DataSheet_1_Recurrent retroperitoneal liposarcoma with multiple surgeries: a case report.zip

Retroperitoneal liposarcoma (RPLPS) is a rare malignant tumor that is typically treated with surgical resection. However, RPLPS often has a high rate of local recurrence, making it crucial to explore new treatment options. In this report, we present the case of a middle-aged woman who experienced seven recurrences and underwent seven surgeries following the initial resection. Currently, the patient’s condition remains stable after the eighth surgery. Although there have been numerous reports of RPLPS cases both domestically and internationally, instances of repeated recurrence like this are exceptionally rare. Therefore, we have gathered the patient’s case data and conducted a retrospective analysis, incorporating relevant literature, to enhance the understanding of this disease among clinical practitioners.</p

Regions of decreased grey matter volume at baseline in antipsychotic-naïve patients with schizophrenia compared to healthy controls. <i>P</i><0.001, uncorrected, threshold = 50.

<p>Regions of decreased grey matter volume at baseline in antipsychotic-naïve patients with schizophrenia compared to healthy controls. <i>P</i><0.001, uncorrected, threshold = 50.</p

Regions of increased grey matter volume from baseline to follow-up in patients with schizophrenia.

<p>Regions of increased grey matter volume from baseline to follow-up in patients with schizophrenia.</p

Comparisons of attention preference between healthy controls and MDD patients.

<p>In the invisible condition, the healthy controls showed significantly negative attention preference, but the MDD patients did not. The difference between the two groups was significant. In the visible condition, the two groups behaved similarly.</p

Comparison on attention preference in different sessions for healthy controls.

<p>The attention preference was indexed by difference in performance accuracy of the Gabor patch orientation judgment task. A positive value indicates attention preference to happy faces, and a negative value indicates attention preference to sad faces. In the 800-ms session, the invisible condition revealed significantly negative attention preference while the visible condition did not show significant valence preference. In the 200-ms session, no significant valence preference was observed in the invisible condition; the visible condition showed a positive trend though.</p

Individual attention preference of healthy controls and MDD patients.

<p>(A) Scatter plot of attention preference of MDD patients (blue points) and healthy controls (red points) across the visible (horizontal axis) and the invisible (vertical axis) conditions. The horizontal and vertical dash lines represent the no-preference level for the visible and invisible conditions respectively. Most healthy controls showed negative attention preference in the invisible condition (most red points are below horizontal dash line), but there was no such trend in MDD patients (the blue points show no obvious trend relative to the horizontal dash line). (B) Scatter plot of bootstrapped sample means of the two groups. For each participant group, 1000 datasets (with the same number of participants of the original group) are resampled from the original participants, and the mean attention preference metrics for both invisible and visible conditions for each dataset are represented by locations of the points on the scatter plot. The locations are projected to horizontal and vertical axes, based on which the distributions of attention preference metrics for the visible and invisible conditions are generated. The distribution for the MDD patients (blue histograms) and the healthy controls (red histograms) are clearly separated in the invisible condition but mixed together in the visible condition, showing a good separation between the two participant groups in the invisible paradigm.</p

Conceptual schema combining the implications of the current findings into a general framework.

<p>As proposed by numerical studies, the emotional stimuli are processed through three general phases, including analysis of stimulus features, recognition and response to emotion, and emotion regulation. The processing can be separated into conscious and unconscious parts. (A) Framework for healthy participants. Studies on conscious emotion processing have suggested a positive preference in healthy subjects <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0021881#pone.0021881-Yoon1" target="_blank">[39]</a>, we therefore mark the positive processing in conscious processing using a bold arrow and the negative processing using a narrow arrow. Our findings indicate that in the unconscious processing stage, the negative emotions may be processed through a stronger and faster pathway, as indicated by the bold arrow. (B) Framework for MDD patients. Our findings also suggest that MDD patients may have a deficit in unconscious negative emotion processing (see the thinner arrow for negative emotion in the unconscious part). This, in turn, may affect the conscious processing which then becomes shifted from positive to negative emotion preference (see the bolder arrow for negative emotion in the conscious part) in order to compensate the hitherto incomplete processing of negative emotions in the deficient unconscious mode.</p

Individual attention preference of healthy participants in the invisible and visible conditions.

<p>(A) Scatter plot of individual attention preference across the invisible and the visible conditions. Each dot represents the attention preference for a participant. The locations of the dots are determined by the visible (horizontal axis) and the invisible (vertical axis) conditions. The zero levels that indicate no attention preference are illustrated using dotted-lines. Except two participants, all others show a negative attention preference in the invisible condition, but no such trend appears in the visible conditions. (B) Scatter plot of bootstrapped sample means of the attention preference. 1000 datasets are resampled from the original participants, each containing 20 participants, and the mean attention preference metrics for both invisible (horizontal axis) and visible conditions (vertical axis) for each resampled dataset are represented by a point on the scatter plot. The locations of the points are separately projected to the horizontal and the vertical axes, and the histograms are used to represent the distribution of the projected locations for the visible and the invisible conditions respectively. In the invisible condition, the distribution is below the zero level and has a relatively small deviation, indicating a robust negative bias in population level, while the distribution for the visible condition is centered at the zero.</p

Clinical information summary of the participants.

<p>*Antidepressants (mg/d): Escitalopram(10); Sertraline(50); Paroxetine(20); Fluvoxamine(50); Fluoxetine(20); Venlafaxine(75); Citalopram(20); Mirtazapine(15); Doxepin (25); Trazodone (50); John's Wort Extracts (300).</p

Schematic representation of the experimental paradigm for the invisible and visible conditions.

<p>In the invisible condition, dynamic noise patches were presented to the dominant eye and faces with happy and sad emotional expressions were presented to the other eye. The duration of the face presentation was 800 ms for Experiments 1 and 3, and 200 ms for Experiment 2. After a 100-ms interval, participants were instructed to press one of two buttons as soon and accurate as possible to indicate the perceived orientation (clockwise or counter-clockwise) of a Gabor patch presented for 100 ms. In the visible condition, the dynamic noise patches were replaced by the same pair of faces presented to the other eye.</p