Novel insulation techniques for high voltage pulse transformers

This thesis describes a research investigation into novel designs of high voltage pulse transformers using magnetic insulation, which is the only practicable form of insulation for much of the equipment presently used in ultrahigh voltage pulsed-power work, including transmission lines and plasma opening switches. Although its use in transformers would bring important advantages in both size and weight reductions, a number of seemingly insurmountable problems have however so far prevented this. Two novel arrangements are presented in this thesis: one of these is a 500 kV transformer with self-magnetic insulation, and the other one is a 1 MV 'Tesla' transformer with external magnetic insulation. It is shown that both of these overcome the problems inherent in earlier designs and also offer considerable scope for further development in a number of important areas. It is believed that they represent the first working examples of magnetically-insulated transformers anywhere in the world. Modelling considerations of the transformers developed include both theoretical models and predicted characteristics. The filamentary technique used to describe mathematically the arrangements being investigated involves decomposition of the main conducting components into filamentary elements. The resulting equivalent electrical network includes all the mutual interactions that exist between the different filamentary elements, takes magnetic diffusion fully into account and enables the resistances and self and mutual inductances that are effective under fast transient conditions to be calculated. Theoretical results provided by the resulting mathematical models have been successfully validated by comparison with reliable experimental data. Much of the work detailed in the thesis has already been presented in high quality academic journals and at prestigious international conferences, and a solid theoretical and experimental basis has been laid down for future development and new progress into pulsed power system research

Image_1_Design for Pandemic Information: Examining the Effect of Graphs on Anxiety and Social Distancing Intentions in the COVID-19.TIF

To increase public awareness and disseminate health information, the WHO and health departments worldwide have been visualizing the latest statistics on the spread of COVID-19 to increase awareness and thus reduce its spread. Within various sources, graphs are frequently used to illustrate COVID-19 datasets. Limited research has provided insights into the effect of different graphs on emotional stress and ineffective behavioral strategies from a cross-cultural perspective. The result of current research suggests a graph with a high proportion size of the colored area (e.g., stacked area graph) might increase people's anxiety and social distancing intentions; people in collectivist culture might have a high level of anxiety and social distancing intentions; the effect of different graphs on social distancing intentions is mediated by anxiety experienced. Theoretical contribution and practical implications on health communication were also discussed in this study.</p

DataSheet_1_SAPHO Syndrome Complicated by Ankylosing Spondylitis Successfully Treated With Tofacitinib: A Case Report.docx

Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome, a type of chronic inflammatory disease, is rare and difficult to treat. Osteoarthropathy with skin involvement is the primary clinical manifestation of SAPHO syndrome. The unknown pathogenesis of SAPHO syndrome is speculated to be related to individual genetic differences, immune levels, microorganisms, and environmental factors. Tofacitinib, a novel small-molecule Janus kinase (JAK) inhibitor, has been used to treat rheumatoid arthritis. However, it also has great potential for the treatment of other immune diseases, including SAPHO syndrome. A 36-year-old man with chest and back pain for more than two months was admitted to our hospital. After admission, the patient developed a pustular rash and enteritis. SAPHO syndrome was diagnosed based on the above clinical manifestations, computed tomography (CT), and bone scintigraphy findings. Notably, the patient also had ankylosing spondylitis. Tofacitinib significantly improved the patient’s skin symptoms while preventing worsening of chest and back pain when adalimumab was discontinued. We report the first case of ankylosing spondylitis with SAPHO syndrome. In addition, it is also the first successful treatment thereof with tofacitinib. We hope to provide valuable information regarding the pathogenesis and treatment of SAPHO syndrome in this case.</p

Efficient One-Pot Synthesis of Mussel-Inspired Molecularly Imprinted Polymer Coated Graphene for Protein-Specific Recognition and Fast Separation

Molecular imprinting at nanomaterial surfaces has shown good prospects to extract templates easily and to achieve excellent performances such as large binding capacity and fast adsorption. In this work, we describe a one-step approach to synthesize a novel surface protein-imprinted nanomaterial employing graphene as the supporting substrate and dopamine as the polymerizing monomer. By simply immersing graphene oxide (GO) in a weak alkaline solution of dopamine (DA) containing bovine hemoglobin (BHb), GO nanosheet was readily converted to reduced GO (RGO) by dopamine with simultaneous capping by a thin polydopamine film imprinted with BHb leading to the BHb imprinted PDA@RGO nanomaterials. Fourier transform infrared (FT-IR), ultraviolet–visible (UV–vis), Raman spectra, X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and nitrogen adsorption experiments have been used to characterize the resulting imprinted PDA@RGO. The whole reaction process was conducted in aqueous solution at ambient temperature, which is easy to scale up at a low cost without pollution. In addition, because of the unique properties of graphene (large surface area, high surface-to-volume ratio) and polydopamine (high biocompatibility and controllable thickness), the prepared imprinted PDA@RGO not only possessed high binding capacity (198 mg/g) but also exhibited a fast adsorption kinetics (adsorb 89% of the maximum amount within 5 min) and good selectivity toward template protein (the imprinting factor α is 4.95). The outstanding recognizing behavior coupled to the low production cost and facile, quick, green preparation procedure makes the imprinted PDA@RGO attractive in specific protein recognition and separation, biosensors, and biochips

Image_2_Design for Pandemic Information: Examining the Effect of Graphs on Anxiety and Social Distancing Intentions in the COVID-19.TIF

To increase public awareness and disseminate health information, the WHO and health departments worldwide have been visualizing the latest statistics on the spread of COVID-19 to increase awareness and thus reduce its spread. Within various sources, graphs are frequently used to illustrate COVID-19 datasets. Limited research has provided insights into the effect of different graphs on emotional stress and ineffective behavioral strategies from a cross-cultural perspective. The result of current research suggests a graph with a high proportion size of the colored area (e.g., stacked area graph) might increase people's anxiety and social distancing intentions; people in collectivist culture might have a high level of anxiety and social distancing intentions; the effect of different graphs on social distancing intentions is mediated by anxiety experienced. Theoretical contribution and practical implications on health communication were also discussed in this study.</p

Data_Sheet_1_Design for Pandemic Information: Examining the Effect of Graphs on Anxiety and Social Distancing Intentions in the COVID-19.CSV

To increase public awareness and disseminate health information, the WHO and health departments worldwide have been visualizing the latest statistics on the spread of COVID-19 to increase awareness and thus reduce its spread. Within various sources, graphs are frequently used to illustrate COVID-19 datasets. Limited research has provided insights into the effect of different graphs on emotional stress and ineffective behavioral strategies from a cross-cultural perspective. The result of current research suggests a graph with a high proportion size of the colored area (e.g., stacked area graph) might increase people's anxiety and social distancing intentions; people in collectivist culture might have a high level of anxiety and social distancing intentions; the effect of different graphs on social distancing intentions is mediated by anxiety experienced. Theoretical contribution and practical implications on health communication were also discussed in this study.</p

Additional file 1 of Postoperative complications analysis of circular stapled versus linear stapled anastomosis for patients undergoing esophagectomy: a systematic review and meta-analysis

Additional File Fig. S1. The publishing bias in meta-analysis of the risk of anastomotic leakage between CS and L

Moving beyond Likert and Traditional Forced-Choice Scales: A Comprehensive Investigation of the Graded Forced-Choice Format

The graded forced-choice (FC) format has recently emerged as an alternative that may preserve the advantages and overcome the issues of the dichotomous FC measures. The current study presented the first large-scale evaluation of the performance of three types of FC measures (FC2, FC4 and FC5 with 2, 4 and 5 response options, respectively) and compared their performance to their Likert (LK) counterparts (LK2, LK4, and LK5) on (1) psychometric properties, (2) respondent reactions, and (3) susceptibility to response styles. Results showed that, compared to LK measures with the same number of response options, the three FC scales provided better support for the hypothesized factor structure, were perceived as more faking-resistant and cognitive demanding, and were less susceptible to response styles. FC4/5 and LK4/5 demonstrated similarly good reliability, while LK2 provided more reliable scores than FC2. When compared across the three FC measures, FC4 and FC5 displayed comparable psychometric performance and respondent reactions. FC4 exhibited a moderate presence of extreme response style, while FC5 had a weak presence of both extreme and middle response styles. Based on these findings, the study recommends the use of graded FC over dichotomous FC and LK, particularly FC5 when extreme response style is a concern.</p

sj-docx-1-mde-10.1177_23821205241252277 - Supplemental material for The Application of Problem-Based Learning Combined With Case-Based Learning in EEG Teaching

Supplemental material, sj-docx-1-mde-10.1177_23821205241252277 for The Application of Problem-Based Learning Combined With Case-Based Learning in EEG Teaching by Feng Li, Jing Luo and Hua Zhang in Journal of Medical Education and Curricular Development</p

Additional file 2 of Postoperative complications analysis of circular stapled versus linear stapled anastomosis for patients undergoing esophagectomy: a systematic review and meta-analysis

Additional File Fig. S2. The publishing bias in meta-analysis of the incidence of anastomotic stricture between CS and L