Additional file 1 of The sweet spot: fasting glucose, cardiovascular disease, and mortality in older adults with diabetes: a nationwide population-based study

Additional file 1. Study population

Additional file 3 of The sweet spot: fasting glucose, cardiovascular disease, and mortality in older adults with diabetes: a nationwide population-based study

Additional file 3. Hazard ratios and 95% confidence intervals of cardiovascular event according to the 10 categories of fasting glucose level at baseline, estimated by Fine-Gray regression

Additional file 5 of The sweet spot: fasting glucose, cardiovascular disease, and mortality in older adults with diabetes: a nationwide population-based study

Additional file 5. Hazard ratios and 95% confidence intervals of all-cause mortality, and CVD by 10 categories of fasting glucose level at baseline

Additional file 4 of The sweet spot: fasting glucose, cardiovascular disease, and mortality in older adults with diabetes: a nationwide population-based study

Additional file 4. Hazard ratios and 95% confidence intervals of all-cause mortality (A), cardiovascular events (myocardial infarction or stroke) (B) by 10 categories of fasting glucose level stratified by sex

Additional file 2 of The sweet spot: fasting glucose, cardiovascular disease, and mortality in older adults with diabetes: a nationwide population-based study

Additional file 2. Characteristics of participants

Technoeconomic and Environmental Evaluation of Sodium Bicarbonate Production Using CO₂ from Flue Gas of a Coal-Fired Power Plant

This study analyzes the technical, economic, and environmental feasibility of a CO2 mineralization process, which has great potential in terms of CO2 utilization capacity. The chosen process is the sodium bicarbonate manufacturing process that uses sodium carbonate solution with CO2 that is obtained from the flue gas produced from a coal-fired power plant. The technical feasibility analysis involves performance evaluation, which is conducted using a bench-scale apparatus capable of producing sodium bicarbonate with a purity of 99% and greater. According to the analysis, the CO2 reduction potential of the proposed CO2 utilization process is approximately 0.33 ton of CO2 per ton of sodium bicarbonate produced. When comparing CO2 emissions for the production of 1 ton of sodium bicarbonate, the CO2 utilization process of this study produces approximately 0.10 ton of CO2 emissions excluding the CO2 footprint of sodium carbonate, which is the key raw material. If the footprint of sodium carbonate from the Solvay process is used to account for it, this number goes up to 1.96 tons compared to the 1.69 tons produced by the conventional process. In addition, this study evaluates the economic feasibility of a commercial-scale plant based on the proposed technology with the capacity of 30 000 tons of sodium bicarbonate by utilizing approximately 10 000 tons of CO2 per year. Most of the analyzed cases indicate strong economic potential with a benefit-cost ratio and internal rate of return value of 1.45 and 80.5%, respectively

Longitudinal association between hypertension and psoriasis incidence according to age and sex.

Longitudinal association between hypertension and psoriasis incidence according to age and sex.</p

Characteristics of the study population.

Characteristics of the study population.</p

Kaplan–Meier survival curve.

The overall psoriasis-free survival analyses for the hypertension and comparison groups are shown. The log-rank P value is significant, indicating a significant difference in psoriasis incidence between the hypertension and comparison groups.</p

Tuning the Permeability of Polymer Hydrogel Capsules: An Investigation of Cross-Linking Density, Membrane Thickness, and Cross-Linkers

Nanoengineered poly(methacrylic acid) hydrogel capsules (PMA HCs) are promising candidate carriers for biomedical applications, especially in the areas of drug delivery, encapsulated catalysis, and cell mimicry. The assembly, stability, and degradation of these carriers, as well as their use for the encapsulation of therapeutics, have received considerable attention. However, tailoring the permeability properties of PMA HCs to various types of cargo remains largely unexplored. Herein, we investigate fundamental parameters that govern the structural integrity and the capability of PMA HCs to encapsulate macromolecular cargo. The thiol content of the constituent polymers and the number of deposited polymer layers are shown to be key factors in controlling cargo retention within the PMA HCs. We further introduce a new strategy to achieve disulfide cross-linking for PMA HCs via a thiol−disulfide exchange in order to obtain capsules with superior cargo retention characteristics. Finally, we provide evidence for the semipermeable nature of PMA HCs based on the charge of the solutes and demonstrate that rational design of these systems can yield capsules with specific cargo retention properties. This work contributes toward the development of multilayered polymer capsules and PMA HCs and associated applications in biomedicine