxonomy of Educational Objectives underpins the new Queensland Senior secondary syllabi which, in line with other Australian policy, encourage the explicit teaching of cognitive skills. Research is needed on the enacted cognitive skills curriculum in Queensland and its alignment with the reformed prescribed curriculum. To promote the successful implementation of the new Queensland Senior system, pre- and in-service teachers could engage with the New Taxonomy and best practice for teaching cognitive skills

2016 Greenhouse Gas Inventory Report: Virginia Institute of Marine Science

During summer 2016 the VIMS Green Team completed an inventory of greenhouse gas (GHG) emissions from the Virginia Institute of Marine Science (VIMS) Gloucester Point campus during FY2015. GHG emissions were estimated using the Campus Carbon Calculator maintained by the Sustainability Institute at the University of New Hampshire, and compared to a previous GHG audit from FY2010

The Transit Ingress and the Tilted Orbit of the Extraordinarily Eccentric Exoplanet HD 80606b

We present the results of a transcontinental campaign to observe the 2009 June 5 transit of the exoplanet HD 80606b. We report the first detection of the transit ingress, revealing the transit duration to be 11.64 +/- 0.25 hr and allowing more robust determinations of the system parameters. Keck spectra obtained at midtransit exhibit an anomalous blueshift, giving definitive evidence that the stellar spin axis and planetary orbital axis are misaligned. The Keck data show that the projected spin-orbit angle is between 32-87 deg with 68.3% confidence and between 14-142 deg with 99.73% confidence. Thus the orbit of this planet is not only highly eccentric (e=0.93), but is also tilted away from the equatorial plane of its parent star. A large tilt had been predicted, based on the idea that the planet's eccentric orbit was caused by the Kozai mechanism. Independently of the theory, it is noteworthy that all 3 exoplanetary systems with known spin-orbit misalignments have massive planets on eccentric orbits, suggesting that those systems migrate differently than lower-mass planets on circular orbits.Comment: ApJ, in press [13 pg

Partial Purification of Peroxiredoxin-2 From Porcine Skeletal Muscle

Fresh meat quality is adversely affected by protein oxidation. However, a fundamental understanding of the diverse factors that influence protein oxidation in postmortem muscle remains elusive. Peroxiredoxin-2 (Prdx2), an antioxidant protein, is more abundant in tough meat based on instrumental tenderness; however, the role of Prdx2 in postmortem skeletal muscle is unknown. Therefore, the objective was to develop a method to purify Prdx2 from the diaphragm, psoas major, and longissimus lumborum. Proteins soluble at low ionic strength were extracted, dialyzed, clarified, and loaded onto a Q-Sepharose anion exchange column equilibrated with TEM (pH 7.4). In all preparations, Prdx2 eluted between about 75 and 115 mM NaCl. Immunoreactive fractions were dialyzed against TEM (pH 8.0), clarified, and loaded onto a DEAE-650S anion exchange column. In all preparations, Prdx2 eluted between approximately 55 and 75 mM NaCl. Immunoreactive fractions were concentrated and loaded onto a Superose-12 size exclusion column. Prdx2 was detected between 14 and 16 mL, and these fractions were concentrated and reduced with 0.5% 2-mercaptoethanol. A final pass over the Superose-12 column was conducted, and Prdx2 was detected in 2 peaks from 11–12 mL and 15–16 mL. Fractions 15–16 were pooled and retained for further experiments. The elution profile of Prdx2 in all 3 muscles was similar. The iden- tification of the primary protein was confirmed with liquid chromatography with tandem mass spectrometry. The purity of Prdx2 off the final Superose-12 column was approximately 33%, 52%, and 47% pure in the diaphragm, psoas major, and longissimus lumborum, respectively. This is the first report of a method to partially purify Prdx2 from skeletal muscle

Hierarchical Growth and Cosmic Star Formation: Enrichment, Outflows and Supernova Rates

The cosmic star formation histories are evaluated for different minimum masses of the initial halo structures, with allowance for realistic gas outflows. With a minimum halo mass of 10^{7} - 10^{8} M_odot and a moderate outflow efficiency, we reproduce both the current baryon fraction and the early chemical enrichment of the IGM. The intensity of the formation rate of ``normal'' stars is also well constrained by the observations: it has to be dominated by star formation in elliptical galaxies, except perhaps at very low redshift. The fraction of baryons in stars is predicted as are also the type Ia and II supernova event rates. Comparison with SN observations in the redshift range z=0-2 allows us to set strong constraints on the time delay of type Ia supernovae (a total delay of \sim 4 Gyr is required to fit the data), the lower end of the mass range of the progenitors (2 - 8 M_odot) and the fraction of white dwarfs that reproduce the type Ia supernova (about 1 per cent). The intensity in the initial starburst of zero metallicity stars below 270 M_\odot must be limited in order to avoid premature overenrichment of the IGM. Only about 10 - 20 % of the metals present in the IGM at z = 0 have been produced by population III stars at very high z. The remaining 80 - 90 % are ejected later by galaxies forming normal stars, with a maximum outflow efficiency occurring at a redshift of about 5. We conclude that 10^{-3} of the mass in baryons must lie in first massive stars in order to produce enough ionizing photons to allow early reionization of the IGM by z \sim 15.Comment: 51 pages, 23 eps figure

Review of Postmortem Protein Oxidation in Skeletal Muscle and the Role of the Peroxiredoxin Family of Endogenous Antioxidants

The development of fresh meat quality is dictated by biochemical changes during the perimortem and postmortem period. Lipid and protein oxidation in postmortem skeletal muscle and meat products is detrimental to product quality. The mechanisms that influence lipid and protein oxidation in fresh meat remain unelucidated. Peroxiredoxins are thiol-specific antioxidant proteins that are highly reactive and abundant and may be involved in limiting oxidation early postmortem. This review aims to provide a background on oxidation in skeletal muscle, peroxiredoxins, a summary of proteomic experiments associating peroxiredoxins and meat quality, and the importance of context from proteomic methods and results. Additional controlled experiments considering the cellular conditions of postmortem skeletal muscle are necessary to further understand the contribution of peroxiredoxins to fresh meat quality development