182 research outputs found

    Efficiency Measurement of General Activities of One Stop Crisis Centre: A Study on Khulna Medical College Hospital, Bangladesh

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    The present study was an attempt to find out the efficiency level of general activities of OCC in KMCH. This study based on the primary and the secondary data concludes that the efficient organizational practices can remove the inefficiency of the organization for a long time and vice versa. The author considered eight activities followed by OCC in KMCH. The hypotheses were developed in the light of objectives of this study, where, H0= there is no difference between observed mean and expected mean of each organizational activity as well as H1= there is difference between mean of each organizational activity. Moreover, z value has been calculated for testing hypothesis by using the formula: where three variables (Medical treatment, Social welfare service, Security by OCC police) were rejected and rests of five variables such as Legal examination, Psychological counseling, Legal counseling, Rehabilitation, and Temporary Shelter are accepted. So OCC should improve all of the accepted activities for ensuring the smooth service for the victim. Key Word: Khulna Medical College Hospital (KMCH), One Stop Crisis Centre (OCC), Violence against Women (VAW

    Should we have voluntary censorship code for Netflix?

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    NETFLIX allows customers to watch television shows, movies, documentaries on Internet-connected devices, such as tablets, computers, mobile phones and smart TVs. What is worrying is that Netflix is broadcasting original programmes without censorship. Malaysia has the Film Censorship Act 2002 to protect people from the negative influence that can result from watching uncensored films

    Measuring Customer Satisfaction of Mobile Phone Users: A Comparative Study between Grameen Phone and Teletalk Based on Khulna City, Bangladesh

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    The present study is basically an attempt to examine the customer satisfaction toward the existing attributes of Grameen phone and Teletalk based on Fishbein’s Multi-Atribute Attitude Model. Twenty factors have been considered for justifying the result of this study. The research is based on the primary data. 200 respondents have been selected randomly from different areas of Khulna City in Bangladesh. In this study, the hypotheses were developed in the light of objectives of this study, where, H0 = there is no difference between mean of each attribute of Grameen phone and Teletalk, and H1 = there is difference between mean of each attribute of Grameen phone and Teletalk,. It has found that overall customer attitude toward Grameen Phone is 166.1923, whereas Teletalk is 78.939. In most of the cases (17 out of 20), customers show positive attitude towards Grameen Phone than that of Teletalk. Key Words: Customer Satisfaction, Multi-Attribute Attitude Model

    Organ Donation and Transplantation Issues in Islam and Present Situation

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    All of the major faiths including Islam, Christianity, Hinduism, Judaism, and Sikhism support organ donation and transplantation. Recent advances in the field of organ donation and organ transplant have introduced new hope for the treatment of serious diseases. Most of the people of many religions still believe that organ donation is prohibited by religion but it not true.  This article has tried to focus that; organ donation is not prohibited by Islam. In addition, religions encourage people to help each other. This article has also tried to encourage people to donate organ. Basically, I discuss based on Quran and Hadith of Prophet Mohammad (SWA).  It is qualitative research.  Primary and secondary resources are used in this paper. The information has been taken from many readings, articles, books, and status. Many people are dying every day for lacking of organ. For example, in the year 2000, more than 5,500 Americans died awaiting transplants and there are currently over 80,000 people awaiting transplants. So that, most of the government and religious scholar are encouraging people to donate organ. Keywords: Organ donation, Transplantation, Islam, Human organ, Patient

    Regulation of angiogenic processes in omental endothelial cells during metastasis of epithelial ovarian cancer

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    Epithelial ovarian cancer frequently metastasizes to the omentum, a process that requires pro-angiogenic activation of local microvascular endothelial cells (ECs) by tumour-secreted factors. We have previously shown that ovarian cancer cells secrete factors, other than vascular endothelial growth factor (VEGF), with possible roles in metastatic angiogenesis including the lysosomal proteases cathepsin L (CathL) and cathepsin D (CathD), and insulin-like growth factor binding protein 7 (IGFBP7). However, the mechanisms by which these factors may contribute to omental endothelial angiogenic changes are unknown. Therefore the aims of this thesis were a) to examine disease relevant human omental microvascular endothelial cell (HOMEC) proliferation, migration and angiogenesis tube-formation induced by CathL, CathD and IGFBP7; b) to investigate whether CathL and CathD act via a proteolytic or non-proteolytic mechanism; c) to identify activated downstream intracellular signalling cascades in HOMECs and their activation in proliferation and migration; and finally d) to identify activated cell surface receptors by these factors. CathL, CathD and IGFBP7 significantly induced proliferation and migration in HOMECs, with CathL and CathD acting in a non-proteolytic manner. Proteome-profiler and ELISA data identified increased phosphorylation of the ERK1/2 and AKT (protein kinase B) pathways in HOMECs in response to these factors. CathL induced HOMEC proliferation and migration via the ERK1/2 pathway, whereas, although CathD-induced proliferation was mediated by activation of ERK1/2, its migratory effect was dependent on both ERK1/2 and AKT pathways. Interestingly, CathL induced secretion of galectin-1 (Gal1) from HOMECs which in turn significantly induced HOMEC proliferation via ERK1/2. However, none of the ERK1/2 or AKT pathways was observed to be active in Gal1-induced HOMEC migration. Interestingly, Gal1-induced proliferation and migration were significantly inhibited by L-glucose, suggesting a role for a receptor with extracellular sugar moieties. IGFBP7-induced migration was shown to be mediated via activation of the ERK1/2 pathway only. CathL, Gal1 and IGFBP7 significantly induced angiogenesis tube-formation in HOMECs which was not observed in CathD-treated cells. Receptor tyrosine kinase array revealed activation of Tie-1 and VEGF receptor type 2 (VEGFR2) in CathL and IGFBP7-treated HOMECs respectively. In conclusion, all CathL, CathD, Gal1 and IGFBP7 have the potential to act as proangiogenic factors in the metastasis of ovarian cancer to the omentum. These in vitro data suggest all four factors activate intracellular pathways which are involved in well-known angiogenesis models.FORCE Cancer Charit
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