An effective algorithm for simulating acoustical wave propagation

Abstract In this paper, the acoustical wave propagator scheme is implemented in Fortran for predicting sound propagation in a one-dimensional duct. Example calculations are performed for a semi-infinite duct and a duct with a solid blockage. Numerical accuracy of our results is examined and compared with the finite-difference time-domain method. This scheme is found to be highly accurate and computationally effective for describing the time-domain evolution of acoustic waves. Multiple reflections with... Title of program: AWP.f90, v 1.0 Catalogue Id: ADRE_v1_0 Nature of problem In this paper, the acoustical wave propagator scheme is implemented in Fortran for predicting sound propagation in a one-dimensional duct. Example calculations are performed for a semi-infinite duct and a duct with a solid blockage. Numerical accuracy of our results is examined and compared with the finite-difference time-domain method. This scheme is found to be highly accurate and computationally effective for describing the time-domain evolution of acoustic waves. Multiple reflections within ... Versions of this program held in the CPC repository in Mendeley Data ADRE_v1_0; AWP.f90, v 1.0; 10.1016/S0010-4655(02)00700-2 This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2019

Influences of melatonin and endotoxin lipopolysaccharide on goose productive performance and gut microbiota

1. This study investigated the impact of melatonin and LPS on goose growth and the intestinal microbiome. 2. Geese were injected with a control solution (C), LPS solution (L), melatonin solution (M), and both LPS and melatonin solution (LM), respectively. Faecal samples from each group were used to analyse microbial diversity and function for geese with different treatments. 3. The results showed that the M group had a little improvement in growth compared with the C group, but were much higher than the L and LM groups. A clear distinction between M and other groups was seen with regard to alpha and beta diversity in the biome. The dominant bacteria phyla were Firmicutes, Proteobacteria, and Actinobacteria spp. in all groups. Unclassified bacteria were dominant in all groups at the genus level. Significant KEGG enrichment pathways in the M group were involved in processing metabolism and genetic information, while the L group was related to processing metabolism and environmental information. 4. This study provided a foundation for future studies targeting the specific effect of important bacterial populations on goose growth performance.</p

Regulation of semaphorin 4D expression and cell proliferation of ovarian cancer by ERalpha and ERbeta

Ovarian cancer is one of the most common malignancies in women. Semaphorin 4D (sema 4D) is involved in the progress of multiple cancers. In the presence of estrogen-like ligands, estrogen receptors (ERα and ERβ) participate in the progress of breast and ovarian cancers by transcriptional regulation. The aim of the study was to investigate the role of sema 4D and elucidate the regulatory pattern of ERα and ERβ on sema 4D expression in ovarian cancers. Sema 4D levels were up-regulated in ovarian cancer SKOV-3 cells. Patients with malignant ovarian cancers had significantly higher sema 4D levels than controls, suggesting an oncogene role of sema 4D in ovarian cancer. ERα expressions were up-regulated in SKOV-3 cells compared with normal ovarian IOSE80 epithelial cells. Conversely, down-regulation of ERβ was observed in SKOV-3 cells. Forced over-expression of ERα and ERβ in SKOV-3 cells was manipulated to establish ERα+ and ERβ+ SKOV-3 cell lines. Incubation of ERα+ SKOV-3 cells with ERs agonist 17β-estradiol (E2) significantly enhanced sema 4D expression and rate of cell proliferation. Incubated with E2, ERβ+ SKOV-3 cells showed lower sema 4D expression and cell proliferation. Blocking ERα and ERβ activities with ICI182-780 inhibitor, sema 4D expressions and cell proliferation of ERα+ and ERβ+ SKOV-3 cells were recovered to control levels. Taken together, the data showed that sema 4D expression was positively correlated with the progress of ovarian cancer. ERα positively regulated sema 4D expression and accelerated cell proliferation. ERβ negatively regulated sema 4D expression and inhibited cell multiplication.</div

Integrated photonics enables continuous-beam electron phase modulation

The ability to tailor laser light on a chip using integrated photonics has allowed for extensive control over fundamental light-matter interactions in manifold quantum systems including atoms, trapped ions, quantum dots, and defect centers. Free electrons, enabling high-resolution microscopy for decades, are increasingly becoming the subject of laser-based quantum manipulation. Using free-space optical excitation and intense laser pulses, this has led to the observation of free-electron quantum walks, attosecond electron pulses, and imaging of electromagnetic fields. Enhancing the interaction with electron beams through chip-based photonics promises unique applications in nanoscale quantum control and sensing, but has yet to enter electron microscopy. Here, we merge integrated photonics with electron microscopy, demonstrating coherent phase modulation of an electron beam using a silicon nitride microresonator driven by a continuous-wave laser. The high-Q factor (~$10^6$) cavity enhancement and a waveguide designed for phase matching lead to efficient electron-light scattering at unprecedentedly low, few-microwatt optical powers. Specifically, we fully deplete the initial electron state at a cavity-coupled power of 6 $\mu$W and create >500 photon sidebands for only 38 mW in the bus waveguide. Moreover, we demonstrate $\mu$eV electron energy gain spectroscopy (EEGS). Providing simultaneous optical and electronic spectroscopy of the resonant cavity, the fiber-coupled photonic structures feature single-mode electron-light interaction with full control over the input and output channels. This approach establishes a versatile framework for exploring free-electron quantum optics, with future developments in strong coupling, local quantum probing, and electron-photon entanglement. Our results highlight the potential of integrated photonics to efficiently interface free electrons and light