Vapor-Solid Growth of Molybdenum Disulfide Nanosheets

The goal of this thesis is to growth a high-quality molybdenum disulfide (MoS2) nanosheets composed of a couple of monolayers. These materials are promising for nanoelectronic, optoelectronic, valleytronic, and energy harvesting devices. Its sizable bandgap (in visible region) and many other extraordinary electronic and optoelectronic properties make it a promising potential substitute of Si in conventional electronic application. An important next step is the fabrication of monolayer or bilayer MoS2 nanosheets. Various methods have been reported in recent years to prepare high-quality material. Among them, chemical vapor deposition has been considered the most frequently-used method which was previously widely used for the growth of thin films and nanomaterials such as nanowires, nanotubes, and graphene. The first part of this thesis gives a background introduction to MoS2 materials especially the growth of MoS2 nanosheet. In the second part of the thesis the CVD growth of MoS2 growth is presented and the characterization of as-grown MoS2 nanosheets is discussed. Finally a summary chapter is presente

Table_1_Case Report: Identification of the First Synonymous Variant of Myosin Binding Protein C3 (c.24A>C, p.P8P) Altering RNA Splicing in a Cardiomyopathy and Sudden Cardiac Death Case.docx

BackgroundSudden cardiac death (SCD), based on sudden cardiac ejection cessation, is an unexpected death. Primary cardiomyopathies, including dilated cardiomyopathy (DCM), are one of main causes of SCD. The DCM is characterized by a cardiac dilatation and a reduced systolic function with a prevalence of 1/250 in adults. The DCM has been reported with more than 60 disease-causing genes, and MYBPC3 variants are one of the most common and well-known causes of DCM.MethodsWe identified a 29-year-old female who died of SCD. We performed a whole-exome sequencing (WES) to detect her genetic etiology and used minigene modeling and immunohistochemistry staining to verify the pathogenicity.ResultsWe determined that the woman died of SCD caused by DCM due to an identified novel synonymous variant of MYBPC3 (NM_000256.3: c.24A>C, p.P8P) in the deceased. The variant can result in abnormal splicing, which was confirmed by minigene models and immunohistochemistry staining.ConclusionWe may have identified the first deleterious synonymous variant of MYBPC3 in an SCD case and verified its significant impact on RNA splicing. Our description enriched the spectrum of MYBPC3 variants and emphasized the significance of synonymous variants that are always disregarded in genetic screening.</p

Sulfur deposition suppressed nitrogen-induced soil N2O emission from a subtropical forestland in southeastern China

Subtropical forestland soils are important sources of nitrous oxide (N2O); however few studies haveevaluated the effects of sulfate (S) deposition and its interaction with nitrogen (N) on soil N2O emis-sions from subtropical forestland. A field experiment was conducted in subtropical forestland in Yingtan,Jiangxi Province, China, between June 2011 and May 2013, to measure soil N2O fluxes under three N(NO3−) application levels (0, 40, and 80 kg N ha−1yr−1), two S (SO42−) levels (0 and 45 kg S ha−1yr−1), andtheir combinations. The soil N2O flux was significantly (P < 0.05) correlated with only soil temperaturein all treatments over the study period; however, soil moisture, and NH4+and NO3−contents were alsoincluded in the stepwise multiple linear regression equations during the N and/or S application period(March to September). N2O emissions under natural conditions in the subtropical forestland were esti-mated at 0.42 kg N2O-N ha−1yr−1, and were significantly (P < 0.05) increased by 97–330% under the Napplication. In contrast, soil N2O emissions decreased to 0.36 kg N2O-N ha−1yr−1in the S-applied soil andwere significantly (P < 0.05) reduced by 27–36% in the S plus N-amended soils. Our results indicated thatatmospheric N deposition potentially increases soil N2O emissions in subtropical forestland, whereas Saddition has the potential to mitigate N2O emissions. Given that increased N deposition is expected inthe future, S deposition in subtropical forestland soils could suppress N2O emissions to some extent

Effect of application of dairy manure, effluent and inorganic fertilizer on nitrogen leaching in clayey fluvo-aquic soil: a lysimeter study

Dairy farm manure and effluent are applied to cropland in China to provide a source of plant nutrients, but there are concerns over its effect on nitrogen (N) leaching loss and groundwater quality. To investigate the effects of land application of dairy manure and effluent on potential N leaching loss, two lysimeter trials were set up in clayey fluvo-aquic soil in a winter wheat-summer maize rotation cropping system on the North China Plain. The solid dairy manure trial included control without N fertilization (CK), inorganic N fertilizer (SNPK), and fresh (RAW) and composted (COM) dairy manure. The liquid dairy effluent trial consisted of control without N fertilization (CF), inorganic N fertilizer (ENPK), and fresh (FDE) and stored (SDE) dairy effluent. The N application rate was 225 kg N ha− 1 for inorganic N fertilizer, dairy manure, and effluent treatments in both seasons. Annual N leaching loss (ANLL) was highest in SNPK (53.02 and 16.21 kg N ha− 1 in 2013/2014 and 2014/2015, respectively), which were 1.65- and 2.04-fold that of COM, and 1.59- and 1.26-fold that of RAW. In the effluent trial (2014/2015), ANLL for ENPK and SDE (16.22 and 16.86 kg N ha− 1, respectively) were significantly higher than CF and FDE (6.3 and 13.21 kg N ha− 1, respectively). NO3− contributed the most (34–92%) to total N leaching loss among all treatments, followed by dissolved organic N (14–57%). COM showed the lowest N leaching loss due to a reduction in NO3− loss. Yield-scaled N leaching in COM (0.35 kg N Mg− 1 silage) was significantly (P < 0.05) lower than that in the other fertilization treatments. Therefore, the use of composted dairy manure should be increased and that of inorganic fertilizer decreased to reduce N leaching loss while ensuring high crop yield in the North China Plain

Additional file 1 of Identification of key genes associated with polycystic ovary syndrome (PCOS) and ovarian cancer using an integrated bioinformatics analysis

Additional file 1